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    Also known as: 50700-72-6, Norcuron, Org nc 45, Vecuronii bromidum, Bromuro de vecuronio, Vecuronium (bromide)
    Molecular Formula
    C34H57BrN2O4
    Molecular Weight
    637.7  g/mol
    InChI Key
    VEPSYABRBFXYIB-PWXDFCLTSA-M
    FDA UNII
    7E4PHP5N1D
    Vecuronium Bromide
    Monoquaternary homolog of PANCURONIUM. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other established neuromuscular blocking agents.
    1 2D Structure

    Vecuronium Bromide

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetyloxy-10,13-dimethyl-16-(1-methylpiperidin-1-ium-1-yl)-2-piperidin-1-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate;bromide
    2.1.2 InChI
    InChI=1S/C34H57N2O4.BrH/c1-23(37)39-31-20-25-12-13-26-27(34(25,4)22-29(31)35-16-8-6-9-17-35)14-15-33(3)28(26)21-30(32(33)40-24(2)38)36(5)18-10-7-11-19-36;/h25-32H,6-22H2,1-5H3;1H/q+1;/p-1/t25-,26+,27-,28-,29-,30-,31-,32-,33-,34-;/m0./s1
    2.1.3 InChI Key
    VEPSYABRBFXYIB-PWXDFCLTSA-M
    2.1.4 Canonical SMILES
    CC(=O)OC1CC2CCC3C(C2(CC1N4CCCCC4)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-]
    2.1.5 Isomeric SMILES
    CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@@H]([C@]2(C[C@@H]1N4CCCCC4)C)CC[C@]5([C@H]3C[C@@H]([C@@H]5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-]
    2.2 Other Identifiers
    2.2.1 UNII
    7E4PHP5N1D
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Bromide, Vecuronium

    2. Citrate, Vecuronium

    3. Hydrobromide, Vecuronium

    4. Hydrochloride, Vecuronium

    5. Maleate, Vecuronium

    6. Nc 45

    7. Nc-45

    8. Nc45

    9. Norcuron

    10. Org Nc 45

    11. Org Nc45

    12. Org-nc 45

    13. Org-nc-45

    14. Org-nc45

    15. Orgnc 45

    16. Orgnc45

    17. Phosphate, Vecuronium

    18. Vecuronium

    19. Vecuronium Bromide, Quaternary Ion

    20. Vecuronium Citrate

    21. Vecuronium Hydrobromide

    22. Vecuronium Hydrochloride

    23. Vecuronium Maleate

    24. Vecuronium Phosphate

    2.3.2 Depositor-Supplied Synonyms

    1. 50700-72-6

    2. Norcuron

    3. Org Nc 45

    4. Vecuronii Bromidum

    5. Bromuro De Vecuronio

    6. Vecuronium (bromide)

    7. Bromure De Vecuronium

    8. Org-nc 45

    9. 7e4php5n1d

    10. Acetate;bromide

    11. Chebi:9940

    12. Musculax

    13. Nsc-759184

    14. 1-(3alpha,17beta-dihydroxy-2beta-piperidino-5alpha-androstan-16beta,5alpha-yl)-1-methylpiperidinium Bromide, Diacetate

    15. Dsstox_cid_3736

    16. (+)-1-(3,17-diacetoxy-2-piperidino-5-androstan-16-yl)-1-methylpiperidinium Bromide

    17. Dsstox_rid_77174

    18. Dsstox_gsid_23736

    19. [(2s,3s,10s,13s,16s,17r)-17-acetyloxy-10,13-dimethyl-16-(1-methylpiperidin-1-ium-1-yl)-2-piperidin-1-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-3-yl] Acetate;bromide

    20. [(2s,3s,5s,8r,9s,10s,13s,14s,16s,17r)-17-acetyloxy-10,13-dimethyl-16-(1-methylpiperidin-1-ium-1-yl)-2-piperidin-1-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-3-yl] Acetate;bromide

    21. Nc-45

    22. 1-[(2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide Hydrate

    23. Cas-50700-72-6

    24. Vecuronii Bromidum [inn-latin]

    25. Ncgc00167467-01

    26. Bromure De Vecuronium [inn-french]

    27. Bromuro De Vecuronio [inn-spanish]

    28. Einecs 256-723-9

    29. Unii-7e4php5n1d

    30. Vecronium Bromide

    31. Norcuron (tn)

    32. [(2s,3s,5s,8r,9s,10s,13s,14s,16s,17r)-17-acetyloxy-10,13-dimethyl-16-(1-methylpiperidin-1-ium-1-yl)-2-piperidin-1-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-3-yl]

    33. Mfcd00867762

    34. Vecuronium Bromide [usan:usp:inn:ban:jan]

    35. 5alpha-androstan-3alpha,17beta-diol, 16beta-pipecolinio-2beta-piperidino-,bromide,diacetate

    36. Schembl22250

    37. Mls001424317

    38. Piperidinium, 1-((2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl)-1-methyl-, Bromide

    39. Vecuronium Bromide [mi]

    40. Chembl1200629

    41. Dtxsid1023736

    42. Vecuronium Bromide [inn]

    43. Vecuronium Bromide [jan]

    44. Hy-b0118a

    45. Vecuronium For System Suitability

    46. Vecuronium Bromide [usan]

    47. Hms2052i21

    48. Hms3715l15

    49. Hms3884c15

    50. Vecuronium Bromide [vandf]

    51. Vecuronium Bromide [mart.]

    52. 1-[(1s,2s,4s,5s,7s,10r,11s,13s,14r,15s)-5,14-bis(acetyloxy)-2,15-dimethyl-4-(piperidin-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-13-yl]-1-methylpiperidin-1-ium Bromide

    53. Bcp06528

    54. Vecuronium Bromide (jan/usp/inn)

    55. Vecuronium Bromide [usp-rs]

    56. Vecuronium Bromide [who-dd]

    57. Tox21_112471

    58. Akos005145904

    59. Akos007930694

    60. Tox21_112471_1

    61. Ac-2000

    62. Ccg-101147

    63. Cs-1881

    64. Nc00397

    65. Nsc 759184

    66. Vecuronium Bromide [ep Impurity]

    67. Vecuronium Bromide [orange Book]

    68. Ncgc00167467-03

    69. Vecuronium Bromide [ep Monograph]

    70. 1-((2s,3s,5s,8r,9s,10s,13s,14s,16s,17r)-3,17-diacetoxy-10,13-dimethyl-2-(piperidin-1-yl)hexadecahydro-1h-cyclopenta[a]phenanthren-16-yl)-1-methylpiperidin-1-ium Bromide

    71. Ds-12625

    72. Piperidinium, 1-(3-alpha,17-beta-diacetoxy-2-beta-piperidino-5-alpha-androstan-16-beta-yl)-1-methyl-, Bromide

    73. Smr000471625

    74. Vecuronium Bromide [usp Monograph]

    75. S1405

    76. V0120

    77. D00767

    78. Pancuronium Bromide Impurity, Vecuronium Bromide -

    79. Sr-01000763634

    80. Pancuronium Bromide Impurity D [ep Impurity]

    81. Q-101014

    82. Sr-01000763634-3

    83. Q27108523

    84. Z1551429734

    85. Vecuronium Bromide, European Pharmacopoeia (ep) Reference Standard

    86. Pancuronium Bromide Impurity, Vecuronium Bromide - [usp Impurity]

    87. Vecuronium Bromide, United States Pharmacopeia (usp) Reference Standard

    88. 1-(3,17-diacetoxy-2-piperidino-5-androstan-16-yl)-1-methylpiperidinium Bromide

    89. Vecuronium Bromide, Pharmaceutical Secondary Standard; Certified Reference Material

    90. Vecuronium For Peak Identification, European Pharmacopoeia (ep) Reference Standard

    91. Vecuronium For System Suitability, European Pharmacopoeia (ep) Reference Standard

    92. (2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-16-(1-methylpiperidinium-1-yl)-2-(piperidin-1-yl)androstane Bromide

    93. (2beta,3alpha,5alpha,16beta,17beta)-3,17-diacetoxy-16-(1-methylpiperidinium-1-yl)-2-(piperidin-1-yl)androstane Bromide

    94. 1-((2s,3s,5s,10s,13s,16s,17r)-3,17-diacetoxy-10,13-dimethyl-2-(piperidin-1-yl)hexadecahydro-1h-cyclopenta[a]phenanthren-16-yl)-1-methylpiperidin-1-ium Bromide

    95. 1-((2s,3s,5s,10s,13s,16s,17r)-3,17-diacetoxy-10,13-dimethyl-2-(piperidin-1-yl)hexadecahydro-1h-cyclopenta[a]phenanthren-16-yl)-1-methylpiperidin-1-iumbromide

    96. 1-(3.alpha.,17.beta.-dihydroxy-2.beta.-piperidino-5.alpha.-androstan-16.beta.,5.alpha.-yl)-1-methylpiperidinium Bromide, Diacetate

    97. 1-[(2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide

    98. 1-[3alpha,17beta-bis(acetoxy)-2beta-(1-piperidinyl)-5alpha-androstan-16beta-yl]-1-methylpiperidinium Bromide

    99. Piperidinium, 1-((2.beta.,3.alpha.,5.alpha.,16.beta.,17.beta.)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl)-1-methyl-, Bromide

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 637.7 g/mol
    Molecular Formula C34H57BrN2O4
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count6
    Exact Mass636.35017 g/mol
    Monoisotopic Mass636.35017 g/mol
    Topological Polar Surface Area55.8 Ų
    Heavy Atom Count41
    Formal Charge0
    Complexity958
    Isotope Atom Count0
    Defined Atom Stereocenter Count10
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameVecuronium bromide
    Drug LabelVecuronium Bromide for Injection is a nondepolarizing neuromuscular blocking agent of intermediate duration, chemically designated as 1-(3,17-Dihydroxy-2-piperidino-5- androstan-16,5-yl)-1-methylpiperidinium bromide, diacetate. The struct...
    Active IngredientVecuronium bromide
    Dosage FormInjectable
    RouteInjection
    Strength10mg/vial; 20mg/vial
    Market StatusPrescription
    CompanyBedford; Hospira; Teva Pharms Usa; Sun Pharma Global; Mustafa Nevzat; Agila Speclts

    2 of 2  
    Drug NameVecuronium bromide
    Drug LabelVecuronium Bromide for Injection is a nondepolarizing neuromuscular blocking agent of intermediate duration, chemically designated as 1-(3,17-Dihydroxy-2-piperidino-5- androstan-16,5-yl)-1-methylpiperidinium bromide, diacetate. The struct...
    Active IngredientVecuronium bromide
    Dosage FormInjectable
    RouteInjection
    Strength10mg/vial; 20mg/vial
    Market StatusPrescription
    CompanyBedford; Hospira; Teva Pharms Usa; Sun Pharma Global; Mustafa Nevzat; Agila Speclts

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Neuromuscular Nondepolarizing Agents

    Drugs that interrupt transmission at the skeletal neuromuscular junction without causing depolarization of the motor end plate. They prevent acetylcholine from triggering muscle contraction and are used as muscle relaxants during electroshock treatments, in convulsive states, and as anesthesia adjuvants. (See all compounds classified as Neuromuscular Nondepolarizing Agents.)

    Nicotinic Antagonists

    Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses. (See all compounds classified as Nicotinic Antagonists.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Nondepolarizing Neuromuscular Blocker [EPC]; Neuromuscular Nondepolarizing Blockade [PE]

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MALPENSA","customer":"PRATHYAK LABORATORIES PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.18","actualQuantity":"0.18","unit":"KGS","unitRateFc":"26000","totalValueFC":"4773.4","currency":"USD","unitRateINR":"2224345.5","date":"06-Aug-2024","totalValueINR":"400382.19","totalValueInUsd":"4773.4","indian_port":"Hyderabad Air","hs_no":"29333990","bill_no":"4904619","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"SEDE LEGALE: VIA DEL VECCHIOPOLITECNICO, 9 - 20121 MILANO (MI)ITALY IT","customerAddress":"Plot No.4C, MN science & technology biotech park phase-I"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727202600,"product":"VECURONIUM BROMIDE - RIDUZIONE 100% (CAS NO. 50700-72-6) (SAMPLES FREE OF CHARGE)","address":"GROUND FLOOR,1ST PRABHAT NAGAR","city":"MUMBAI ,MAHARASHTRA","supplier":"CURIA","supplierCountry":"ITALY","foreign_port":"SEGRATE AIRPRT MILAN","customer":"CIRON GROUP","customerCountry":"INDIA","quantity":"0.02","actualQuantity":"0.015","unit":"KGS","unitRateFc":"21000","totalValueFC":"321.6","currency":"USD","unitRateINR":"1796586.7","date":"25-Sep-2024","totalValueINR":"26948.8","totalValueInUsd":"321.6","indian_port":"Bombay Air","hs_no":"29319090","bill_no":"5792209","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"SEGRATE AIRPRT MILAN","supplierAddress":"VIA DEL VECCHIO POLITECNICO 9 20121 MILANO , ITALY SDNF Italy","customerAddress":"GROUND FLOOR,1ST PRABHAT NAGAR"}]
    05-Jun-2021
    25-Sep-2024
    KGS
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    ABOUT THIS PAGE

    Vecuronium Bromide Manufacturers

    A Vecuronium Bromide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Vecuronium Bromide, including repackagers and relabelers. The FDA regulates Vecuronium Bromide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Vecuronium Bromide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Vecuronium Bromide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Vecuronium Bromide Suppliers

    A Vecuronium Bromide supplier is an individual or a company that provides Vecuronium Bromide active pharmaceutical ingredient (API) or Vecuronium Bromide finished formulations upon request. The Vecuronium Bromide suppliers may include Vecuronium Bromide API manufacturers, exporters, distributors and traders.

    click here to find a list of Vecuronium Bromide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Vecuronium Bromide USDMF

    A Vecuronium Bromide DMF (Drug Master File) is a document detailing the whole manufacturing process of Vecuronium Bromide active pharmaceutical ingredient (API) in detail. Different forms of Vecuronium Bromide DMFs exist exist since differing nations have different regulations, such as Vecuronium Bromide USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Vecuronium Bromide DMF submitted to regulatory agencies in the US is known as a USDMF. Vecuronium Bromide USDMF includes data on Vecuronium Bromide's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Vecuronium Bromide USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Vecuronium Bromide suppliers with USDMF on PharmaCompass.

    Vecuronium Bromide JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Vecuronium Bromide Drug Master File in Japan (Vecuronium Bromide JDMF) empowers Vecuronium Bromide API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Vecuronium Bromide JDMF during the approval evaluation for pharmaceutical products. At the time of Vecuronium Bromide JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Vecuronium Bromide suppliers with JDMF on PharmaCompass.

    Vecuronium Bromide WC

    A Vecuronium Bromide written confirmation (Vecuronium Bromide WC) is an official document issued by a regulatory agency to a Vecuronium Bromide manufacturer, verifying that the manufacturing facility of a Vecuronium Bromide active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Vecuronium Bromide APIs or Vecuronium Bromide finished pharmaceutical products to another nation, regulatory agencies frequently require a Vecuronium Bromide WC (written confirmation) as part of the regulatory process.

    click here to find a list of Vecuronium Bromide suppliers with Written Confirmation (WC) on PharmaCompass.

    Vecuronium Bromide NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Vecuronium Bromide as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Vecuronium Bromide API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Vecuronium Bromide as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Vecuronium Bromide and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Vecuronium Bromide NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Vecuronium Bromide suppliers with NDC on PharmaCompass.

    Vecuronium Bromide GMP

    Vecuronium Bromide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Vecuronium Bromide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Vecuronium Bromide GMP manufacturer or Vecuronium Bromide GMP API supplier for your needs.

    Vecuronium Bromide CoA

    A Vecuronium Bromide CoA (Certificate of Analysis) is a formal document that attests to Vecuronium Bromide's compliance with Vecuronium Bromide specifications and serves as a tool for batch-level quality control.

    Vecuronium Bromide CoA mostly includes findings from lab analyses of a specific batch. For each Vecuronium Bromide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Vecuronium Bromide may be tested according to a variety of international standards, such as European Pharmacopoeia (Vecuronium Bromide EP), Vecuronium Bromide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Vecuronium Bromide USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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