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    Chemistry

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    Also known as: 152-11-4, Verapamil hcl, Manidon, Cordilox, Calcan hydrochloride, Verelan
    Molecular Formula
    C27H39ClN2O4
    Molecular Weight
    491.1  g/mol
    InChI Key
    DOQPXTMNIUCOSY-UHFFFAOYSA-N
    FDA UNII
    V3888OEY5R
    Verapamil Hydrochloride
    A calcium channel blocker that is a class IV anti-arrhythmia agent.
    1 2D Structure

    Verapamil Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride
    2.1.2 InChI
    InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H
    2.1.3 InChI Key
    DOQPXTMNIUCOSY-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    V3888OEY5R
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Calan

    2. Cordilox

    3. Dexverapamil

    4. Falicard

    5. Finoptin

    6. Hydrochloride, Verapamil

    7. Iproveratril

    8. Isoptin

    9. Isoptine

    10. Izoptin

    11. Lekoptin

    12. Verapamil

    2.3.2 Depositor-Supplied Synonyms

    1. 152-11-4

    2. Verapamil Hcl

    3. Manidon

    4. Cordilox

    5. Calcan Hydrochloride

    6. Verelan

    7. (+/-)-verapamil Hydrochloride

    8. Cardibeltin

    9. Isoptin

    10. Calan

    11. 23313-68-0

    12. Verapamil (hydrochloride)

    13. Cardiabeltin

    14. Cardioprotect

    15. Veroptinstada

    16. Berkatens

    17. Calaptin

    18. Cardiagutt

    19. Caveril

    20. Civicor

    21. Coraver

    22. Corpamil

    23. Dignover

    24. Durasoptin

    25. Geangin

    26. Harteze

    27. Hexasoptin

    28. Hormitol

    29. Ikapress

    30. Inselon

    31. Isoptino

    32. Izoptin

    33. Jenapamil

    34. Lodixal

    35. Magotiron

    36. Praecicor

    37. Robatelan

    38. Vasomil

    39. Vasopten

    40. Verabeta

    41. Veracor

    42. Verahexal

    43. Veraloc

    44. Veramex

    45. Veramil

    46. Verapin

    47. Verasal

    48. Verasifar

    49. Veratensin

    50. Verdilac

    51. Vetrimil

    52. Akilen

    53. Elthon

    54. Flamon

    55. Ikacor

    56. Quasar

    57. Univer

    58. Univex

    59. Vortac

    60. Anpec

    61. Ormil

    62. Rapam

    63. Verapamil Ebewe

    64. Verapamil Riker

    65. Verapamil Verla

    66. Civicor Retard

    67. Isoptin Retard

    68. Manidon Retard

    69. Vera-sanorania

    70. Verapamil Acis

    71. Verapamil Atid

    72. Novo-veramil

    73. Verapamil Basics

    74. Verapamil Nordic

    75. Verapamil-abz

    76. Novapamyl Lp

    77. Verapamil Al

    78. Verapamil Nm

    79. Verapamil Pb

    80. Verapamil Sr

    81. Verapamyl Hydrochloride

    82. Apo-verap

    83. Cordilox Sr

    84. Dilacoran Hta

    85. Veracaps Sr

    86. Verapamil Msd

    87. Arpamyl Lp

    88. Hexasoptin Retard

    89. Isoptin Sr

    90. Nu-verap

    91. Verapamil Henning

    92. Verelan Sr

    93. Covera-hs

    94. Covera

    95. Calan Sr

    96. Verapamil Injection

    97. Verapamil Nm Pharma

    98. Calaptin 240 Sr

    99. Verapress 240 Sr

    100. Mfcd00055208

    101. 5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile Hydrochloride

    102. Nsc-272366

    103. Nsc-657799

    104. Mls000069485

    105. V3888oey5r

    106. Nsc657799

    107. Lu-20175

    108. Smr000059109

    109. 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Hydrochloride

    110. 5-[n-(3,4-dimethoxyphenylethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile Hydrochloride

    111. ( Inverted Exclamation Marka)-verapamil Hydrochlorid

    112. Verapamil Chloridrate

    113. D-365 Hydrochloride

    114. Iproveratril Hydrochloride

    115. 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride

    116. 5-[(3,4-dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxy Phenyl)-2-isopropylvaleronitrile Hydrochloride

    117. Nsc272366

    118. Sr-01000000050

    119. Einecs 205-800-5

    120. Nsc 272366

    121. Unii-v3888oey5r

    122. Lu 20175

    123. C27h38n2o4.hcl

    124. Verapamil, Hcl

    125. Verapamil-d7 Hcl

    126. Prestwick_440

    127. Vasolan (tn)

    128. Verelan (tn)

    129. Covera-hs (tn)

    130. Calan (tn)

    131. Isotopin Hydrochloride

    132. Verapamil Hydrochloride [usan:usp:jan]

    133. Verapamili Hydrochloridum

    134. Opera_id_1210

    135. ()-verapamil Hydrochlorid

    136. Cas-152-11-4

    137. (y)-verapamil Hydrochloride

    138. (?)-verapamil Hydrochloride

    139. Chembl1280

    140. Dsstox_cid_14095

    141. Dsstox_rid_79114

    142. Verapamil Hydrochloride,(s)

    143. Dsstox_gsid_34095

    144. Schembl33296

    145. 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile Monohydrochloride

    146. Benzeneacetonitrile, Alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-, Monohydrochloride

    147. Mls001055442

    148. Mls002222213

    149. (+-)-verapamil Hydrochloride

    150. Spectrum2300307

    151. Dtxsid2034095

    152. Hms1568m04

    153. Hms1922j16

    154. Pharmakon1600-02300307

    155. Bcp06465

    156. Hy-a0064

    157. Tox21_201180

    158. Tox21_501237

    159. Verapamil Hydrochloride [mi]

    160. Ccg-39491

    161. Nsc759589

    162. S4202

    163. Verapamil Hydrochloride (jp17/usp)

    164. Verapamil Hydrochloride [jan]

    165. Verapamil Hydrochloride [hsdb]

    166. Verapamil Hydrochloride [usan]

    167. Akos005267117

    168. Ac-8483

    169. Cs-1685

    170. Lp01237

    171. Nsc-759589

    172. Verapamil Hydrochloride [mart.]

    173. Verapamil Hydrochloride [vandf]

    174. Verapamil Hydrochloride [usp-rs]

    175. Verapamil Hydrochloride [who-dd]

    176. Verapamil Hydrochloride [who-ip]

    177. Ncgc00024710-03

    178. Ncgc00094479-01

    179. Ncgc00094479-02

    180. Ncgc00094479-03

    181. Ncgc00094479-04

    182. Ncgc00094479-05

    183. Ncgc00258732-01

    184. Ncgc00261922-01

    185. (+-)-5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile Monohydrochloride

    186. 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile Hydrochloride

    187. 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl]methylamino}-2-(methy Lethyl)pentanenitrile, Chloride

    188. Ac-16228

    189. As-16018

    190. Benzeneacetonitrile, Alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-, Monohydrochloride, (+-)-

    191. Bv164516

    192. Sy073165

    193. Valeronitrile, 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-, Monohydrochloride

    194. Eu-0101237

    195. Ft-0603360

    196. Ft-0630593

    197. Ft-0655647

    198. Ft-0675800

    199. Sw196662-4

    200. V0118

    201. Verapamil Hydrochloride [ep Impurity]

    202. Verapamil Hydrochloride [orange Book]

    203. Tarka Component Verapamil Hydrochloride

    204. Verapamil Hydrochloride [ep Monograph]

    205. D00619

    206. D78147

    207. D88195

    208. V 4629

    209. Verapamil Hydrochloride [usp Monograph]

    210. ( Inverted Question Mark)-verapamil Hydrochloride

    211. Verapamil Hydrochloride Component Of Tarka

    212. Verapamili Hydrochloridum [who-ip Latin]

    213. 152v114

    214. A816666

    215. Q-201923

    216. Sr-01000000050-2

    217. Sr-01000000050-4

    218. (+/-)-verapamil, Hydrochloride - Cas 152-11-4

    219. Q27291481

    220. Sr-01000000050-11

    221. Z2210978706

    222. (+/-)-verapamil Hydrochloride, >=99% (titration), Powder

    223. Verapamil Hydrochloride 1.0 Mg/ml In Methanol (as Free Base)

    224. Verapamil Hydrochloride, European Pharmacopoeia (ep) Reference Standard

    225. Verapamil Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    226. (+/-)-5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile Monohydrochloride

    227. (+/-)-verapamil Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

    228. 2-(3,4-dimethoxyphenyl)-5-[[2-(3,4-dimethoxyphenyl)-ethyl](methyl)amino]-2-isopropylpentanenitrile Hydrochloride

    229. 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-propan-2-yl-pentanenitrile Hydrochloride

    230. 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile Hydrochloride

    231. 5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrilehydrochloride

    232. 5-[(3,4-dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile Hydrochloride

    233. Alpha-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-alpha-(1-methylethyl) Benzeneacetonitrile Hydrochloride

    234. Alpha-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile Hydrochloride (1:1)

    235. Benzeneacetonitrile, .alpha.-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-.alpha.-(1-methylethyl)-, Monohydrochloride, (+/-)-

    236. Benzeneacetonitrile,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-.alpha.-(1-methylethyl)-, Monohydrochloride

    237. Verapamil Hydrochloride Solution, 1.0 Mg/ml In Methanol (as Free Base), Ampule Of 1 Ml, Certified Reference Material

    2.4 Create Date
    2005-03-26
    3 Chemical and Physical Properties
    Molecular Weight 491.1 g/mol
    Molecular Formula C27H39ClN2O4
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count13
    Exact Mass490.2598354 g/mol
    Monoisotopic Mass490.2598354 g/mol
    Topological Polar Surface Area64 Ų
    Heavy Atom Count34
    Formal Charge0
    Complexity606
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameVerapamil hydrochloride
    Drug LabelVerelan (verapamil hydrochloride capsules) is a calcium ion influx inhibitor (slow channel blocker or calcium ion antagonist). Verelan is available for oral administration as a 360 mg hard gelatin capsule (lavender cap/yellow body), a 240 mg hard g...
    Active IngredientVerapamil hydrochloride
    Dosage FormTablet, extended release; Tablet; Injectable; Capsule, extended release
    RouteInjection; Oral
    Strength180mg; 200mg; 2.5mg/ml; 120mg; 300mg; 100mg; 80mg; 40mg; 240mg
    Market StatusPrescription
    CompanyHospira; Apotex; Sun Pharm Inds; Par Pharm; Watson Labs; Glenmark Generics; Ivax Sub Teva Pharms; Mylan; Heritage Pharms

    2 of 2  
    Drug NameVerapamil hydrochloride
    Drug LabelVerelan (verapamil hydrochloride capsules) is a calcium ion influx inhibitor (slow channel blocker or calcium ion antagonist). Verelan is available for oral administration as a 360 mg hard gelatin capsule (lavender cap/yellow body), a 240 mg hard g...
    Active IngredientVerapamil hydrochloride
    Dosage FormTablet, extended release; Tablet; Injectable; Capsule, extended release
    RouteInjection; Oral
    Strength180mg; 200mg; 2.5mg/ml; 120mg; 300mg; 100mg; 80mg; 40mg; 240mg
    Market StatusPrescription
    CompanyHospira; Apotex; Sun Pharm Inds; Par Pharm; Watson Labs; Glenmark Generics; Ivax Sub Teva Pharms; Mylan; Heritage Pharms

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Calcium Channel Blockers

    A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)

    Anti-Arrhythmia Agents

    Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)

    Vasodilator Agents

    Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Calcium Channel Blocker [EPC]; Cytochrome P450 3A Inhibitors [MoA]; Cytochrome P450 3A4 Inhibitors [MoA]; P-Glycoprotein Inhibitors [MoA]; Calcium Channel Antagonists [MoA]

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B5 (pt) & B6 (pt) SIPCOT"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1692642600,"product":"VERAPAMIL HYDROCHLORIDE FOR PHARMACEUTICALS USE ONLY","address":"564\/A\/22, ROAD NO. 92,JUBILEE HILL S,","city":"HYDERABAD","supplier":"RECORDATI","supplierCountry":"ITALY","foreign_port":"NA","customer":"VIATRIS","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"69.5","totalValueFC":"156446.5","currency":"EUR","unitRateINR":"6414.9","date":"22-Aug-2023","totalValueINR":"12959454.93","totalValueInUsd":"156446.5","indian_port":"JNPT\/ NHAVA SHEVA SEA","hs_no":"29269000","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"564\/A\/22, ROAD NO. 92,JUBILEE HILL S,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718994600,"product":"VERAPAMIL HYDROCHLORIDE(FOR PHARMACEUTICAL USE ONLY)","address":"564\/A\/22, ROAD NO.92","city":"HYDERABAD,ANDHRA PRADESH","supplier":"RECORDATI","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"VIATRIS","customerCountry":"INDIA","quantity":"5000.00","actualQuantity":"5000","unit":"KGS","unitRateFc":"116","totalValueFC":"647757.6","currency":"EUR","unitRateINR":"10814.9","date":"22-Jun-2024","totalValueINR":"54074429.75","totalValueInUsd":"647757.6","indian_port":"Bombay Air","hs_no":"29269000","bill_no":"4134986","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"Sede legale Via Matteo Civitali, 120148 Milano, ItaliaSDNF Italy","customerAddress":"564\/A\/22, ROAD NO.92"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722796200,"product":"VERAPAMIL HYDROCHLORIDE","address":"21-22, KALPATARU SQUARE, KONDIVITA","city":"ANDHERI (E), MUMBAI,MAHARASHTRA","supplier":"RECORDATI","supplierCountry":"ITALY","foreign_port":"ROME","customer":"TEVA PHARMACEUTICAL INDUSTRIES","customerCountry":"INDIA","quantity":"700.00","actualQuantity":"700","unit":"KGS","unitRateFc":"123","totalValueFC":"86840.6","currency":"USD","unitRateINR":"10405.8","date":"05-Aug-2024","totalValueINR":"7284060","totalValueInUsd":"86840.6","indian_port":"Bombay Air","hs_no":"29269000","bill_no":"4894828","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"ROME","supplierAddress":"Sede legale Via Matteo Civitali, 120148 Milano, Italia Milano, , Italy Italy","customerAddress":"21-22, KALPATARU SQUARE, KONDIVITA"}]
    06-Jan-2021
    30-Dec-2024
    KGS
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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    FDF Dossiers

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    01

    Cohance Lifesciences

    India
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    BIO Partnering at JPM
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothCohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

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    Regulatory Info :

    Registration Country : India

    Verapamil Hydrochloride

    Brand Name :

    Dosage Form : Sustain Release Capsule

    Dosage Strength : 120MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : India

    Cohance

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    Digital Content

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    02

    Cohance Lifesciences

    India
    arrow
    BIO Partnering at JPM
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothCohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

    Contact Supplier Contact Supplier
    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : India

    Verapamil Hydrochloride

    Brand Name :

    Dosage Form : Sustain Release Capsule

    Dosage Strength : 180MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : India

    Cohance

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    03

    Cohance Lifesciences

    India
    arrow
    BIO Partnering at JPM
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothCohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

    Contact Supplier Contact Supplier
    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : India

    Verapamil Hydrochloride

    Brand Name :

    Dosage Form : Sustain Release Capsule

    Dosage Strength : 240MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : India

    Cohance

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

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    Corporate PDF

    04

    Cohance Lifesciences

    India
    arrow
    BIO Partnering at JPM
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothCohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

    Contact Supplier Contact Supplier
    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : India

    Verapamil Hydrochloride

    Brand Name :

    Dosage Form : Sustain Release Capsule

    Dosage Strength : 360MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : India

    Cohance

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    Digital Content

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    Corporate PDF

    05

    Strides Pharma Science

    India
    arrow
    BIO Partnering at JPM
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothStrides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

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    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : RX

    Registration Country : USA

    VERAPAMIL HYDROCHLORIDE

    Brand Name : VERAPAMIL HYDROCHLORIDE

    Dosage Form : TABLET, EXTENDED RELEASE;ORAL

    Dosage Strength : 120MG

    Packaging :

    Approval Date : 1999-05-25

    Application Number : 75072

    Regulatory Info : RX

    Registration Country : USA

    Strides Pharma Science

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    Virtual Booth

    Digital Content

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    06

    Strides Pharma Science

    India
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    BIO Partnering at JPM
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothStrides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

    Contact Supplier Contact Supplier
    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : RX

    Registration Country : USA

    VERAPAMIL HYDROCHLORIDE

    Brand Name : VERAPAMIL HYDROCHLORIDE

    Dosage Form : TABLET, EXTENDED RELEASE;ORAL

    Dosage Strength : 240MG

    Packaging :

    Approval Date : 1999-05-25

    Application Number : 75072

    Regulatory Info : RX

    Registration Country : USA

    Strides Pharma Science

    Portfolio PDF

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    Virtual Booth

    Digital Content

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    07

    Actavis Inc

    Ireland
    BIO Partnering at JPM
    Not Confirmed
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    Actavis Inc

    Ireland
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    BIO Partnering at JPM
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
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    Regulatory Info : RX

    Registration Country : USA

    VERAPAMIL HYDROCHLORIDE

    Brand Name : VERAPAMIL HYDROCHLORIDE

    Dosage Form : TABLET;ORAL

    Dosage Strength : 120MG

    Packaging :

    Approval Date : 1986-10-01

    Application Number : 70994

    Regulatory Info : RX

    Registration Country : USA

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    08

    Azurity Pharma

    U.S.A
    BIO Partnering at JPM
    Not Confirmed
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    Azurity Pharma

    U.S.A
    arrow
    BIO Partnering at JPM
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
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    Regulatory Info : RX

    Registration Country : USA

    VERAPAMIL HYDROCHLORIDE

    Brand Name : VERELAN

    Dosage Form : CAPSULE, EXTENDED RELEASE;ORAL

    Dosage Strength : 180MG

    Packaging :

    Approval Date : 1992-01-09

    Application Number : 19614

    Regulatory Info : RX

    Registration Country : USA

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    09

    Pfizer Inc

    U.S.A
    BIO Partnering at JPM
    Not Confirmed
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    Pfizer Inc

    U.S.A
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    BIO Partnering at JPM
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
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    Regulatory Info : DISCN

    Registration Country : USA

    VERAPAMIL HYDROCHLORIDE

    Brand Name : CALAN SR

    Dosage Form : TABLET, EXTENDED RELEASE;ORAL

    Dosage Strength : 240MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    Packaging :

    Approval Date : 1986-12-16

    Application Number : 19152

    Regulatory Info : DISCN

    Registration Country : USA

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    10

    Smith & Kenner Pharmaceuticals

    India
    BIO Partnering at JPM
    Not Confirmed
    arrow

    Smith & Kenner Pharmaceuticals

    India
    arrow
    BIO Partnering at JPM
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : India

    Verapamil Hydrochloride

    Brand Name :

    Dosage Form : Film Coated Tablet

    Dosage Strength : 40MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : India

    blank

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    Only 10 entries up to this point, click to access all click full view read-more
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    DRUG PRODUCT COMPOSITIONS

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    DOSAGE - TABLET;ORAL - 120MG **Federal Regist...DOSAGE - TABLET;ORAL - 120MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 18817

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    DOSAGE - TABLET;ORAL - 80MG **Federal Registe...DOSAGE - TABLET;ORAL - 80MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 18817

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    DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 120M...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 120MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 19152

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    DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 180M...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 180MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 19152

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    DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 240M...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 240MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 19152

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 120...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 120MG

    USFDA APPLICATION NUMBER - 19614

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 180...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 180MG

    USFDA APPLICATION NUMBER - 19614

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 240...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 240MG

    USFDA APPLICATION NUMBER - 19614

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 360...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 360MG

    USFDA APPLICATION NUMBER - 19614

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 100...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 100MG

    USFDA APPLICATION NUMBER - 20943

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 200...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 200MG

    USFDA APPLICATION NUMBER - 20943

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 300...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 300MG

    USFDA APPLICATION NUMBER - 20943

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    ABOUT THIS PAGE

    Verapamil Hydrochloride Manufacturers

    A Verapamil Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Verapamil Hydrochloride, including repackagers and relabelers. The FDA regulates Verapamil Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Verapamil Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Verapamil Hydrochloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Verapamil Hydrochloride Suppliers

    A Verapamil Hydrochloride supplier is an individual or a company that provides Verapamil Hydrochloride active pharmaceutical ingredient (API) or Verapamil Hydrochloride finished formulations upon request. The Verapamil Hydrochloride suppliers may include Verapamil Hydrochloride API manufacturers, exporters, distributors and traders.

    click here to find a list of Verapamil Hydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Verapamil Hydrochloride USDMF

    A Verapamil Hydrochloride DMF (Drug Master File) is a document detailing the whole manufacturing process of Verapamil Hydrochloride active pharmaceutical ingredient (API) in detail. Different forms of Verapamil Hydrochloride DMFs exist exist since differing nations have different regulations, such as Verapamil Hydrochloride USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Verapamil Hydrochloride DMF submitted to regulatory agencies in the US is known as a USDMF. Verapamil Hydrochloride USDMF includes data on Verapamil Hydrochloride's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Verapamil Hydrochloride USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Verapamil Hydrochloride suppliers with USDMF on PharmaCompass.

    Verapamil Hydrochloride JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Verapamil Hydrochloride Drug Master File in Japan (Verapamil Hydrochloride JDMF) empowers Verapamil Hydrochloride API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Verapamil Hydrochloride JDMF during the approval evaluation for pharmaceutical products. At the time of Verapamil Hydrochloride JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Verapamil Hydrochloride suppliers with JDMF on PharmaCompass.

    Verapamil Hydrochloride KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Verapamil Hydrochloride Drug Master File in Korea (Verapamil Hydrochloride KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Verapamil Hydrochloride. The MFDS reviews the Verapamil Hydrochloride KDMF as part of the drug registration process and uses the information provided in the Verapamil Hydrochloride KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Verapamil Hydrochloride KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Verapamil Hydrochloride API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Verapamil Hydrochloride suppliers with KDMF on PharmaCompass.

    Verapamil Hydrochloride CEP

    A Verapamil Hydrochloride CEP of the European Pharmacopoeia monograph is often referred to as a Verapamil Hydrochloride Certificate of Suitability (COS). The purpose of a Verapamil Hydrochloride CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Verapamil Hydrochloride EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Verapamil Hydrochloride to their clients by showing that a Verapamil Hydrochloride CEP has been issued for it. The manufacturer submits a Verapamil Hydrochloride CEP (COS) as part of the market authorization procedure, and it takes on the role of a Verapamil Hydrochloride CEP holder for the record. Additionally, the data presented in the Verapamil Hydrochloride CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Verapamil Hydrochloride DMF.

    A Verapamil Hydrochloride CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Verapamil Hydrochloride CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Verapamil Hydrochloride suppliers with CEP (COS) on PharmaCompass.

    Verapamil Hydrochloride WC

    A Verapamil Hydrochloride written confirmation (Verapamil Hydrochloride WC) is an official document issued by a regulatory agency to a Verapamil Hydrochloride manufacturer, verifying that the manufacturing facility of a Verapamil Hydrochloride active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Verapamil Hydrochloride APIs or Verapamil Hydrochloride finished pharmaceutical products to another nation, regulatory agencies frequently require a Verapamil Hydrochloride WC (written confirmation) as part of the regulatory process.

    click here to find a list of Verapamil Hydrochloride suppliers with Written Confirmation (WC) on PharmaCompass.

    Verapamil Hydrochloride NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Verapamil Hydrochloride as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Verapamil Hydrochloride API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Verapamil Hydrochloride as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Verapamil Hydrochloride and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Verapamil Hydrochloride NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Verapamil Hydrochloride suppliers with NDC on PharmaCompass.

    Verapamil Hydrochloride GMP

    Verapamil Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Verapamil Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Verapamil Hydrochloride GMP manufacturer or Verapamil Hydrochloride GMP API supplier for your needs.

    Verapamil Hydrochloride CoA

    A Verapamil Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Verapamil Hydrochloride's compliance with Verapamil Hydrochloride specifications and serves as a tool for batch-level quality control.

    Verapamil Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Verapamil Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Verapamil Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Verapamil Hydrochloride EP), Verapamil Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Verapamil Hydrochloride USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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