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Chemistry

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Also known as: 29984-33-6, Vidarabine monophosphate, Ara-amp, Vidarabine phosphate [usan], Cl-808, 9-(5-o-phosphono-beta-d-arabinofuranosyl)adenine
Molecular Formula
C10H14N5O7P
Molecular Weight
347.22  g/mol
InChI Key
UDMBCSSLTHHNCD-UHTZMRCNSA-N
FDA UNII
106XV160TZ

Vidarabine Monophosphate
An adenosine monophosphate analog in which ribose is replaced by an arabinose moiety. It is the monophosphate ester of VIDARABINE with antiviral and possibly antineoplastic properties.
1 2D Structure

Vidarabine Monophosphate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
2.1.2 InChI
InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7+,10-/m1/s1
2.1.3 InChI Key
UDMBCSSLTHHNCD-UHTZMRCNSA-N
2.1.4 Canonical SMILES
C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O)N
2.1.5 Isomeric SMILES
C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N
2.2 Other Identifiers
2.2.1 UNII
106XV160TZ
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 9-(5-o-phosphono-beta-d-arabinofuranosyl)-9h-purin-6-amine

2. Adenine Arabinoside Monophosphate

3. Ara Amp

4. Ara-amp

5. Arabinofuranosyladenine Monophosphate

6. Monophosphate, Adenine Arabinoside

7. Monophosphate, Arabinofuranosyladenine

8. Monophosphate, Vidarabine

9. Phosphate, Vidarabine

10. Vidarabine Monophosphate

2.3.2 Depositor-Supplied Synonyms

1. 29984-33-6

2. Vidarabine Monophosphate

3. Ara-amp

4. Vidarabine Phosphate [usan]

5. Cl-808

6. 9-(5-o-phosphono-beta-d-arabinofuranosyl)adenine

7. Ci-808

8. 9h-purin-6-amine, 9-(5-o-phosphono-beta-d-arabinofuranosyl)-

9. 9-(5-o-phosphono-beta-d-arabinofuranosyl)-9h-purin-6-amine

10. Adenine-9-beta-d-arabinofuranoside-5'-monophosphate

11. Adenine Arabinoside Monophosphate

12. Vidarabine-5'-monophosphate

13. 106xv160tz

14. Arabinosyladenine Monophosphate

15. Adenine Arabinose-5'-phosphate

16. Nsc-127223

17. Araamp

18. 5'-arabinosyladenine Monophosphate

19. 9h-purin-6-amine, 9-(5-o-phosphono-b-d-arabinofuranosyl)-

20. Adenine Arabinoside 5'-monophosphate

21. D-arabinosyladenine 5'-monophosphate

22. Adenine Arabinonucleoside 5'-phosphate

23. [(2r,3s,4s,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl Dihydrogen Phosphate

24. Vidarabine Phosphate (usan)

25. 9h-purin-6-amine,9-(5-o-phosphono-b-d-arabinofuranosyl)-

26. Vidarabinemonophosphate

27. Vidarabine 5'-monophosphate

28. Einecs 249-990-8

29. Nsc 127223

30. 9h-purin-6-amine, 9-(5-o-phosphono-.beta.-d-arabinofuranosyl)-

31. Unii-106xv160tz

32. Nsc127223

33. 9-beta-d-arabinofuranosyladenine 5'-phosphate

34. 9-beta-d-arabinofuranosyladenine Monophosphate

35. Arabino-amp

36. 9-beta-d-arabinofuranosyladenine 5'-monophosphate

37. Mfcd00069723

38. 9-beta-d-arabinofuranosyladenine 5'-(dihydrogen Phosphate)

39. Adenine, 9beta-d-arabinofuranosyl-, 5'-(dihydrogen Phosphate)

40. Schembl144996

41. Chembl1230732

42. Hy-b0277a

43. Adenosine Arabinoside-5'-phosphate

44. Dtxsid401009318

45. Adenine, 9-beta-d-arabinofuranosyl-, 5'-(dihydrogen Phosphate)

46. Bcp10479

47. Zinc2126310

48. Hg1004

49. Vidarabine Phosphate [mart.]

50. Vidarabine Phosphate [who-dd]

51. Akos015915213

52. Ac-5505

53. Am84913

54. ((2r,3s,4s,5r)-5-(6-amino-9h-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl Dihydrogen Phosphate

55. [(2r,3s,4s,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl Dihydrogen Phosphate

56. As-70487

57. Ara-adenosine-5'-monophosphate (ara-amp)

58. Cs-0083442

59. D06299

60. 9-(b-d-arabinofuranosyl)adenine5'-monophosphate

61. 9-(b-d-arabinofuranosyl)adenine 5'-monophosphate

62. 9-beta-d-arabinofuranosyladenine-5'-monophosphate

63. 984a336

64. A820136

65. 9-(.beta.-d-arabinofuranosyl)adenine-5'-phosphate

66. Q6607436

67. W-202244

68. 9-beta-d-arabinofuranosyl-adenine-5'-monophosphate

69. 9h-purin-6-amine, 9-(5-o-phosphono-b-d-arabinofuranosyl)-;

70. 9-.beta.-d-arabinofuranosyladenine 5'-(dihydrogen Phosphate)

71. {[(2r,3s,4s,5r)-5-(6-amino-9h-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic Acid

72. A5o

2.4 Create Date
2005-07-12
3 Chemical and Physical Properties
Molecular Weight 347.22 g/mol
Molecular Formula C10H14N5O7P
XLogP3-3.5
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count11
Rotatable Bond Count4
Exact Mass347.06308480 g/mol
Monoisotopic Mass347.06308480 g/mol
Topological Polar Surface Area186 Ų
Heavy Atom Count23
Formal Charge0
Complexity481
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antimetabolites

Drugs that are chemically similar to naturally occurring metabolites, but differ enough to interfere with normal metabolic pathways. (From AMA Drug Evaluations Annual, 1994, p2033) (See all compounds classified as Antimetabolites.)


Antiviral Agents

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)


ABOUT THIS PAGE

Vidarabine Monophosphate Manufacturers

A Vidarabine Monophosphate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Vidarabine Monophosphate, including repackagers and relabelers. The FDA regulates Vidarabine Monophosphate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Vidarabine Monophosphate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Vidarabine Monophosphate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Vidarabine Monophosphate Suppliers

A Vidarabine Monophosphate supplier is an individual or a company that provides Vidarabine Monophosphate active pharmaceutical ingredient (API) or Vidarabine Monophosphate finished formulations upon request. The Vidarabine Monophosphate suppliers may include Vidarabine Monophosphate API manufacturers, exporters, distributors and traders.

click here to find a list of Vidarabine Monophosphate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Vidarabine Monophosphate GMP

Vidarabine Monophosphate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Vidarabine Monophosphate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Vidarabine Monophosphate GMP manufacturer or Vidarabine Monophosphate GMP API supplier for your needs.

Vidarabine Monophosphate CoA

A Vidarabine Monophosphate CoA (Certificate of Analysis) is a formal document that attests to Vidarabine Monophosphate's compliance with Vidarabine Monophosphate specifications and serves as a tool for batch-level quality control.

Vidarabine Monophosphate CoA mostly includes findings from lab analyses of a specific batch. For each Vidarabine Monophosphate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Vidarabine Monophosphate may be tested according to a variety of international standards, such as European Pharmacopoeia (Vidarabine Monophosphate EP), Vidarabine Monophosphate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Vidarabine Monophosphate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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