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Vilanterol Trifenatate

Inke Vilanterol Trifenatate

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Neuland Vilanterol Trifenatate

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xyz-pharma-m-2024-10-07

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With Fermion, start the journey of your innovative API.

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Bloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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xyz-pharma-m-2024-10-07

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CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

25 API Suppliers, 8 USDMF, 4 EU WC, 1 KDMF, 9 NDC API, 21 Listed Suppliers, $ API Reference Price

25 API Suppliers
8 USDMF
4 EU WC
1 KDMF
9 NDC API
21 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

11 Drugs in Development

11 Drugs in Development

INTERMEDIATES

10 Intermediates Suppliers

10 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

41 FDF Dossiers, 6 FDA Orange Book, 30 Europe, 5 South Africa

41 FDF Dossiers
6 FDA Orange Book
30 Europe
5 South Africa

DRUG PRODUCT COMPOSITIONS

POWDER;INHALATION - EQ 0.0625MG BASE/INH;EQ 0.025MG BASE/INH, POWDER;INHALATION - 0.05MG/INH;EQ 0.025MG BASE/INH, POWDER;INHALATION - 0.1MG/INH;EQ 0.025MG BASE/INH, POWDER;INHALATION - 0.2MG/INH;EQ 0.025MG BASE/INH

drugProductComposition
POWDER;INHALATION - EQ 0.0625MG BASE/INH;EQ 0.025MG BASE/INH
POWDER;INHALATION - 0.05MG/INH;EQ 0.025MG BASE/INH
POWDER;INHALATION - 0.1MG/INH;EQ 0.025MG BASE/INH
POWDER;INHALATION - 0.2MG/INH;EQ 0.025MG BASE/INH

RELATED EXCIPIENT COMPANIES

2 Faran Shimi Pharmaceutical, 4 Gangwal Healthcare, 1 Nanjing Well Pharmaceutical, 1 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 2 DFE Pharma, 14 Kerry, 7 Microlex e.U, 2 Pluviaendo, 1 Prachin Chemical, 1 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 2 Sigachi Industries, 1 Vasa Pharmachem

relatedExcipients
2 Faran Shimi Pharmaceutical
4 Gangwal Healthcare
1 Nanjing Well Pharmaceutical
1 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd
2 DFE Pharma
14 Kerry
7 Microlex e.U
2 Pluviaendo
1 Prachin Chemical
1 Shanghai Shenmei Pharmaceutical Technology Co., Ltd
2 Sigachi Industries
1 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

25 Fillers, Diluents & Binders, 8 Direct Compression, 8 Lubricants & Glidants, 5 Co-Processed Excipients, 4 Granulation, 1 Controlled & Modified Release, 1 Emulsifying Agents, 1 Thickeners and Stabilizers, 1 Parenteral

excipientsByApplications
25 Fillers, Diluents & Binders
8 Direct Compression
8 Lubricants & Glidants
5 Co-Processed Excipients
4 Granulation
1 Controlled & Modified Release
1 Emulsifying Agents
1 Thickeners and Stabilizers
1 Parenteral

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 42 NEWS #PharmaBuzz

media
1 DATA COMPILATION #PharmaFlow
42 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

30 Finished Drug Prices, 10 Annual Reports

globalSalesInformation
30 Finished Drug Prices
10 Annual Reports

MARKET PLACE

2 APIs

marketPlace
2 APIs

PATENTS & EXCLUSIVITIES

110 US Patents, 4 US Exclusivities

patents
110 US Patents
4 US Exclusivities

REF. STANDARDS & IMPURITIES

10 Others

otherSolutions
10 Others

Inke Vilanterol Trifenatate

Synopsis

ACTIVE PHARMA INGREDIENTS

25

API Suppliers

8

USDMF

0

CEP/COS

CEP/COS Certifications

0

JDMF

4

EU WC

1

KDMF

9

NDC API

0

VMF

21

Listed Suppliers

API REF. PRICE (USD/KG)

$

$ 223,171

MARKET PLACE

2

API

0

FDF

10INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

41

FDF Dossiers

6

FDA Orange Book

FDA (Orange Book)

30

Europe

0

Canada

0

Australia

5

South Africa

0

Listed Dossiers

11DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

10

Others

PATENTS & EXCLUSIVITIES

110

US Patents

4

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

1

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

42

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

NA

Annual Reports (USD Million)

11,206

Finished Drug Prices

38 RELATED EXCIPIENT COMPANIES

54EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 503070-58-4, Vilanterol trifenate, Vilanterol (trifenatate), Gw642444m, Unii-40aho2c6dg, Chebi:75040

Molecular Formula

C₄₄H₄₉Cl₂NO₇

Molecular Weight

774.8 g/mol

InChI Key

KLOLZALDXGTNQE-JIDHJSLPSA-N

FDA UNII

40AHO2C6DG

Vilanterol Trifenatate

1 2D Structure

Vilanterol Trifenatate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-[(1R)-2-[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexylamino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol;2,2,2-triphenylacetic acid

2.1.2 InChI

InChI=1S/C24H33Cl2NO5.C20H16O2/c25-21-6-5-7-22(26)20(21)17-32-13-12-31-11-4-2-1-3-10-27-15-24(30)18-8-9-23(29)19(14-18)16-28;21-19(22)20(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h5-9,14,24,27-30H,1-4,10-13,15-17H2;1-15H,(H,21,22)/t24-;/m0./s1

2.1.3 InChI Key

KLOLZALDXGTNQE-JIDHJSLPSA-N

2.1.4 Canonical SMILES

C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)O.C1=CC(=C(C(=C1)Cl)COCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O)Cl

2.1.5 Isomeric SMILES

C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)O.C1=CC(=C(C(=C1)Cl)COCCOCCCCCCNC[C@@H](C2=CC(=C(C=C2)O)CO)O)Cl

2.2 Other Identifiers

2.2.1 UNII

40AHO2C6DG

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 503070-58-4

2. Vilanterol Trifenate

3. Vilanterol (trifenatate)

4. Gw642444m

5. Unii-40aho2c6dg

6. Chebi:75040

7. Gw 642444m

8. Gw-642444m

9. Vilanterol (as Trifenatate)

10. 40aho2c6dg

11. Vilanterol Trifenatate [usan]

12. 4-[(1r)-2-[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexylamino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol;2,2,2-triphenylacetic Acid

13. Benzeneacetic Acid, Alpha,alpha-diphenyl-, Compd. With (alpha1r)-alpha1-[[[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexyl]amino]methyl]-4-hydroxy-1,3-benzenedimethanol (1

14. Triphenylacetic Acid-4-((1r)-2-((6-(2-((2,6-dichlorobenzyl)oxy)ethoxy)hexyl)amino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol (1:1)

15. Vilanterol Triphenylacetate

16. Gw642444 (trifenatate)

17. Schembl164639

18. Chembl1084172

19. Dtxsid80659232

20. Hms3885o21

21. Vilanterol Trifenatate [mi]

22. Amy30059

23. Bcp18862

24. Ex-a4159

25. Vilanterol Trifenatate (jan/usan)

26. Vilanterol Trifenatate [jan]

27. Hy-14300a

28. S3727

29. Ccg-270458

30. Cs-1679

31. Vilanterol Trifenatate [who-dd]

32. Vilanterol Trifenatate [orange Book]

33. D09697

34. F11535

35. A899729

36. Breo Ellipta Component Vilanterol Trifenatate

37. Anoro Ellipta Component Vilanterol Trifenatate

38. Q27145087

39. Trelegy Ellipta Component Vilanterol Trifenatate

40. Vilanterol Trifenatate Component Anoro Ellipta

41. Gw 642444x;gw-642444x;gw642444x

42. Vilanterol Trifenatate Component Of Breo Ellipta

43. Vilanterol Trifenatate Component Of Trelegy Ellipta

44. 4-((1r)-2-((6-(2-((2,6-dichlorophenyl)methoxy)ethoxy)hexyl)amino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol Triphenylacetate

45. 4-[(1r)-2-[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexylamino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol,2,2,2-triphenylacetic Acid

46. 4-{(1r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol Triphenylacetate

47. 6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}-n-{(2r)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl}hexan-1-aminium Triphenylacetate

48. Benzeneacetic Acid, Alpha,alpha-diphenyl-, Compd. With (alpha1r)-alpha1-(((6-(2-((2,6-dichlorophenyl)methoxy)ethoxy)hexyl)amino)methyl)-4-hydroxy-1,3-benzenedimethanol (1:1)

49. Triphenylacetic Acid--4-{(1r)-2-[(6-{2-[(2,6-dichlorophenyl)methoxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol (1/1)

50. Triphenylacetic Acid-4-((1r)-2-((6-(2-(2,6-dicholorobenzyl)oxy)ethoxy)hexyl)amino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol (1:1)

2.4 Create Date

2009-12-15

3 Chemical and Physical Properties

Molecular Formula	C₄₄H₄₉Cl₂NO₇
Molecular Weight	774.8 g/mol
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	20
Exact Mass	773.2886083 g/mol
Monoisotopic Mass	773.2886083 g/mol
Topological Polar Surface Area	129 Å²
Heavy Atom Count	54
Formal Charge	0
Complexity	778
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

API SUPPLIERS

01

Inke S.A

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

Inke S.A: APIs manufacturing plant.

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Spain

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CEP/COS JDMF EU-WC NDC

KDMF VMF ASMF

AUDIT

Inke Company Banner

Product Web Link

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02

Neuland Laboratories

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

Neuland Laboratories- A dedicated 100% API provider.

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India

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USDMF

CEP/COS JDMF EU-WC

NDC KDMF VMF ASMF

AUDIT

Product Web Link

Digital Content

03

LGM Pharma

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

LGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

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U.S.A

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04

Metrochem API Private Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

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India

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05

Vamsi Labs

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Vamsi Labs is one of the major manufacturers of Anti-asthmatic, Anti-migraine & Anti-psychotic APIs.

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India

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06

TAPI Technology & API Services

Israel

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CPhI WW Frankfurt

TAPI offers customized CDMO Solutions for API development and manufacturing services.

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Israel

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Corporate PDF

07

GSK

United Kingdom

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

GSK

United Kingdom

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Not Confirmed

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08

Lupin Ltd

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

09

MSN Laboratories

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

10

Sterling Chemical Malta

Malta

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Not Confirmed

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API Reference Price

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ROAD,, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Import","activeIngredients":"VILANTEROL","year":"2021","qtr":"Q1","strtotime":1614018600,"product":"RE-IMPORT FOR REPROCESSING : VILANTEROL TRIFENATATE IH GRADE: IH","address":"FLAT,NO.505, 5TH FLR.,UNIQUE TOWER,S.V.ROAD,NR.KAMATH CLUB,GOREGAON(W)","city":"MUMBAI, MAHARASHTRA","supplier":"HOVIONE","supplierCountry":"INDIA","foreign_port":"","customer":"MELODY HEALTHCARE PVT LTD","customerCountry":"INDIA","quantity":"3.29","actualQuantity":"3.288","unit":"KGS","unitRateFc":"175638.7","totalValueFC":"584585.6","currency":"USD","unitRateINR":"12944571.2","date":"23-Feb-2021","totalValueINR":"42561750","totalValueInUsd":"584585.6","indian_port":"BOMBAY AIR","hs_no":"29072990","bill_no":"2873297","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"","supplierAddress":"","customerAddress":"FLAT,NO.505, 5TH FLR.,UNIQUE TOWER,S.V.ROAD,NR.KAMATH CLUB,GOREGAON(W)"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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DOSAGE - POWDER;INHALATION - EQ 0.0625MG BASE...DOSAGE - POWDER;INHALATION - EQ 0.0625MG BASE/INH;EQ 0.025MG BASE/INH

USFDA APPLICATION NUMBER - 203975

DOSAGE - POWDER;INHALATION - 0.05MG/INH;EQ 0....DOSAGE - POWDER;INHALATION - 0.05MG/INH;EQ 0.025MG BASE/INH

USFDA APPLICATION NUMBER - 204275

DOSAGE - POWDER;INHALATION - 0.1MG/INH;EQ 0.0...DOSAGE - POWDER;INHALATION - 0.1MG/INH;EQ 0.025MG BASE/INH

USFDA APPLICATION NUMBER - 204275

DOSAGE - POWDER;INHALATION - 0.2MG/INH;EQ 0.0...DOSAGE - POWDER;INHALATION - 0.2MG/INH;EQ 0.025MG BASE/INH

USFDA APPLICATION NUMBER - 204275

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