All Manufacturers, Suppliers, Distributors and Exporters of Viloxazine Hydrochloride with approved FDA Orange Book of Finished Dosage Form listed on PharmaCompass.com

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Chemistry

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Also known as: 35604-67-2, 2-((2-ethoxyphenoxy)methyl)morpholine hydrochloride, Viloxazine hcl, Vivalan, Emovit, Vicilan
Molecular Formula
C13H20ClNO3
Molecular Weight
273.75  g/mol
InChI Key
HJOCKFVCMLCPTP-UHFFFAOYSA-N
FDA UNII
OQW30I1332

Viloxazine Hydrochloride
A morpholine derivative used as an antidepressant. It is similar in action to IMIPRAMINE.
1 2D Structure

Viloxazine Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[(2-ethoxyphenoxy)methyl]morpholine;hydrochloride
2.1.2 InChI
InChI=1S/C13H19NO3.ClH/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11;/h3-6,11,14H,2,7-10H2,1H3;1H
2.1.3 InChI Key
HJOCKFVCMLCPTP-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCOC1=CC=CC=C1OCC2CNCCO2.Cl
2.2 Other Identifiers
2.2.1 UNII
OQW30I1332
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Emovit

2. Ici-58,834

3. Ici58,834

4. Viloxazine

5. Viloxazine Hydrochloride, (r)-isomer

6. Viloxazine Hydrochloride, (s)-isomer

7. Viloxazine Oxalate (1:1)

8. Viloxazine, (+-)-isomer

9. Viloxazine, (r)-isomer

10. Viloxazine, (s)-isomer

11. Vivalan

2.3.2 Depositor-Supplied Synonyms

1. 35604-67-2

2. 2-((2-ethoxyphenoxy)methyl)morpholine Hydrochloride

3. Viloxazine Hcl

4. Vivalan

5. Emovit

6. Vicilan

7. 2-[(2-ethoxyphenoxy)methyl]morpholine Hydrochloride

8. Rac Viloxazine Hydrochloride

9. Viloxacina Clorhidrato

10. Ici 58,834

11. Viloxazine Hydrochloride [usan]

12. 2-((2-ethoxyphenoxy)methyl)morpholinehydrochloride

13. 2-[(2-ethoxyphenoxy)methyl]morpholine;hydrochloride

14. 2-((o-ethoxyphenoxy)methyl)morpholine Hydrochloride

15. Spn-812

16. Oqw30i1332

17. Qelbree

18. 2-[(2-ethoxy Phenoxy)methyl]morpholine Hydrochloride

19. Morpholine, 2-((2-ethoxyphenoxy)methyl)-, Hydrochloride

20. Morpholine, 2-[(2-ethoxyphenoxy)methyl]-, Hydrochloride

21. Ici-58834

22. Viloxazine Hydrochloride (usan)

23. Ccris 1915

24. Viloxacina Clorhidrato [spanish]

25. Einecs 252-638-6

26. Unii-oqw30i1332

27. Prestwick_734

28. Vivalan (tn)

29. Cloridrato De Viloxazina

30. 2-(2-ethoxyphenoxymethyl)tetrahydro-1,4-oxazine Hydrochloride

31. Chlorhydrate De Viloxazine

32. 2-(2-ethoxyphenoxymethyl)-2,3,5,6-tetrahydro-1,4-oxazine Hydrochloride

33. Dsstox_cid_31511

34. Dsstox_rid_97396

35. Dsstox_gsid_57722

36. Schembl300741

37. Chembl2106483

38. Dtxsid8057722

39. Glxc-25714

40. Tox21_113955

41. Viloxazine Hydrochloride [mi]

42. Akos015847050

43. At27980

44. Ccg-220828

45. Viloxazine Hydrochloride [mart.]

46. Ncgc00262964-01

47. Viloxazine Hydrochloride [who-dd]

48. Cas-35604-67-2

49. A6217

50. Ft-0675815

51. Ft-0675816

52. Ft-0675817

53. Ft-0675818

54. Ft-0675819

55. Viloxazine Hydrochloride [orange Book]

56. D02572

57. 2-(o-ethoxyphenoxymethyl)morpholine Hydrochloride

58. 604e672

59. Sr-01000872636

60. Sr-01000872636-1

61. W-110863

62. 2-(2-ethoxy-phenoxymethyl)-morpholine; Hydrochloride

63. 2-[(2-ethoxyphenoxy)-methyl]morpholine Hydrochloride

64. Q27285797

65. 2-(2-ethoxy-phenoxymethyl)-tetra-hydro-1,4-oxazine Hydrochloride

66. (+/-)-morpholine, 2-((2-ethoxyphenoxy)methyl)-, Hydrochloride

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 273.75 g/mol
Molecular Formula C13H20ClNO3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass273.1131712 g/mol
Monoisotopic Mass273.1131712 g/mol
Topological Polar Surface Area39.7 Ų
Heavy Atom Count18
Formal Charge0
Complexity213
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antidepressive Agents, Second-Generation

A structurally and mechanistically diverse group of drugs that are not tricyclics or monoamine oxidase inhibitors. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake. (See all compounds classified as Antidepressive Agents, Second-Generation.)


Adrenergic Uptake Inhibitors

Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (ANTIDEPRESSIVE AGENTS, TRICYCLIC) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. (See all compounds classified as Adrenergic Uptake Inhibitors.)


4.2 FDA Pharmacological Classification
4.2.1 Pharmacological Classes
Cytochrome P450 2B6 Inhibitors [MoA]; Cytochrome P450 2D6 Inhibitors [MoA]; Cytochrome P450 3A4 Inhibitors [MoA]; Norepinephrine Reuptake Inhibitor [EPC]; Norepinephrine Uptake Inhibitors [MoA]; Cytochrome P450 1A2 Inhibitors [MoA]

API SUPPLIERS

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01

ChemWerth Inc

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Virtual BoothChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

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Biophore India Pharmaceuticals Pvt...

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBiophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

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Biophore

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Metrochem API Private Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothMetrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

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Macsen Labs

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothMacsen Labs, a leader in Chemistry since 1952, specializing in APIs, specialty and fine chemicals, and dyes.

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Zydus Lifesciences

India

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Zydus Lifesciences

India

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Lee Pharma

India

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India

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Viyash Life Sciences

India

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Amsa Spa

Italy

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Maithri Drugs

India

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Maithri Drugs

India

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16-Aug-2024
16-Aug-2024
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