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    Chemistry

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    Also known as: 143-67-9, Velban, Velsar, Vinblastine (sulfate), Velbe, Exal
    Molecular Formula
    C46H60N4O13S
    Molecular Weight
    909.1  g/mol
    InChI Key
    KDQAABAKXDWYSZ-PNYVAJAMSA-N
    FDA UNII
    N00W22YO2B
    Vinblastine Sulfate
    Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
    1 2D Structure

    Vinblastine Sulfate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate;sulfuric acid
    2.1.2 InChI
    InChI=1S/C46H58N4O9.H2O4S/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7;1-5(2,3)4/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3;(H2,1,2,3,4)/t28-,37-,38+,39+,42-,43+,44+,45-,46-;/m0./s1
    2.1.3 InChI Key
    KDQAABAKXDWYSZ-PNYVAJAMSA-N
    2.1.4 Canonical SMILES
    CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
    2.1.5 Isomeric SMILES
    CC[C@@]1(C[C@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    N00W22YO2B
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Cellblastin

    2. Lemblastine

    3. Sulfate, Vinblastine

    4. Velban

    5. Velbe

    6. Vinblastin Hexal

    7. Vinblastina Lilly

    8. Vinblastine

    9. Vinblastinsulfat-gry

    10. Vincaleukoblastine

    2.3.2 Depositor-Supplied Synonyms

    1. 143-67-9

    2. Velban

    3. Velsar

    4. Vinblastine (sulfate)

    5. Velbe

    6. Exal

    7. Vlb Monosulfate

    8. Alkaban-aq

    9. 29060-le

    10. Vinblastine Sulphate

    11. Vincaleukoblastine,sulfate(1:1)

    12. Nsc-49842

    13. Mls000863275

    14. Vincaleukoblastine, Sulfate (1:1) (salt)

    15. N00w22yo2b

    16. Belvan, Vlb

    17. 29060le

    18. Smr000058844

    19. Vincaleucoblastine Sulfate

    20. Dsstox_cid_27831

    21. Dsstox_rid_82594

    22. Dsstox_gsid_47853

    23. Uniblastin

    24. Rozevin Sulfate

    25. 29060 Le

    26. Cas-18556-44-0

    27. Vincaleukoblastine, Sulfate

    28. Unii-n00w22yo2b

    29. Ccris 2584

    30. Vinblastinesulfate

    31. Vinblastini Sulfas

    32. Chembl378544

    33. Ncgc00095285-01

    34. Einecs 205-606-0

    35. Vinblastine Sulfate [usan:usp:jan]

    36. Opera_id_960

    37. Ai3-52943

    38. Ncgc00181127-01

    39. Schembl3549

    40. Mls000069550

    41. Mls002153253

    42. Mls002207069

    43. Vinblastine Sulfate [mi]

    44. Vinblastine Sulfate [jan]

    45. Dtxsid601017133

    46. Hms2235e07

    47. Hms3403n09

    48. Vinblastine Sulfate [iarc]

    49. Vinblastine Sulfate [usan]

    50. Vinblastine Sulfate [vandf]

    51. Vinblastine Sulfate [mart.]

    52. Tox21_111498

    53. Tox21_112735

    54. Ac-821

    55. Vinblastine Sulfate [usp-rs]

    56. Vinblastine Sulfate [who-dd]

    57. Vinblastine Sulfate [who-ip]

    58. Akos015960580

    59. Tox21_111498_1

    60. Tox21_112735_1

    61. Cs-1365

    62. Ncgc00263548-01

    63. Ncgc00344583-01

    64. Vinblastine Sulfate [orange Book]

    65. Hy-13780

    66. Vinblastine Sulfate [ep Monograph]

    67. Vinblastini Sulfas [who-ip Latin]

    68. Vinblastine Sulfate [usp Monograph]

    69. N2255

    70. 143v679

    71. Sr-01000000155

    72. Vinblastine Sulfate Salt, Powder, >=96% (hplc)

    73. Sr-01000000155-7

    74. Q27077057

    75. Vinblastine Sulfate, European Pharmacopoeia (ep) Reference Standard

    76. Vinblastine Sulfate, United States Pharmacopeia (usp) Reference Standard

    77. Methyl (1r,9r,10s,11r,12r,19r)-11-(acetyloxy)-12-ethyl-4-[(13s,15r,17s)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0?,??.0?,??]nonadeca-4(12),5(10),6,8-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0?,?.0?,?.0??,??]nonadeca-2(7),3,5,13-tetraene-10-carboxylate; Sulfuric Acid

    78. Methyl (3ar,3a1r,4r,5s,5ar,10br)-4-acetoxy-3a-ethyl-9-((5s,7r,9s)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2h-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1h-indolizino[8,1-cd]carbazole-5-carboxylate Sulfate

    2.3.3 Other Synonyms

    1. Vincaleukoblastine Sulfate

    2. Vinblastine Sulphate

    3. Cellblastin

    2.4 Create Date
    2005-06-29
    3 Chemical and Physical Properties
    Molecular Weight 909.1 g/mol
    Molecular Formula C46H60N4O13S
    Hydrogen Bond Donor Count5
    Hydrogen Bond Acceptor Count16
    Rotatable Bond Count10
    Exact Mass908.38775915 g/mol
    Monoisotopic Mass908.38775915 g/mol
    Topological Polar Surface Area237 Ų
    Heavy Atom Count64
    Formal Charge0
    Complexity1780
    Isotope Atom Count0
    Defined Atom Stereocenter Count9
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameVinblastine sulfate
    PubMed HealthVinblastine
    Drug LabelVinblastine sulfate is the salt of an alkaloid extracted from Vinca rosea Linn., a common flowering herb known as the periwinkle (more properly known as Catharanthus roseus G. Don). Previously, the generic name was vincaleukoblastine, abbreviated VLB...
    Active IngredientVinblastine sulfate
    Dosage FormInjectable
    RouteInjection
    Strength10mg/vial; 1mg/ml
    Market StatusPrescription
    CompanyFresenius Kabi Usa; Eurohlth Intl

    2 of 2  
    Drug NameVinblastine sulfate
    PubMed HealthVinblastine
    Drug LabelVinblastine sulfate is the salt of an alkaloid extracted from Vinca rosea Linn., a common flowering herb known as the periwinkle (more properly known as Catharanthus roseus G. Don). Previously, the generic name was vincaleukoblastine, abbreviated VLB...
    Active IngredientVinblastine sulfate
    Dosage FormInjectable
    RouteInjection
    Strength10mg/vial; 1mg/ml
    Market StatusPrescription
    CompanyFresenius Kabi Usa; Eurohlth Intl

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Antineoplastic Agents, Phytogenic

    Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity. (See all compounds classified as Antineoplastic Agents, Phytogenic.)

    Tubulin Modulators

    Agents that interact with TUBULIN to inhibit or promote polymerization of MICROTUBULES. (See all compounds classified as Tubulin Modulators.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Vinca Alkaloids [CS]; Vinca Alkaloid [EPC]

    API Reference Price

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NO.9 LINK RD"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1630261800,"product":"VINBLASTINE SULFATE","address":"SCO.88, SECTOR 44-C,","city":"CHANDIGARH (UT)","supplier":"GD NAYO LIGHT ","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"HEALTH BIOTECH","customerCountry":"INDIA","quantity":"0.09","actualQuantity":"85","unit":"GMS","unitRateFc":"107","totalValueFC":"9221.6","currency":"USD","unitRateINR":"8046.4","date":"30-Aug-2021","totalValueINR":"683944","totalValueInUsd":"9221.6","indian_port":"DELHI AIR","hs_no":"29349990","bill_no":"5242500","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"","customerAddress":"SCO.88, SECTOR 44-C,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1653849000,"product":"VINBLASTINE SULFATE IP (LIST 3 SR.NO.77)","address":"1101, 11TH FLOOR, DHUKKA CHAMBERS OFF PODDAR PARK ROAD, MALAD EAST","city":"MUMBAI","supplier":"GUANGDONG JIAHONG COMPANY","supplierCountry":"CHINA","foreign_port":"NA","customer":"UNICHEMIE INTERNATIONAL PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.50","actualQuantity":"500","unit":"GMS","unitRateFc":"106","totalValueFC":"53901.3","currency":"USD","unitRateINR":"8331.6","date":"30-May-2022","totalValueINR":"4165800","totalValueInUsd":"53901.3","indian_port":"BOMBAY AIR","hs_no":"29398000","bill_no":"8895549","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"1101, 11TH FLOOR, DHUKKA CHAMBERS OFF PODDAR PARK ROAD, MALAD EAST"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1670351400,"product":"22-OXOVINCALEUKOBLASTINE SULFATE (ORGANIC CHEMICAL)(FOR LABORATORY ANALYTICAL TESTING PURPOSE R AND D USE ONLY)","address":"17 LOTUS BUSINESS PARK,NEW LINK RD ANDHERI W","city":"MUMBAI,MAHARASHTRA","supplier":"HABO HONG KONG ","supplierCountry":"CHINA","foreign_port":"NA","customer":"CLEARSYNTH LABS LIMITED","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"5","unit":"GMS","unitRateFc":"200","totalValueFC":"995.1","currency":"USD","unitRateINR":"16400","date":"07-Dec-2022","totalValueINR":"82000","totalValueInUsd":"995.1","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"3628122","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"17 LOTUS BUSINESS PARK,NEW LINK RD ANDHERI W"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1679855400,"product":"VINBLASTINE SULFATE IP (LIST 3 SR.NO.77)","address":"1101, 11TH FLOOR, DHUKKA CHAMBERS OFF PODDAR PARK ROAD, MALAD EAST","city":"MUMBAI","supplier":"GUANGDONG JIAHONG COMPANY","supplierCountry":"CHINA","foreign_port":"NA","customer":"UNICHEMIE INTERNATIONAL PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.20","actualQuantity":"200","unit":"GMS","unitRateFc":"107.5","totalValueFC":"21878.9","currency":"USD","unitRateINR":"8997.8","date":"27-Mar-2023","totalValueINR":"1799550","totalValueInUsd":"21878.9","indian_port":"BOMBAY AIR","hs_no":"29398000","bill_no":"5240752","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"1101, 11TH FLOOR, DHUKKA CHAMBERS OFF PODDAR PARK ROAD, MALAD EAST"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1686767400,"product":"VINBLASTINE SULFATE IP (LIST 3 SR.NO.77)","address":"1101, 11TH FLOOR, DHUKKA CHAMBERS OFF PODDAR PARK ROAD, MALAD EAST","city":"MUMBAI","supplier":"GUANGDONG JIAHONG COMPANY","supplierCountry":"CHINA","foreign_port":"NA","customer":"UNICHEMIE INTERNATIONAL PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"100","unit":"GMS","unitRateFc":"107.5","totalValueFC":"10907.4","currency":"USD","unitRateINR":"8965.6","date":"15-Jun-2023","totalValueINR":"896550.403","totalValueInUsd":"10907.4","indian_port":"BOMBAY AIR","hs_no":"29398000","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"1101, 11TH FLOOR, DHUKKA CHAMBERS OFF PODDAR PARK ROAD, MALAD EAST"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1688149800,"product":"VINBLASTINE SULFATE IP (LIST 3 SR.NO.77)","address":"1101, 11TH FLOOR, DHUKKA CHAMBERS OFF PODDAR PARK ROAD, MALAD EAST","city":"MUMBAI","supplier":"GUANGDONG JIAHONG COMPANY","supplierCountry":"CHINA","foreign_port":"NA","customer":"UNICHEMIE INTERNATIONAL PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.15","actualQuantity":"150","unit":"GMS","unitRateFc":"107.5","totalValueFC":"16293.8","currency":"USD","unitRateINR":"8928.1","date":"01-Jul-2023","totalValueINR":"1339181.613","totalValueInUsd":"16293.8","indian_port":"BOMBAY AIR","hs_no":"29398000","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"1101, 11TH FLOOR, DHUKKA CHAMBERS OFF PODDAR PARK ROAD, MALAD EAST"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1695753000,"product":"22-OXOVINCALEUKOBLASTINE SULFATE SALT","address":"8-2-293\/82\/2\/76A, MLA COLONY,","city":"HILLS, HYDERABAD, TS","supplier":"M\/S. S &Y BIOCHEM CO., LTD","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"SESA CHEM INDIA ","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"0.1","unit":"KGS","unitRateFc":"170000","totalValueFC":"17213.4","currency":"USD","unitRateINR":"14288500","date":"27-Sep-2023","totalValueINR":"1428850","totalValueInUsd":"17213.4","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"8028602","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"NO. 1501, SHUNHE STREET NORTHLANSHAN DISTRICT, LINYI CITY,SHANDONG PROVINCE, CHINA CN","customerAddress":"8-2-293\/82\/2\/76A, MLA COLONY,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1702837800,"product":"VINBLASTINE SULFATE IP","address":"1101, 11TH FLOOR, DHUKKA CHAMBERS","city":"MUMBAI","supplier":"GUANGDONG JIAHONG COMPANY","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"UNICHEMIE INTERNATIONAL PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"100","unit":"GMS","unitRateFc":"107.5","totalValueFC":"10886.5","currency":"USD","unitRateINR":"9062.3","date":"18-Dec-2023","totalValueINR":"906225","totalValueInUsd":"10886.5","indian_port":"Bombay Air","hs_no":"29398000","bill_no":"9285435","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"18\/F HAIJIAO BUILDING,NO.93 TIANHEROAD, GUANGZHOU,CHINASDNF China","customerAddress":"1101, 11TH FLOOR, DHUKKA CHAMBERS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1709145000,"product":"22-OXOVINCALEUKOBLASTINE SULFATE SALT","address":"8-2-293\/82\/2\/76A, MLA COLONY,","city":"HILLS, HYDERABAD, TS","supplier":"M\/S. S &Y BIOCHEM CO., LTD","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"SESA CHEM INDIA ","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"0.1","unit":"KGS","unitRateFc":"168000","totalValueFC":"16987.5","currency":"USD","unitRateINR":"14095200","date":"29-Feb-2024","totalValueINR":"1409520","totalValueInUsd":"16987.5","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"2368937","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"NO. 1501, SHUNHE STREET NORTHLANSHAN DISTRICT, LINYI CITY,SHANDONG PROVINCE, CHINA CN","customerAddress":"8-2-293\/82\/2\/76A, MLA COLONY,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718130600,"product":"VINBLASTINE SULFATE IP (LIST 3 SR.NO.77)","address":"1101, 11TH FLOOR, DHUKKA CHAMBERS","city":"MUMBAI","supplier":"GUANGDONG JIAHONG COMPANY","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"UNICHEMIE INTERNATIONAL PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"100","unit":"GMS","unitRateFc":"107.5","totalValueFC":"10855.7","currency":"USD","unitRateINR":"9062.3","date":"12-Jun-2024","totalValueINR":"906225","totalValueInUsd":"10855.7","indian_port":"Bombay Air","hs_no":"29398000","bill_no":"3951863","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"18\/F HAIJIAO BUILDING,NO.93 TIANHEROAD, GUANGZHOU,CHINASDNF China","customerAddress":"1101, 11TH FLOOR, DHUKKA CHAMBERS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723573800,"product":"VINBLASTINE SULFATE (QTY: 2 X 50MG, VALUE USD: 600\/EACH) (FOC)","address":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,","city":"TURKAPALLY(V),SHAMEERPET, HYDERABAD","supplier":"UNITED STATES PHARMACOPEIAL","supplierCountry":"INDIA","foreign_port":"WASHINGTON, DULLES I","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0001","unit":"KGS","unitRateFc":"12000000","totalValueFC":"1252.2","currency":"USD","unitRateINR":"1050331500","date":"14-Aug-2024","totalValueINR":"105033.15","totalValueInUsd":"1252.2","indian_port":"Hyderabad Air","hs_no":"29397900","bill_no":"5055144","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON, DULLES I","supplierAddress":"7135 ENGLISH MUFFIN WAY FREDERICK,MD,US 21704,UNITED STATES OF AMERICASDNF United States","customerAddress":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,"}]
    31-May-2021
    14-Aug-2024
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    ABOUT THIS PAGE

    Vinblastine Sulfate Manufacturers

    A Vinblastine Sulfate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Vinblastine Sulfate, including repackagers and relabelers. The FDA regulates Vinblastine Sulfate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Vinblastine Sulfate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Vinblastine Sulfate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Vinblastine Sulfate Suppliers

    A Vinblastine Sulfate supplier is an individual or a company that provides Vinblastine Sulfate active pharmaceutical ingredient (API) or Vinblastine Sulfate finished formulations upon request. The Vinblastine Sulfate suppliers may include Vinblastine Sulfate API manufacturers, exporters, distributors and traders.

    click here to find a list of Vinblastine Sulfate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Vinblastine Sulfate USDMF

    A Vinblastine Sulfate DMF (Drug Master File) is a document detailing the whole manufacturing process of Vinblastine Sulfate active pharmaceutical ingredient (API) in detail. Different forms of Vinblastine Sulfate DMFs exist exist since differing nations have different regulations, such as Vinblastine Sulfate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Vinblastine Sulfate DMF submitted to regulatory agencies in the US is known as a USDMF. Vinblastine Sulfate USDMF includes data on Vinblastine Sulfate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Vinblastine Sulfate USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Vinblastine Sulfate suppliers with USDMF on PharmaCompass.

    Vinblastine Sulfate JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Vinblastine Sulfate Drug Master File in Japan (Vinblastine Sulfate JDMF) empowers Vinblastine Sulfate API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Vinblastine Sulfate JDMF during the approval evaluation for pharmaceutical products. At the time of Vinblastine Sulfate JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Vinblastine Sulfate suppliers with JDMF on PharmaCompass.

    Vinblastine Sulfate CEP

    A Vinblastine Sulfate CEP of the European Pharmacopoeia monograph is often referred to as a Vinblastine Sulfate Certificate of Suitability (COS). The purpose of a Vinblastine Sulfate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Vinblastine Sulfate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Vinblastine Sulfate to their clients by showing that a Vinblastine Sulfate CEP has been issued for it. The manufacturer submits a Vinblastine Sulfate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Vinblastine Sulfate CEP holder for the record. Additionally, the data presented in the Vinblastine Sulfate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Vinblastine Sulfate DMF.

    A Vinblastine Sulfate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Vinblastine Sulfate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Vinblastine Sulfate suppliers with CEP (COS) on PharmaCompass.

    Vinblastine Sulfate WC

    A Vinblastine Sulfate written confirmation (Vinblastine Sulfate WC) is an official document issued by a regulatory agency to a Vinblastine Sulfate manufacturer, verifying that the manufacturing facility of a Vinblastine Sulfate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Vinblastine Sulfate APIs or Vinblastine Sulfate finished pharmaceutical products to another nation, regulatory agencies frequently require a Vinblastine Sulfate WC (written confirmation) as part of the regulatory process.

    click here to find a list of Vinblastine Sulfate suppliers with Written Confirmation (WC) on PharmaCompass.

    Vinblastine Sulfate NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Vinblastine Sulfate as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Vinblastine Sulfate API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Vinblastine Sulfate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Vinblastine Sulfate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Vinblastine Sulfate NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Vinblastine Sulfate suppliers with NDC on PharmaCompass.

    Vinblastine Sulfate GMP

    Vinblastine Sulfate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Vinblastine Sulfate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Vinblastine Sulfate GMP manufacturer or Vinblastine Sulfate GMP API supplier for your needs.

    Vinblastine Sulfate CoA

    A Vinblastine Sulfate CoA (Certificate of Analysis) is a formal document that attests to Vinblastine Sulfate's compliance with Vinblastine Sulfate specifications and serves as a tool for batch-level quality control.

    Vinblastine Sulfate CoA mostly includes findings from lab analyses of a specific batch. For each Vinblastine Sulfate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Vinblastine Sulfate may be tested according to a variety of international standards, such as European Pharmacopoeia (Vinblastine Sulfate EP), Vinblastine Sulfate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Vinblastine Sulfate USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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