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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

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API

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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FDF Dossiers

FDF Dossiers

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FDA Orange Book

FDA (Orange Book)

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

PATENTS & EXCLUSIVITIES

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US Patents

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US Exclusivities

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Health Canada Patents

DIGITAL CONTENT

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Data Compilation #PharmaFlow

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Stock Recap #PipelineProspector

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News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

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Annual Reports

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0RELATED EXCIPIENT COMPANIES

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Chemistry

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Also known as: (-)-eburnamonine, 4880-88-0, Vincamone, Eburnamonine, L-eburnamonine, Eburnal
Molecular Formula
C19H22N2O
Molecular Weight
294.4  g/mol
InChI Key
WYJAPUKIYAZSEM-MOPGFXCFSA-N
FDA UNII
64UB2942IE

Vinburnine
vinburnine is a natural product found in Kopsia pauciflora, Aspidosperma quebracho-blanco, and other organisms with data available.
1 2D Structure

Vinburnine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-one
2.1.2 InChI
InChI=1S/C19H22N2O/c1-2-19-9-5-10-20-11-8-14-13-6-3-4-7-15(13)21(16(22)12-19)17(14)18(19)20/h3-4,6-7,18H,2,5,8-12H2,1H3/t18-,19+/m1/s1
2.1.3 InChI Key
WYJAPUKIYAZSEM-MOPGFXCFSA-N
2.1.4 Canonical SMILES
CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2
2.1.5 Isomeric SMILES
CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2
2.2 Other Identifiers
2.2.1 UNII
64UB2942IE
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (-)-eburnamonine

2. Cervoxan

3. Eburnamonine

4. Eburnamonine Monohydrochloride, (3alpha,16alpha)-isomer

5. Eburnamonine Phosphate, (3alpha,16alpha)-isomer

6. Eburnamonine, (3alpha,16alpha)-isomer

2.3.2 Depositor-Supplied Synonyms

1. (-)-eburnamonine

2. 4880-88-0

3. Vincamone

4. Eburnamonine

5. L-eburnamonine

6. Eburnal

7. Eburnamonine (-)

8. Vinburnine [inn]

9. Vincanorine

10. Dl-eburnamonine

11. Eburnamonine (-)-form

12. (+/-)-vincamone

13. (+/-)-eburnamonine

14. Vinburnine, (+/-)-

15. Ch-846

16. Eburnamonine (+/-)-form [mi]

17. 2580-88-3

18. Nsc-322920

19. Eburnamenin-14(15h)-one, (+/-)-

20. Chebi:4740

21. G54d0hmy25

22. 3.alpha.,16.alpha.-eburnamonine

23. 64ub2942ie

24. Vinburnine (inn)

25. Nsc322920

26. Eburnal Ritardo

27. Cis-vincamone

28. Dsstox_cid_25119

29. Dsstox_rid_80685

30. Dsstox_gsid_45119

31. (15s,19s)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-one

32. Vincamona [spanish]

33. Vinburnina

34. Vinburninum

35. Vincamona

36. Vinburninum [inn-latin]

37. Vinburnina [inn-spanish]

38. (-)-eburnamonina

39. (-)-eburnamonina [spanish]

40. (-)-vincamone

41. (3?,16?)-eburnamenin-14(15h)-one

42. 3-alpha,16-alpha-eburnamonine

43. Mls000758467

44. Einecs 225-490-5

45. Ch 846

46. Nsc 322920

47. 3alpha,16alpha-eburnamonine

48. Unii-g54d0hmy25

49. Eburnalritardo

50. Unii-64ub2942ie

51. (3alpha,16alpha)-eburnamenin-14(15h)-one

52. (3-alpha,16-alpha)-eburnamin-14(15h)-one

53. Eburnamin-14(15h)-one, (3-alpha,16-alpha)-

54. Ncgc00014750-02

55. Cervoxan (tn)

56. Prestwick_189

57. Cas-4880-88-0

58. Spectrum_000379

59. Prestwick0_000607

60. Prestwick1_000607

61. Prestwick2_000607

62. Prestwick3_000607

63. Spectrum2_001504

64. Spectrum3_001199

65. Spectrum4_000751

66. Spectrum5_000938

67. Vinburnine [mart.]

68. Ncistruc1_000941

69. Ncistruc2_000870

70. Vinburnine [who-dd]

71. Bspbio_000514

72. Bspbio_002877

73. Gtpl345

74. Kbiogr_001102

75. Kbioss_000859

76. Mls002153906

77. Divk1c_000411

78. Schembl456385

79. Spbio_001547

80. Spbio_002733

81. Bpbio1_000566

82. Megxp0_001871

83. Chembl1892145

84. Dtxsid6045119

85. Acon1_000004

86. Hms501e13

87. Kbio1_000411

88. Kbio2_000859

89. Kbio2_003427

90. Kbio2_005995

91. Kbio3_002377

92. Ninds_000411

93. Hms1569j16

94. Hms2096j16

95. Hms2233k13

96. Hms3713j16

97. Act03251

98. Bcp02373

99. Hy-b1180

100. Tox21_110060

101. Ccg-36740

102. Eburnamonine (-)-form [mi]

103. Nci322920

104. S5681

105. Zinc19796061

106. Akos015896486

107. Tox21_110060_1

108. Cs-4789

109. Db13793

110. Fd10193

111. Idi1_000411

112. Ncgc00262533-02

113. Ncgc00262533-03

114. Ac-26459

115. Bs-16859

116. Nci60_002800

117. Smr001233255

118. Sbi-0051740.p002

119. Eburnamenin-14(15h)-one, (3a,16a)-

120. C09149

121. D08676

122. A871877

123. Q2526386

124. Brd-k40227168-001-03-8

125. Brd-k40227168-001-06-1

126. (3alpha,16alpha)-eburnamenin-14(15h)-one, Vincamone]

127. Ncgc00262533-03_c19h22n2o_(3alpha,16alpha)-14,15-dihydroeburnamenin-14-one

128. (31s,6as)-6a-ethyl-31,4,5,6,6a,7-hexahydro-1h-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridin-8(2h)-one

129. (41s,13as)-13a-ethyl-2,3,5,6,13,13a-hexahydro-1h-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridin-12(41h)-one

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 294.4 g/mol
Molecular Formula C19H22N2O
XLogP33
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass294.173213330 g/mol
Monoisotopic Mass294.173213330 g/mol
Topological Polar Surface Area25.2 Ų
Heavy Atom Count22
Formal Charge0
Complexity492
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Vasodilator Agents

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)


4.2 ATC Code

C - Cardiovascular system

C04 - Peripheral vasodilators

C04A - Peripheral vasodilators

C04AX - Other peripheral vasodilators

C04AX17 - Vinburnine


API SUPPLIERS

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ABOUT THIS PAGE

Vinburnine Manufacturers

A Vinburnine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Vinburnine, including repackagers and relabelers. The FDA regulates Vinburnine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Vinburnine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Vinburnine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Vinburnine Suppliers

A Vinburnine supplier is an individual or a company that provides Vinburnine active pharmaceutical ingredient (API) or Vinburnine finished formulations upon request. The Vinburnine suppliers may include Vinburnine API manufacturers, exporters, distributors and traders.

click here to find a list of Vinburnine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Vinburnine GMP

Vinburnine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Vinburnine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Vinburnine GMP manufacturer or Vinburnine GMP API supplier for your needs.

Vinburnine CoA

A Vinburnine CoA (Certificate of Analysis) is a formal document that attests to Vinburnine's compliance with Vinburnine specifications and serves as a tool for batch-level quality control.

Vinburnine CoA mostly includes findings from lab analyses of a specific batch. For each Vinburnine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Vinburnine may be tested according to a variety of international standards, such as European Pharmacopoeia (Vinburnine EP), Vinburnine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Vinburnine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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