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Chemistry

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Also known as: 934240-30-9, Vixotrigine, Cnv1014802, Gsk1014802, Cnv-1014802, Gsk-1014802
Molecular Formula
C18H19FN2O2
Molecular Weight
314.4  g/mol
InChI Key
JESCETIFNOFKEU-SJORKVTESA-N
FDA UNII
QQS4J85K6Y

Vixotrigine
Raxatrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
1 2D Structure

Vixotrigine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,5R)-5-[4-[(2-fluorophenyl)methoxy]phenyl]pyrrolidine-2-carboxamide
2.1.2 InChI
InChI=1S/C18H19FN2O2/c19-15-4-2-1-3-13(15)11-23-14-7-5-12(6-8-14)16-9-10-17(21-16)18(20)22/h1-8,16-17,21H,9-11H2,(H2,20,22)/t16-,17+/m1/s1
2.1.3 InChI Key
JESCETIFNOFKEU-SJORKVTESA-N
2.1.4 Canonical SMILES
C1CC(NC1C2=CC=C(C=C2)OCC3=CC=CC=C3F)C(=O)N
2.1.5 Isomeric SMILES
C1C[C@H](N[C@H]1C2=CC=C(C=C2)OCC3=CC=CC=C3F)C(=O)N
2.2 Other Identifiers
2.2.1 UNII
QQS4J85K6Y
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Biib074

2. Cnv1014802

3. Vixotrigine

2.3.2 Depositor-Supplied Synonyms

1. 934240-30-9

2. Vixotrigine

3. Cnv1014802

4. Gsk1014802

5. Cnv-1014802

6. Gsk-1014802

7. Biib074

8. Cnv 1014802

9. Biib-074

10. Vixotrigine [usan]

11. Raxatrigine (gsk1014802)

12. (2s,5r)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide

13. Gsk 1014802

14. Qqs4j85k6y

15. Gsk1014802(cnv1014802)

16. 934240-30-9 (free Base).

17. 2-pyrrolidinecarboxamide, 5-(4-((2-fluorophenyl)methoxy)phenyl)-, (2s,5r)-

18. 2-pyrrolidinecarboxamide, 5-[4-[(2-fluorophenyl)methoxy]phenyl]-, (2s,5r)-

19. Raxatrigine [usan]

20. Gsk2

21. Unii-qqs4j85k6y

22. Biib 074

23. (2s,5r)-5-[4-[(2-fluorophenyl)methoxy]phenyl]pyrrolidine-2-carboxamide

24. (2s,5r)-5-(4-((2-fluorophenyl)methoxy)phenyl)pyrrolidine-2-carboxamide

25. Biib 074,vixotrigine

26. Vixotrigine [inn]

27. Vixotrigine (usan/inn)

28. Vixotrigine [who-dd]

29. Schembl310473

30. Chembl3544913

31. Dtxsid901031867

32. (5r)-5-(4-{[(2-fluorophenyl)methyl]oxy}phenyl)-l-prolinamide

33. Ex-a2232

34. Bdbm50505255

35. Zinc34892269

36. Akos027324140

37. Db11706

38. Ncgc00386656-01

39. Ac-31665

40. As-56210

41. Hy-12796

42. Cnv1014802; Gsk-1014802; Raxatrigine

43. D11179

44. N11408

45. A857124

46. (5r)-5-(4-[2-fluorobenzyloxy]phenyl)-l-prolinamide

47. Q18386159

48. (2s,5r)-5-(4-(2-fluorobenzyloxy)phenyl)pyrrolidine-2-carboxamide

49. (5r)-5-{4-[(2-fluorobenzyl)oxy]phenyl}-l-prolinamide;cnv1014802

2.4 Create Date
2007-04-30
3 Chemical and Physical Properties
Molecular Weight 314.4 g/mol
Molecular Formula C18H19FN2O2
XLogP32.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass314.14305602 g/mol
Monoisotopic Mass314.14305602 g/mol
Topological Polar Surface Area64.4 Ų
Heavy Atom Count23
Formal Charge0
Complexity399
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Vixotrigine Manufacturers

A Vixotrigine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Vixotrigine, including repackagers and relabelers. The FDA regulates Vixotrigine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Vixotrigine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Vixotrigine Suppliers

A Vixotrigine supplier is an individual or a company that provides Vixotrigine active pharmaceutical ingredient (API) or Vixotrigine finished formulations upon request. The Vixotrigine suppliers may include Vixotrigine API manufacturers, exporters, distributors and traders.

Vixotrigine GMP

Vixotrigine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Vixotrigine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Vixotrigine GMP manufacturer or Vixotrigine GMP API supplier for your needs.

Vixotrigine CoA

A Vixotrigine CoA (Certificate of Analysis) is a formal document that attests to Vixotrigine's compliance with Vixotrigine specifications and serves as a tool for batch-level quality control.

Vixotrigine CoA mostly includes findings from lab analyses of a specific batch. For each Vixotrigine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Vixotrigine may be tested according to a variety of international standards, such as European Pharmacopoeia (Vixotrigine EP), Vixotrigine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Vixotrigine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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