Find Vociprotafib manufacturers, exporters & distributors on PharmaCompass

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Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: Rmc-4630, Rmc4630, 2172652-48-9, Shp2-in-7, Sar442720, Sar-442720
Molecular Formula
C20H27ClN6O2S
Molecular Weight
451.0  g/mol
InChI Key
HISJAYUQVHMWTA-BLLLJJGKSA-N

Vociprotafib
1 2D Structure

Vociprotafib

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[6-(2-amino-3-chloropyridin-4-yl)sulfanyl-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-5-methylpyrazin-2-yl]methanol
2.1.2 InChI
InChI=1S/C20H27ClN6O2S/c1-11-19(30-14-3-6-24-17(23)15(14)21)26-13(9-28)18(25-11)27-7-4-20(5-8-27)10-29-12(2)16(20)22/h3,6,12,16,28H,4-5,7-10,22H2,1-2H3,(H2,23,24)/t12-,16+/m0/s1
2.1.3 InChI Key
HISJAYUQVHMWTA-BLLLJJGKSA-N
2.1.4 Canonical SMILES
CC1C(C2(CCN(CC2)C3=NC(=C(N=C3CO)SC4=C(C(=NC=C4)N)Cl)C)CO1)N
2.1.5 Isomeric SMILES
C[C@H]1[C@H](C2(CCN(CC2)C3=NC(=C(N=C3CO)SC4=C(C(=NC=C4)N)Cl)C)CO1)N
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. Rmc-4630

2. Rmc4630

3. 2172652-48-9

4. Shp2-in-7

5. Sar442720

6. Sar-442720

7. [6-(2-amino-3-chloropyridin-4-yl)sulfanyl-3-[(3s,4s)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-5-methylpyrazin-2-yl]methanol

8. Vociprotafib [inn]

9. Unii-c4ybf9170l

10. C4ybf9170l

11. Schembl19785097

12. Gtpl12067

13. Ptpn11 Inhibitor Rmc-4630

14. Rmc 4630 [who-dd]

15. Glxc-25735

16. Ex-a5486

17. Nsc839698

18. Nsc-839698

19. Hy-141523

20. Cs-0179559

21. Compound A-290 [wo2018013597a1]

22. (6-((2-amino-3-chloropyridin-4-yl)sulfanyl)-3-((3s,4s)-4-amino- 3-methyl-2-oxa-8-azaspiro(4.5)decan-8-yl)- 5-methylpyrazin-2-yl)methanol

23. 2-pyrazinemethanol, 6-((2-amino-3-chloro-4-pyridinyl)thio)-3-((3s,4s)-4-amino-3-methyl-2-oxa-8-azaspiro(4.5)dec-8-yl)-5-methyl-

2.3 Create Date
2018-06-23
3 Chemical and Physical Properties
Molecular Weight 451.0 g/mol
Molecular Formula C20H27ClN6O2S
XLogP31.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count4
Exact Mass450.1604730 g/mol
Monoisotopic Mass450.1604730 g/mol
Topological Polar Surface Area149 Ų
Heavy Atom Count30
Formal Charge0
Complexity584
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Vociprotafib Manufacturers

A Vociprotafib manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Vociprotafib, including repackagers and relabelers. The FDA regulates Vociprotafib manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Vociprotafib API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Vociprotafib Suppliers

A Vociprotafib supplier is an individual or a company that provides Vociprotafib active pharmaceutical ingredient (API) or Vociprotafib finished formulations upon request. The Vociprotafib suppliers may include Vociprotafib API manufacturers, exporters, distributors and traders.

Vociprotafib GMP

Vociprotafib Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Vociprotafib GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Vociprotafib GMP manufacturer or Vociprotafib GMP API supplier for your needs.

Vociprotafib CoA

A Vociprotafib CoA (Certificate of Analysis) is a formal document that attests to Vociprotafib's compliance with Vociprotafib specifications and serves as a tool for batch-level quality control.

Vociprotafib CoA mostly includes findings from lab analyses of a specific batch. For each Vociprotafib CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Vociprotafib may be tested according to a variety of international standards, such as European Pharmacopoeia (Vociprotafib EP), Vociprotafib JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Vociprotafib USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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