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    Also known as: 129-06-6, Sodium warfarin, Jantoven, Aldocumar, Athrombin, Marevan
    Molecular Formula
    C19H15NaO4
    Molecular Weight
    330.3  g/mol
    InChI Key
    KYITYFHKDODNCQ-UHFFFAOYSA-M
    FDA UNII
    6153CWM0CL
    Warfarin Sodium
    An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.
    1 2D Structure

    Warfarin Sodium

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;2-oxo-3-(3-oxo-1-phenylbutyl)chromen-4-olate
    2.1.2 InChI
    InChI=1S/C19H16O4.Na/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22;/h2-10,15,21H,11H2,1H3;/q;+1/p-1
    2.1.3 InChI Key
    KYITYFHKDODNCQ-UHFFFAOYSA-M
    2.1.4 Canonical SMILES
    CC(=O)CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)[O-].[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    6153CWM0CL
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2h-1-benzopyran-2-one

    2. Aldocumar

    3. Apo-warfarin

    4. Coumadin

    5. Coumadine

    6. Gen-warfarin

    7. Marevan

    8. Potassium, Warfarin

    9. Sodium, Warfarin

    10. Tedicumar

    11. Warfant

    12. Warfarin

    13. Warfarin Potassium

    2.3.2 Depositor-Supplied Synonyms

    1. 129-06-6

    2. Sodium Warfarin

    3. Jantoven

    4. Aldocumar

    5. Athrombin

    6. Marevan

    7. Zoocoumarin Sodium Salt

    8. Warfarin Sodium Salt

    9. Apo-warfarin

    10. Warfarin (sodium)

    11. Sodium 2-oxo-3-(3-oxo-1-phenylbutyl)-2h-chromen-4-olate

    12. Warfarin Sodium [usp]

    13. 3-(alpha-acetonylbenzyl)-4-hydroxycoumarin Sodium Salt

    14. 6153cwm0cl

    15. Warfarin Sodium Clathrate

    16. 2h-1-benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, Sodium Salt

    17. 67430-45-9

    18. Coumadine

    19. Dicusat

    20. Marevam

    21. Orfarin

    22. Tintorane

    23. Varfine

    24. Warcoumin

    25. Warfarin Sodium (usp)

    26. Warfilone

    27. Simarc

    28. Coumadin Sodium

    29. Sodium Coumadin

    30. Uniwarfin

    31. Ratsul Soluble

    32. Coumadan Sodico

    33. Coumafene Sodium

    34. Warfarinsodium

    35. Sodium;2-oxo-3-(3-oxo-1-phenylbutyl)chromen-4-olate

    36. Warfarin, Sodium Salt

    37. Caswell No. 903a

    38. Warfarin-sodium

    39. (+-)-warfarin Sodium

    40. Warfarin, Sodium Deriv.

    41. Einecs 204-929-4

    42. 3-(3-oxo-1-phenylbutyl)-4-sodiooxy-2h-1-benzopyran-2-one

    43. Epa Pesticide Chemical Code 086003

    44. Unii-6153cwm0cl

    45. Warfarinum Natricum

    46. Coumadin (tn)

    47. Jantoven (tn)

    48. Einecs 226-909-4

    49. Sodium, ((3-(alpha-acetonylbenzyl)-2-oxo-2h-1-benzopyran-4-yl)oxy)-

    50. Warfarin Sodium Clatharate

    51. Schembl7826

    52. Dsstox_cid_15010

    53. Dsstox_rid_79236

    54. Dsstox_gsid_35010

    55. Mls001074341

    56. Warfarin Sodium [vandf]

    57. Chembl1200879

    58. Dtxsid7035010

    59. Warfarin Sodium [mart.]

    60. Hy-b0687a

    61. Warfarin Sodium [who-dd]

    62. Warfarin Sodium [who-ip]

    63. Warfarin Sodium Salt [mi]

    64. Coumarin, 3-(alpha-acetonylbenzyl)-4-hydroxy-, Sodium Salt

    65. Hms2233p10

    66. Hms3259g13

    67. Hms3369m10

    68. Bcp20702

    69. Tox21_301545

    70. Bdbm50248297

    71. Warfarin Sodium [orange Book]

    72. Akos015951251

    73. Akos015955387

    74. Warfarin Sodium [ep Monograph]

    75. Ac-8078

    76. Cs-w019743

    77. Nc00490

    78. Warfarin Sodium [usp Monograph]

    79. Ncgc00255556-01

    80. Ac-19972

    81. Cas-129-06-6

    82. Smr000058849

    83. Warfarinum Natricum [who-ip Latin]

    84. W0005

    85. Warfarin Sodium (contains Isopropyl Alcohol)

    86. D00564

    87. O12075

    88. A805899

    89. J-005647

    90. Sodium Warfarin;warf42 Sodium; Athrombine-k Sodium

    91. Q27263296

    92. 3-(alpha-acetonylbenzyl)-4-hydroxycoumarin Sodiuim Salt

    93. 4-hydroxy-3-(3-oxo-1-phenylbutyl)coumarin Sodium Salt

    94. Sodium 2-oxo-3-(3-oxo-1-phenylbutyl)-1-benzopyran-4-olate

    95. 3-(.alpha.-acetonylbenzyl)-4-hydroxycoumarin Sodium Salt

    96. Sodium 2-oxidanylidene-3-(3-oxidanylidene-1-phenyl-butyl)chromen-4-olate

    97. 2h-1-benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, Sodium Salt (1:1)

    2.4 Create Date
    2007-07-11
    3 Chemical and Physical Properties
    Molecular Weight 330.3 g/mol
    Molecular Formula C19H15NaO4
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count4
    Exact Mass330.08680324 g/mol
    Monoisotopic Mass330.08680324 g/mol
    Topological Polar Surface Area66.4 Ų
    Heavy Atom Count24
    Formal Charge0
    Complexity508
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 4  
    Drug NameJantoven
    PubMed HealthWarfarin
    Drug ClassesAnticoagulant
    Drug LabelJantovenTablets (crystalline warfarin sodium) is an anticoagulant which acts by inhibiting vitamin K-dependent coagulation factors. Chemically, it is 3-(and is a racemic mixture of the R- and S-enantiomers. Crystalline warfarin sodium is an isopropan...
    Active IngredientWarfarin sodium
    Dosage FormTablet
    RouteOral
    Strength2.5mg; 7.5mg; 1mg; 5mg; 4mg; 6mg; 2mg; 10mg; 3mg
    Market StatusPrescription
    CompanyUsl Pharma

    2 of 4  
    Drug NameWarfarin sodium
    Drug LabelWarfarin sodium tablet (crystalline warfarin sodium) is an anticoagulant, which acts by inhibiting vitamin K-dependent coagulation factors. Chemically, it is 3-(and is a racemic mixture of the R- and S-enantiomers. Crystalline warfarin sodium is an i...
    Active IngredientWarfarin sodium
    Dosage FormTablet
    RouteOral
    Strength2.5mg; 7.5mg; 1mg; 5mg; 4mg; 6mg; 2mg; 10mg; 3mg
    Market StatusPrescription
    CompanyAmneal Pharms; Taro; Invagen Pharms; Ipca Labs; Zydus Pharms Usa; Pliva; Mylan; Barr

    3 of 4  
    Drug NameJantoven
    PubMed HealthWarfarin
    Drug ClassesAnticoagulant
    Drug LabelJantovenTablets (crystalline warfarin sodium) is an anticoagulant which acts by inhibiting vitamin K-dependent coagulation factors. Chemically, it is 3-(and is a racemic mixture of the R- and S-enantiomers. Crystalline warfarin sodium is an isopropan...
    Active IngredientWarfarin sodium
    Dosage FormTablet
    RouteOral
    Strength2.5mg; 7.5mg; 1mg; 5mg; 4mg; 6mg; 2mg; 10mg; 3mg
    Market StatusPrescription
    CompanyUsl Pharma

    4 of 4  
    Drug NameWarfarin sodium
    Drug LabelWarfarin sodium tablet (crystalline warfarin sodium) is an anticoagulant, which acts by inhibiting vitamin K-dependent coagulation factors. Chemically, it is 3-(and is a racemic mixture of the R- and S-enantiomers. Crystalline warfarin sodium is an i...
    Active IngredientWarfarin sodium
    Dosage FormTablet
    RouteOral
    Strength2.5mg; 7.5mg; 1mg; 5mg; 4mg; 6mg; 2mg; 10mg; 3mg
    Market StatusPrescription
    CompanyAmneal Pharms; Taro; Invagen Pharms; Ipca Labs; Zydus Pharms Usa; Pliva; Mylan; Barr

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Anticoagulants

    Agents that prevent BLOOD CLOTTING. (See all compounds classified as Anticoagulants.)

    Rodenticides

    Substances used to destroy or inhibit the action of rats, mice, or other rodents. (See all compounds classified as Rodenticides.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Vitamin K Inhibitors [MoA]; Vitamin K Antagonist [EPC]

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    09-Jan-2021
    18-Nov-2024
    KGS
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    Average Price (USD/KGS)

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    Quantity (KGS) & Unit rate (USD/KGS) over time

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    DOSAGE - TABLET;ORAL - 10MG

    USFDA APPLICATION NUMBER - 9218

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    DOSAGE - TABLET;ORAL - 1MG **Federal Register...DOSAGE - TABLET;ORAL - 1MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

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    DOSAGE - TABLET;ORAL - 7.5MG

    USFDA APPLICATION NUMBER - 9218

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    ABOUT THIS PAGE

    Waran Manufacturers

    A Waran manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Waran, including repackagers and relabelers. The FDA regulates Waran manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Waran API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Waran manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Waran Suppliers

    A Waran supplier is an individual or a company that provides Waran active pharmaceutical ingredient (API) or Waran finished formulations upon request. The Waran suppliers may include Waran API manufacturers, exporters, distributors and traders.

    click here to find a list of Waran suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Waran USDMF

    A Waran DMF (Drug Master File) is a document detailing the whole manufacturing process of Waran active pharmaceutical ingredient (API) in detail. Different forms of Waran DMFs exist exist since differing nations have different regulations, such as Waran USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Waran DMF submitted to regulatory agencies in the US is known as a USDMF. Waran USDMF includes data on Waran's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Waran USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Waran suppliers with USDMF on PharmaCompass.

    Waran CEP

    A Waran CEP of the European Pharmacopoeia monograph is often referred to as a Waran Certificate of Suitability (COS). The purpose of a Waran CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Waran EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Waran to their clients by showing that a Waran CEP has been issued for it. The manufacturer submits a Waran CEP (COS) as part of the market authorization procedure, and it takes on the role of a Waran CEP holder for the record. Additionally, the data presented in the Waran CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Waran DMF.

    A Waran CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Waran CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Waran suppliers with CEP (COS) on PharmaCompass.

    Waran WC

    A Waran written confirmation (Waran WC) is an official document issued by a regulatory agency to a Waran manufacturer, verifying that the manufacturing facility of a Waran active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Waran APIs or Waran finished pharmaceutical products to another nation, regulatory agencies frequently require a Waran WC (written confirmation) as part of the regulatory process.

    click here to find a list of Waran suppliers with Written Confirmation (WC) on PharmaCompass.

    Waran NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Waran as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Waran API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Waran as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Waran and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Waran NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Waran suppliers with NDC on PharmaCompass.

    Waran GMP

    Waran Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Waran GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Waran GMP manufacturer or Waran GMP API supplier for your needs.

    Waran CoA

    A Waran CoA (Certificate of Analysis) is a formal document that attests to Waran's compliance with Waran specifications and serves as a tool for batch-level quality control.

    Waran CoA mostly includes findings from lab analyses of a specific batch. For each Waran CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Waran may be tested according to a variety of international standards, such as European Pharmacopoeia (Waran EP), Waran JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Waran USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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