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1. 1-(2-(naphth-2-yl)ethyl)-4-(3-trifluoromethylphenyl)-1,2,5,6-tetrahydropyridine Hydrochloride
2. 1-(2-(naphth-2-yl)ethyl)-4-(trifluoromethylphenyl)-1,2,5,6-tetrahydropyridine Hydrochloride
3. Sr 57746a
4. Sr-57746a
5. Sr57746a
6. Xaliproden Hydrochloride
1. 135354-02-8
2. Sr 57746
3. Xaliproden (usan)
4. V8ql94knqo
5. Pyridine, 1,2,3,6-tetrahydro-1-(2-(2-naphthalenyl)ethyl)-4-(3-(trifluoromethyl)phenyl)-
6. Chebi:48520
7. 1,2,3,6-tetrahydro-1-(2-(2-naphthyl)ethyl)-4-(alpha,alpha,alpha-trifluoro-m-tolyl)pyridine
8. Sr-57746
9. Xaliproden [usan]
10. 1,2,3,6-tetrahydro-1-(2-(2-naphthalenyl)ethyl)-4-(3-(trifluoromethyl)phenyl)-pyridine
11. 1-(2-(2-naphthyl)ethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine
12. 1-[2-(2-naphthyl)ethyl]-4-[3-(trifluoromethyl)phenyl]-1,2,3,6-tetrahydropyridine
13. Ncgc00167574-01
14. Unii-v8ql94knqo
15. Xaliproden [usan:inn:ban]
16. 1-[2-(2-naphthyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine
17. Xaliproden [mi]
18. Xaliproden [inn]
19. 1-(2-naphthalen-2-ylethyl)-4-[3-(trifluoromethyl)phenyl]-3,6-dihydro-2h-pyridine
20. Xaliproden [who-dd]
21. Schembl137094
22. Chembl1512580
23. Dtxsid9048306
24. Bdbm82363
25. Zinc577115
26. Pdsp1_000054
27. Pdsp2_000054
28. Db06393
29. Sr 57746 A
30. Ncgc00167574-02
31. Cas_90494-79-4
32. Db-063077
33. Ft-0736660
34. D06327
35. L001401
36. Brd-k88358234-003-01-4
37. Q12745720
38. 1-(2-naphthalen-2-ylethyl)-4-[3-(trifluoromethyl)phenyl]-1,2,3,6-tetrahydropyridine
39. 1-[2(naphth-2-yl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,5,6-tetrahydropyridine
40. 1-[2-(naphth-2-yl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine
Molecular Weight | 381.4 g/mol |
---|---|
Molecular Formula | C24H22F3N |
XLogP3 | 6.2 |
Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 4 |
Rotatable Bond Count | 4 |
Exact Mass | 381.17043419 g/mol |
Monoisotopic Mass | 381.17043419 g/mol |
Topological Polar Surface Area | 3.2 Ų |
Heavy Atom Count | 28 |
Formal Charge | 0 |
Complexity | 541 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
Investigated for use/treatment in amyotrophic lateral sclerosis (ALS) and alzheimer's disease.
Serotonin 5-HT1 Receptor Agonists
Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT1 RECEPTORS. Included under this heading are agonists for one or more of the specific 5-HT1 receptor subtypes. (See all compounds classified as Serotonin 5-HT1 Receptor Agonists.)
N - Nervous system
N07 - Other nervous system drugs
N07X - Other nervous system drugs
N07XX - Other nervous system drugs
N07XX03 - Xaliproden
Xaliproden is an orally-active, synthetic, non-peptidic 5-hydroxytryptamine (5-HT) 1A receptor agonist with neurotrophic and neuroprotective activities. Although its mechanism of action is not fully understood, xaliproden appears to either mimic the effects of neurotrophins or stimulate their synthesis, thereby stimulating neuronal cell differentiation and proliferation and inhibiting neuronal cell death. The neuroprotective effect of this agent involves the activation of MAP kinase pathways via stimulation of the 5-HT1A receptor.
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PharmaCompass offers a list of Xaliproden API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Xaliproden manufacturer or Xaliproden supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Xaliproden manufacturer or Xaliproden supplier.
PharmaCompass also assists you with knowing the Xaliproden API Price utilized in the formulation of products. Xaliproden API Price is not always fixed or binding as the Xaliproden Price is obtained through a variety of data sources. The Xaliproden Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Xaliproden manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Xaliproden, including repackagers and relabelers. The FDA regulates Xaliproden manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Xaliproden API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Xaliproden supplier is an individual or a company that provides Xaliproden active pharmaceutical ingredient (API) or Xaliproden finished formulations upon request. The Xaliproden suppliers may include Xaliproden API manufacturers, exporters, distributors and traders.
Xaliproden Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Xaliproden GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Xaliproden GMP manufacturer or Xaliproden GMP API supplier for your needs.
A Xaliproden CoA (Certificate of Analysis) is a formal document that attests to Xaliproden's compliance with Xaliproden specifications and serves as a tool for batch-level quality control.
Xaliproden CoA mostly includes findings from lab analyses of a specific batch. For each Xaliproden CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Xaliproden may be tested according to a variety of international standards, such as European Pharmacopoeia (Xaliproden EP), Xaliproden JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Xaliproden USP).