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Synopsis

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Chemistry

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Also known as: Xanthinol nicotinate, 437-74-1, Xantinol nicotinate, Complamin, Angioamin, Teonicol
Molecular Formula
C19H26N6O6
Molecular Weight
434.4  g/mol
InChI Key
GEPMAHVDJHFBJI-UHFFFAOYSA-N
FDA UNII
8G60H12X2D

Xanthinol Nicotinate
A vasodilator used in peripheral vascular disorders and insufficiency. It may cause gastric discomfort and hypotension.
1 2D Structure

Xanthinol Nicotinate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-[2-hydroxy-3-[2-hydroxyethyl(methyl)amino]propyl]-1,3-dimethylpurine-2,6-dione;pyridine-3-carboxylic acid
2.1.2 InChI
InChI=1S/C13H21N5O4.C6H5NO2/c1-15(4-5-19)6-9(20)7-18-8-14-11-10(18)12(21)17(3)13(22)16(11)2;8-6(9)5-2-1-3-7-4-5/h8-9,19-20H,4-7H2,1-3H3;1-4H,(H,8,9)
2.1.3 InChI Key
GEPMAHVDJHFBJI-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(CN(C)CCO)O.C1=CC(=CN=C1)C(=O)O
2.2 Other Identifiers
2.2.1 UNII
8G60H12X2D
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Complamin

2. Complamine

3. Komplamin

4. Niacinate, Xanthinol

5. Nicotinate, Xanthinol

6. Nicotinate, Xantinol

7. Sadamin

8. Sadamine

9. Teonicol

10. Xanthinol Nicotinate

11. Xantinol Nicotinate

12. Xantinol-nicotinat-ratiopharm

13. Xavin

2.3.2 Depositor-Supplied Synonyms

1. Xanthinol Nicotinate

2. 437-74-1

3. Xantinol Nicotinate

4. Complamin

5. Angioamin

6. Teonicol

7. Complamex

8. Landrina

9. Sadamine

10. Stenalgil

11. Xanidil

12. Vedrin

13. Complamin Retard

14. Xavin

15. Xanthinol Niacinate [usan]

16. Sk 331 A

17. Xantinol Nicotinate [inn]

18. Nsc-113217

19. Xanthinol Niacinate (usan)

20. Mls000028609

21. Sk 331a

22. 8g60h12x2d

23. Nsc113217

24. Nicotinic Acid, Compd. With 3,7-dihydro-7-(2-hydroxy-3-((2-hydroxyethyl) Methylamino)propyl)-1,3-dimethyl-1h-purine-2,6-dione

25. Ncgc00021151-02

26. Angiomin

27. Sadamin

28. Smr000058741

29. 3-pyridinecarboxylic Acid Compd. With 3,7-dihydro-7-(2-hydroxy-3-((2-hydroxyethyl)methylamino)propyl)-1,3-dimethyl-1h-purine-2,6-dione (1:1)

30. 7-(2-hydroxy-3-((2-hydroxyethyl)(methyl)amino)propyl)-1,3-dimethyl-1h-purine-2,6(3h,7h)-dione Nicotinate

31. 7-[2-hydroxy-3-[2-hydroxyethyl(methyl)amino]propyl]-1,3-dimethylpurine-2,6-dione;pyridine-3-carboxylic Acid

32. Xanthinolium Nicotinicum

33. Xantinoli Nicotinas

34. Xantinolo Nicotinato [dcit]

35. 7-{2-hydroxy-3-((2-hydroxyethyl)methylamino)propyl}theophylline, Compound With Nicotinic Acid (1:1)

36. Nicotinic Acid, Compd. With 7-[2-hydroxy-3-[(2-hydroxyethyl)methylamino]propyl]theophylline (1:1)

37. Xantinolo Nicotinato

38. Nicotinate De Xantinol

39. Nicotinato De Xantinol

40. Xantinoli Nicotinas [inn-latin]

41. Einecs 207-115-7

42. Nicotinate De Xantinol [inn-french]

43. Nicotinato De Xantinol [inn-spanish]

44. Methoxylin, Compd. With Nicotinic Acid

45. Nsc 113217

46. Unii-8g60h12x2d

47. Angioamincomplamin

48. Complamin (tn)

49. 7-(2-hydroxy-3-((2-hydroxyethyl)methylamino)propyl)theophylline, Compound With Nicotinic Acid (1:1)

50. 7-[2-hydroxy-3-[(2-hydroxyethyl)methylamino]propyl]theophylline, Compound With Nicotinic Acid (1:1)

51. Opera_id_260

52. 7-(3-(n-(2-hydroxyethyl)amino)-2-hydroxypropyl)thiophylline Nicotinate

53. Dsstox_cid_3743

54. Xantinol Nicotinate ,(s)

55. 7-(2-hydroxy-3-((2-hydroxyethyl)methylamino)propyl)theophylline Compd. With Nicotinic Acid

56. Dsstox_rid_77178

57. Dsstox_gsid_23743

58. 7- 2-hydroxy-3-((2-hydroxyethyl)methylamino)propyl Theophylline, Compound With Nicotinic Acid (1:1)

59. Mls001148608

60. Mls001424204

61. Mls006010909

62. Schembl121655

63. Chembl1560089

64. Dtxsid0023743

65. Xanthinol Niacinate [mi]

66. Hms2052e09

67. Hms2230j12

68. Hms3371o12

69. Hms3394e09

70. Hy-b1815

71. Xantinol Nicotinate [mart.]

72. Tox21_110866

73. Mfcd00058342

74. S4868

75. Xantinol Nicotinate [who-dd]

76. Akos005267237

77. Ccg-101097

78. Ccg-269063

79. Nc00347

80. Ncgc00164435-01

81. 7-[2-hydroxy-3-[2-hydroxyethyl(methyl)amino]propyl]-1,3-dimethyl-purine-2,6-dione; Nicotinic Acid

82. As-11613

83. Cas-437-74-1

84. Nicotinic Acid, Compd. With 7-(2-hydroxy-3-((2-hydroxyethyl)methylamino)propyl)theophylline(1:1)

85. Db-051164

86. Cs-0013860

87. Ft-0603393

88. D06334

89. E75972

90. A913692

91. Sr-01000000242

92. Q5814478

93. Sr-01000000242-4

94. 3-pyridinecarboxylic Acid Compd. With 3,3-dimethyl-1h-purine-2,6-dione (1:1)

95. (+/-)-7-(2-hydroxy-3-((2-hydroxyethyl)methylamino)propyl)theophylline, Compound With Nicotinic Acid (1:1)

96. {7-[2-hydroxy-3-[(2-hydroxyethyl)methylamino]propyl]theophylline,} Compound With Nicotinic Acid (1:1)

97. 3-pyridinecarboxylic Acid & {3,7-dihydro-7-[2-hydroxy-3-[(2-hydroxyethyl)methylamino]propyl]-1,} 3-dimethyl-1h-purine-2,6-dione (1:1)

98. 3-pyridinecarboxylic Acid, Compd. With 3, {7-dihydro-7-[2-hydroxy-3-[(2-hydroxyethyl)methylamino]propyl]-1,} 3-dimethyl-1h-purine-2,6-dione (1:1)

99. 3-pyridinecarboxylic Acid,7-dihydro-7-[2-hydroxy-3-[(2-hydroxyethyl)methylamino]propyl]-1,3-dimethyl-1h-purine-2,6-dione (1:1)

100. 7-{2-hydroxy-3-[(2-hydroxyethyl)(methyl)amino]propyl}-1,3-dimethyl-2,3,6,7-tetrahydro-1h-purine-2,6-dione; Pyridine-3-carboxylic Acid

101. Nicotinic Acid Compound With 7-(2-hydroxy-3-((2-hydroxyethyl)(methyl)amino)propyl)-1,3-dimethyl-3,7-dihydro-1h-purine-2,6-dione (1:1)

102. Nicotinic Acid, Compd. With {7-[2-hydroxy-3-[(2-hydroxyethyl)methylamino]propyl]theophylline} (1:1)

103. Pyridine-3-carboxylic Acid - 7-{2-hydroxy-3-[(2-hydroxyethyl)(methyl)amino]propyl}-1,3-dimethyl-3,7-dihydro-1h-purine-2,6-dione (1:1)

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 434.4 g/mol
Molecular Formula C19H26N6O6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count7
Exact Mass434.19138257 g/mol
Monoisotopic Mass434.19138257 g/mol
Topological Polar Surface Area152 Ų
Heavy Atom Count31
Formal Charge0
Complexity548
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Vasodilator Agents

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)


4.2 ATC Code

C - Cardiovascular system

C04 - Peripheral vasodilators

C04A - Peripheral vasodilators

C04AD - Purine derivatives

C04AD02 - Xantinol nicotinate


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Xanthinol Nicotinate Manufacturers

A Xanthinol Nicotinate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Xanthinol Nicotinate, including repackagers and relabelers. The FDA regulates Xanthinol Nicotinate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Xanthinol Nicotinate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Xanthinol Nicotinate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Xanthinol Nicotinate Suppliers

A Xanthinol Nicotinate supplier is an individual or a company that provides Xanthinol Nicotinate active pharmaceutical ingredient (API) or Xanthinol Nicotinate finished formulations upon request. The Xanthinol Nicotinate suppliers may include Xanthinol Nicotinate API manufacturers, exporters, distributors and traders.

click here to find a list of Xanthinol Nicotinate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Xanthinol Nicotinate GMP

Xanthinol Nicotinate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Xanthinol Nicotinate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Xanthinol Nicotinate GMP manufacturer or Xanthinol Nicotinate GMP API supplier for your needs.

Xanthinol Nicotinate CoA

A Xanthinol Nicotinate CoA (Certificate of Analysis) is a formal document that attests to Xanthinol Nicotinate's compliance with Xanthinol Nicotinate specifications and serves as a tool for batch-level quality control.

Xanthinol Nicotinate CoA mostly includes findings from lab analyses of a specific batch. For each Xanthinol Nicotinate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Xanthinol Nicotinate may be tested according to a variety of international standards, such as European Pharmacopoeia (Xanthinol Nicotinate EP), Xanthinol Nicotinate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Xanthinol Nicotinate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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