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    Also known as: 65-19-0, Yohimbine hcl, Antagonil, Yohimbe, Aphrodine hydrochloride, Yohimbine monohydrochloride
    Molecular Formula
    C21H27ClN2O3
    Molecular Weight
    390.9  g/mol
    InChI Key
    PIPZGJSEDRMUAW-VJDCAHTMSA-N
    FDA UNII
    NB2E1YP49F
    Yohimbine Hydrochloride
    A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION.
    1 2D Structure

    Yohimbine Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    methyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride
    2.1.2 InChI
    InChI=1S/C21H26N2O3.ClH/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24;/h2-5,12,15,17-19,22,24H,6-11H2,1H3;1H/t12-,15-,17-,18-,19+;/m0./s1
    2.1.3 InChI Key
    PIPZGJSEDRMUAW-VJDCAHTMSA-N
    2.1.4 Canonical SMILES
    COC(=O)C1C(CCC2C1CC3C4=C(CCN3C2)C5=CC=CC=C5N4)O.Cl
    2.1.5 Isomeric SMILES
    COC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    NB2E1YP49F
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Aphrodine Hydrochloride

    2. Aphrodyne

    3. Corynanthine

    4. Corynanthine Tartrate

    5. Hydrochloride, Aphrodine

    6. Hydrochloride, Yohimbine

    7. Pluriviron

    8. Rauhimbine

    9. Rauwolscine

    10. Tartrate, Corynanthine

    11. Yocon

    12. Yohimbin Spiegel

    13. Yohimbine

    14. Yohimbine Houd

    15. Yohimex

    2.3.2 Depositor-Supplied Synonyms

    1. 65-19-0

    2. Yohimbine Hcl

    3. Antagonil

    4. Yohimbe

    5. Aphrodine Hydrochloride

    6. Yohimbine Monohydrochloride

    7. Yohimbine (hydrochloride)

    8. Nb2e1yp49f

    9. Actibine

    10. Mfcd00012674

    11. 17-hydroxyyohimban-16-carboxylic Acid Methyl Ester Hydrochloride

    12. Yohimbine Chloride

    13. Nsc-19509

    14. Yohimbin Hcl

    15. Chembl537669

    16. Methyl (1s,15r,18s,19r,20s)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride

    17. Methyl (1s,15r,18s,19r,20s)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate Hydrochloride

    18. Smr000058527

    19. Yohimbin Hydrochloride [usp]

    20. Yohimbin Hydrochloride

    21. Sr-01000597896

    22. Einecs 200-600-4

    23. Nsc 19509

    24. Unii-nb2e1yp49f

    25. Parkimbine

    26. Aphrodyne

    27. Gynimbine

    28. Menolysin

    29. Thybine

    30. Tosanpin

    31. Yobinol

    32. Yohydrol

    33. Yocon

    34. Ai3-60247

    35. Dayto-himbin

    36. Sr-01000075297

    37. Yohimbine, Hcl

    38. Yohimbine Hydrochloride [usp:ban]

    39. Prestwick_961

    40. Nsc19509

    41. Yohimbine-hydrochloride

    42. Yohimban-16-carboxylic Acid, 17-hydroxy-, Methyl Ester, Monohydrochloride, (16alpha,17alpha)-

    43. Mls001306411

    44. Mls001333983

    45. Yohimbine Hydrochloride (usp)

    46. Dtxsid40891272

    47. Hms1569f10

    48. Yohimbine Hydrochloride (antagonil)

    49. (1r,2s,4ar,13bs,14as)-methyl 2-hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate Hydrochloride

    50. Bcp19708

    51. Hy-n0127

    52. Nih 9689

    53. Tox21_501210

    54. Yohimbine Hydrochloride [mi]

    55. S2373

    56. Akos015951349

    57. Ccg-208327

    58. Cs-5238

    59. Lp01210

    60. Yohimbine Hydrochloride [mart.]

    61. Yohimbine Hydrochloride [vandf]

    62. 17alpha-hydroxy-20-alpha-yohimban-16-beta-carboxylic Acid, Methyl Ester, Hydrochloride

    63. Yohimban-16-alpha-carboxylic Acid, 17-alpha-hydroxy-, Methyl Ester, Hydrochloride

    64. Yohimban-16alpha-carboxylic Acid, 17alpha-hydroxy-, Methyl Ester, Monohydrochloride

    65. Yohimbine Hydrochloride [usp-rs]

    66. Yohimbine Hydrochloride [who-dd]

    67. Ncgc00094457-01

    68. Ncgc00261895-01

    69. Ac-22571

    70. As-13939

    71. Yohimbine Hydrochloride [green Book]

    72. Yohimbine Hydrochloride, Analytical Standard

    73. Eu-0101210

    74. N1704

    75. Sw199050-2

    76. Y0002

    77. Yohimbine Hydrochloride [ep Monograph]

    78. D06671

    79. Y 3125

    80. Yohimbine Hydrochloride [usp Monograph]

    81. Yohimbine Hydrochloride, >=98% (tlc), Powder

    82. 012y674

    83. Q-201938

    84. Sr-01000075297-1

    85. Sr-01000597896-1

    86. Sr-01000597896-4

    87. Q15680050

    88. 17?-hydroxyyohimban-16?-carboxylic Acid Methyl Ester Hydrochloride

    89. Yohimbine Hydrochloride, European Pharmacopoeia (ep) Reference Standard

    90. Yohimbine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    91. 17.alpha.-hydroxy-20-.alpha.-yohimban-16-.beta.-carboxylic Acid, Methyl Ester, Hydrochloride

    92. Yohimban-16-carboxylic Acid, 17-hydroxy-, Methyl Ester, Hydrochloride (1:1), (16alpha,17alpha)-

    2.4 Create Date
    2005-07-19
    3 Chemical and Physical Properties
    Molecular Weight 390.9 g/mol
    Molecular Formula C21H27ClN2O3
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count2
    Exact Mass390.1710204 g/mol
    Monoisotopic Mass390.1710204 g/mol
    Topological Polar Surface Area65.6 Ų
    Heavy Atom Count27
    Formal Charge0
    Complexity555
    Isotope Atom Count0
    Defined Atom Stereocenter Count5
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Urological Agents

    Drugs used in the treatment of urological conditions and diseases such as URINARY INCONTINENCE and URINARY TRACT INFECTIONS. (See all compounds classified as Urological Agents.)

    Adrenergic alpha-2 Receptor Antagonists

    Drugs that bind to and block the activation of ADRENERGIC ALPHA-2 RECEPTORS. (See all compounds classified as Adrenergic alpha-2 Receptor Antagonists.)

    Mydriatics

    Agents that dilate the pupil. They may be either sympathomimetics or parasympatholytics. (See all compounds classified as Mydriatics.)

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LTD","supplierCountry":"INDIA","foreign_port":"SYDNEY","customer":"TO THE ORDER OF","customerCountry":"AUSTRALIA","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"1600","totalValueFC":"4629.4","currency":"USD","unitRateINR":128993,"date":"03-Jul-2024","totalValueINR":"386979","totalValueInUsd":"4629.4","indian_port":"Bombay Air","hs_no":"29391900","bill_no":"2159768","productDescription":"API","marketType":"REGULATED MARKET","country":"AUSTRALIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"VENKATESH,MAHANT ROAD EXTN,, VILE PARLE[E],MUMBAI, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720722600,"product":"YOHIMBINE HYDROCHLORIDE (HCL)","address":"12\/12, SHAKTI NAGAR,","city":"DELHI","supplier":"WAHSUN PHARMACEUTICAL CO., LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"COOPER LAB","customerCountry":"INDIA","quantity":"1.53","actualQuantity":"1.53","unit":"KGS","unitRateFc":"1666.7","totalValueFC":"2576.3","currency":"USD","unitRateINR":"140752.8","date":"12-Jul-2024","totalValueINR":"215351.72","totalValueInUsd":"2576.3","indian_port":"Delhi Air","hs_no":"29371900","bill_no":"4461842","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"2 ND FLOOR, NO. 1830, HUQING ROAD,QINGPU DISTRICT, SHANGHAISDNF CN","customerAddress":"12\/12, SHAKTI NAGAR,"}]
    22-Jun-2021
    12-Jul-2024
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    ABOUT THIS PAGE

    Yohimbine Hydrochloride Manufacturers

    A Yohimbine Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Yohimbine Hydrochloride, including repackagers and relabelers. The FDA regulates Yohimbine Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Yohimbine Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Yohimbine Hydrochloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Yohimbine Hydrochloride Suppliers

    A Yohimbine Hydrochloride supplier is an individual or a company that provides Yohimbine Hydrochloride active pharmaceutical ingredient (API) or Yohimbine Hydrochloride finished formulations upon request. The Yohimbine Hydrochloride suppliers may include Yohimbine Hydrochloride API manufacturers, exporters, distributors and traders.

    click here to find a list of Yohimbine Hydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Yohimbine Hydrochloride USDMF

    A Yohimbine Hydrochloride DMF (Drug Master File) is a document detailing the whole manufacturing process of Yohimbine Hydrochloride active pharmaceutical ingredient (API) in detail. Different forms of Yohimbine Hydrochloride DMFs exist exist since differing nations have different regulations, such as Yohimbine Hydrochloride USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Yohimbine Hydrochloride DMF submitted to regulatory agencies in the US is known as a USDMF. Yohimbine Hydrochloride USDMF includes data on Yohimbine Hydrochloride's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Yohimbine Hydrochloride USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Yohimbine Hydrochloride suppliers with USDMF on PharmaCompass.

    Yohimbine Hydrochloride WC

    A Yohimbine Hydrochloride written confirmation (Yohimbine Hydrochloride WC) is an official document issued by a regulatory agency to a Yohimbine Hydrochloride manufacturer, verifying that the manufacturing facility of a Yohimbine Hydrochloride active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Yohimbine Hydrochloride APIs or Yohimbine Hydrochloride finished pharmaceutical products to another nation, regulatory agencies frequently require a Yohimbine Hydrochloride WC (written confirmation) as part of the regulatory process.

    click here to find a list of Yohimbine Hydrochloride suppliers with Written Confirmation (WC) on PharmaCompass.

    Yohimbine Hydrochloride GMP

    Yohimbine Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Yohimbine Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Yohimbine Hydrochloride GMP manufacturer or Yohimbine Hydrochloride GMP API supplier for your needs.

    Yohimbine Hydrochloride CoA

    A Yohimbine Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Yohimbine Hydrochloride's compliance with Yohimbine Hydrochloride specifications and serves as a tool for batch-level quality control.

    Yohimbine Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Yohimbine Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Yohimbine Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Yohimbine Hydrochloride EP), Yohimbine Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Yohimbine Hydrochloride USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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