Find Ypo0Ntk49O manufacturers, exporters & distributors on PharmaCompass

Ypo0Ntk49O

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 USDMF

1 API Suppliers
1 USDMF

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 72471-80-8, Ypo0ntk49o, Acetic acid;(3s,4r)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine, Unii-ypo0ntk49o, Schembl4200728, Dtxsid70222772

Molecular Formula

C₂₁H₂₄FNO₅

Molecular Weight

389.4 g/mol

InChI Key

RQBJOWKBGCDPOS-RVXRQPKJSA-N

FDA UNII

YPO0NTK49O

A serotonin uptake inhibitor that is effective in the treatment of depression.

1 2D Structure

Ypo0Ntk49O

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

acetic acid;(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine

2.1.2 InChI

InChI=1S/C19H20FNO3.C2H4O2/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;1-2(3)4/h1-6,9,14,17,21H,7-8,10-12H2;1H3,(H,3,4)/t14-,17-;/m0./s1

2.1.3 InChI Key

RQBJOWKBGCDPOS-RVXRQPKJSA-N

2.1.4 Canonical SMILES

CC(=O)O.C1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4

2.1.5 Isomeric SMILES

CC(=O)O.C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4

2.2 Other Identifiers

2.2.1 UNII

YPO0NTK49O

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Aropax

2. Brl 29060

3. Brl-29060

4. Brl29060

5. Fg 7051

6. Fg-7051

7. Fg7051

8. Paroxetine

9. Paroxetine Hydrochloride

10. Paroxetine Hydrochloride Anhydrous

11. Paroxetine Hydrochloride Hemihydrate

12. Paroxetine Hydrochloride, Hemihydrate

13. Paroxetine Maleate

14. Paroxetine, Cis-(+)-isomer

15. Paroxetine, Cis-(-)-isomer

16. Paroxetine, Trans-(+)-isomer

17. Paxil

18. Seroxat

2.3.2 Depositor-Supplied Synonyms

1. 72471-80-8

2. Ypo0ntk49o

3. Acetic Acid;(3s,4r)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine

4. Unii-ypo0ntk49o

5. Schembl4200728

6. Dtxsid70222772

7. Paroxetine Acetate [who-dd]

8. Q27294647

9. Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-, (3s-trans)-, Acetate

10. Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-, Acetate (1:1), (3s,4r)-

2.4 Create Date

2006-10-25

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₂₄FNO₅
Molecular Weight	389.4 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	4
Exact Mass	389.16385103 g/mol
Monoisotopic Mass	389.16385103 g/mol
Topological Polar Surface Area	77 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	433
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Antidepressive Agents, Second-Generation

A structurally and mechanistically diverse group of drugs that are not tricyclics or monoamine oxidase inhibitors. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake. (See all compounds classified as Antidepressive Agents, Second-Generation.)

Cytochrome P-450 CYP2D6 Inhibitors

Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP2D6. (See all compounds classified as Cytochrome P-450 CYP2D6 Inhibitors.)

Selective Serotonin Reuptake Inhibitors

Compounds that specifically inhibit the reuptake of serotonin in the brain. (See all compounds classified as Selective Serotonin Reuptake Inhibitors.)

API SUPPLIERS