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Chemistry

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Also known as: Oxozinc, Zinc white, Zinc oxide powder, Amalox, Chinese white, Snow white
Molecular Formula
OZn
Molecular Weight
81.4  g/mol
InChI Key
XLOMVQKBTHCTTD-UHFFFAOYSA-N

Zinc Oxide
A mild astringent and topical protectant with some antiseptic action. It is also used in bandages, pastes, ointments, dental cements, and as a sunblock.
1 2D Structure

Zinc Oxide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
oxozinc
2.1.2 InChI
InChI=1S/O.Zn
2.1.3 InChI Key
XLOMVQKBTHCTTD-UHFFFAOYSA-N
2.1.4 Canonical SMILES
O=[Zn]
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Nogenol

2. Lassar Paste

3. Lassar's Paste

4. Lassars Paste

5. Oxide, Zinc

6. Paste, Lassar's

2.2.2 Depositor-Supplied Synonyms

1. Oxozinc

2. Zinc White

3. Zinc Oxide Powder

4. Amalox

5. Chinese White

6. Snow White

7. Emanay Zinc Oxide

8. Felling Zinc Oxide

9. Akro-zinc Bar 85

10. Flowers Of Zinc

11. Mfcd00011300

12. Azo-33

13. Outmine

14. Supertah

15. Zincite

16. Zincoid

17. Azodox

18. Ozide

19. Ozlo

20. Zinc Monoxide

21. Lassars Paste

22. Flores De Zinci

23. Lassar Paste

24. Zinci Oxicum

25. Hubbuck's White

26. Blanc De Zinc

27. Unichem Zo

28. Vandem Vac

29. Vandem Voc

30. Vandem Vpc

31. Green Seal-8

32. Philosopher's Wool

33. White Seal-7

34. K-zinc

35. Zno

36. Powder Base 900

37. Protox Type 166

38. Protox Type 167

39. Protox Type 168

40. Protox Type 169

41. Protox Type 267

42. Protox Type 268

43. Akro-zinc Bar 90

44. Azodox-55

45. Azodox-55tt

46. Red Seal 9

47. Emar

48. Ci Pigment White 4

49. Electrox 2500

50. Actox 14

51. Actox 16

52. Kadox 15

53. Kadox 72

54. Kadox-25

55. Zinc Oxide [usan]

56. Zinca 20

57. Protox 166

58. Protox 168

59. Protox 169

60. Caswell No. 920

61. Electox 2500

62. Cadox Xx 78

63. Actox 216

64. Cynku Tlenek [polish]

65. Desitin

66. Nogenol

67. C-weiss 8 [german]

68. Zincum Oxidatum

69. Azo-55tt

70. Azo-66tt

71. Azo-77tt

72. Cynku Tlenek

73. Zinc Gelatin

74. Oxyde De Zinc

75. Zinc Oxide Fume

76. Rvpaque

77. Azo 22

78. Azo-55

79. Azo-66

80. Azo-77

81. No-genol

82. Zinc Oxide Substrate, 10x10x0.5mm, Polished One Side, 0001 Orientation

83. Zinc Oxide Substrate, 10x10x0.5mm, Polished Two Sides, 0001 Orientation

84. Pigment White 4

85. Zinc Oxide, 99.99% Trace Metals Basis

86. 174846-84-5

87. Giap 10

88. Ccris 1309

89. C-weiss 8

90. Zn 0701t

91. Hsdb 5024

92. A&d Medicated Ointment

93. Xx 78

94. Einecs 215-222-5

95. Unii-soi2loh54z

96. Zinc Oxide [usp:jan]

97. Xx 203

98. Xx 601

99. Epa Pesticide Chemical Code 088502

100. Zinkoxid

101. Ai3-00277

102. Oxido De Cinc

103. Leaded Zinc Oxide

104. Zn-0401 E 3/16''

105. Zno Quantum Dots

106. Zinc Oxide Slurry

107. Zinc Oxide, Heavy

108. Zinc Oxide (tn)

109. Zinc Oxide Nanowire

110. Zinc Oxide Nanowires

111. Zine Oxide ,(s)

112. Zinc Oxide Dispersion

113. Zinc Oxide Nanopowder

114. Zinc Oxide, Nanotek?

115. Zinc Oxide Nanoparticle

116. Zinc Oxide, Puratronic

117. Zinc Oxide Quantum Dots

118. Zinc Oxide,99.99%

119. Ec 215-222-5

120. Zinc Oxide (jp17/usp)

121. Zinc Oxide, Sintered Tablets

122. Zinc Oxide, Lr, >=99%

123. Aluminium Doped Zno Dispersion

124. Zinc Oxide [usan:usp:jan]

125. Zinc Oxide, Analytical Standard

126. Zinc Oxide Nanopowder Dispersion

127. Chebi:36560

128. Zinc Oxide Nanopowder (type I)

129. Zinc Oxide, Nanoarc Zn-0605

130. Zinc Oxide, P.a., 99.0%

131. Zinc Oxide Nanopowder (type Ii)

132. Zinc Oxide Dispersion Wood Coating

133. Zinc Oxide Powder, 99.9% Nano

134. Yttrium Doped Zinc Oxide Dispersion

135. Europium Doped Zinc Oxide Dispersion

136. Zinc Oxide, Usp, 99-100.5%

137. Akos015904168

138. Zinc Oxide Nanoparticles / Nanopowder

139. Db09321

140. Zinc Oxide, Acs Reagent, >=99.0%

141. Zinc Oxide, 99.999% (metals Basis)

142. Zinc Oxide, 30nm,20 Wt.% Isopropanol

143. Zinc Oxide, Tested According To Ph.eur.

144. 8051-03-4

145. Zinc Oxide, 99.999% Trace Metals Basis

146. Zinc Oxide, Saj First Grade, >=99.0%

147. Zinc Oxide, Jis Special Grade, >=99.0%

148. Cs-0179846

149. Ft-0631786

150. Ft-0640838

151. Ft-0645092

152. Antimony Tin Dioxide (ato) Sputtering Targets

153. D01170

154. Zinc Oxide, Nanopowder, <100 Nm Particle Size

155. Q190077

156. Zinc Oxide Nanodispersion Type A-nonionic (70nm)

157. Zinc Oxide Nanodispersion Type B-anionic (70nm)

158. Zinc Oxide Nanodispersion Type C-cationic (70nm)

159. Zinc Oxide, Nanowires, Diam. X L 90 Nm X 1 Mum

160. J-005999

161. Zinc Oxide, Nanowires, Diam. X L 50 Nm X 300 Nm

162. Zinc Oxide, Nanowires, Diam. X L 300 Nm X 4-5 Mum

163. Zinc Oxide, Puriss. P.a., Acs Reagent, >=99.0% (kt)

164. Azo Powder / Azo Micropowder / Zno Doped With Metal Aluminum

165. Zinc Oxide, Nanopowder, <50 Nm Particle Size (bet), >97%

166. Zinc Oxide, Reagentplus(r), Powder, <5 Mum Particle Size, 99.9%

167. Zinc Oxide, United States Pharmacopeia (usp) Reference Standard

168. 20 Wt% Zinc Oxide In Water, 20 Wt% (zno) (pale Yellow Powder), >99% Nano

169. Zinc Oxide Sputtering Target, 50.8mm (2.0in) Dia X 3.18mm (0.125in) Thick

170. Zinc Oxide Sputtering Target, 50.8mm (2.0in) Dia X 6.35mm (0.250in) Thick

171. Zinc Oxide Sputtering Target, 76.2mm (3.0in) Dia X 6.35mm (0.250in) Thick

172. Zinc Oxide, Dispersion, Nanoparticles, <110 Nm Particle Size, 40 Wt. % In Butyl Acetate

173. Zinc Oxide, Dispersion, Nanoparticles, 40 Wt. % In Ethanol, <130 Nm Particle Size

174. Zinc Oxide, Dispersion, Nanoparticles, <100 Nm Particle Size (tem), <=40 Nm Avg. Part. Size (aps), 20 Wt. % In H2o

175. Zinc Oxide, Nanotek Z1102pma, 50% In 1,2-propanediol Monomethyl Ether Acetate, Colloidal Dispersion

176. Zinc Oxide, Puriss., Meets Analytical Specification Of Ph. Eur., Bp, Usp, 99-100.5% (calc. For Dried Substance)

177. Zinc Oxide, Sputtering Target, Diam. X Thickness 3.00 In. X 0.125 In., 99.99% Trace Metals Basis

2.3 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 81.4 g/mol
Molecular Formula OZn
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass79.924056 g/mol
Monoisotopic Mass79.924056 g/mol
Topological Polar Surface Area17.1 Ų
Heavy Atom Count2
Formal Charge0
Complexity2
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

For adjunctive treatment of diaper dermatitis. Also, it can be used to treat minor skin irritations (eg, cuts, burns, and scrapes, poison ivy). Zinc oxide can be used in ointments, creams, and lotions to protect against sunburn and other damage to the skin caused by ultraviolet light.


FDA Label


5 Pharmacology and Biochemistry
5.1 Pharmacology

Zinc oxide has astringent, soothing and protective properties and is used in topical preparations for eczema, slight excoriations, wounds and haemorrhoids. It also reflects ultraviolet radiation and can be used as a physical sunscreen.


5.2 MeSH Pharmacological Classification

Dermatologic Agents

Drugs used to treat or prevent skin disorders or for the routine care of skin. (See all compounds classified as Dermatologic Agents.)


Sunscreening Agents

Chemical or physical agents that protect the skin from sunburn and erythema by absorbing or blocking ultraviolet radiation. (See all compounds classified as Sunscreening Agents.)


5.3 Absorption, Distribution and Excretion

Absorption

No significant percutaneous absorption from topically applied zinc oxide.


Route of Elimination

Intended for local use only, no systemic absorption.


Volume of Distribution

Intended for local use only, no systemic absorption.


Clearance

Intended for local use only, no systemic absorption.


5.4 Metabolism/Metabolites

Intended for local use only, no systemic absorption.


5.5 Biological Half-Life

Intended for local use only, no systemic absorption.


5.6 Mechanism of Action

It acts by providing a physical barrier to prevent skin irritation and help heal damaged skin.


API Reference Price

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08-Jan-2021
18-Dec-2024
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ABOUT THIS PAGE

Zinc Oxide Manufacturers

A Zinc Oxide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Zinc Oxide, including repackagers and relabelers. The FDA regulates Zinc Oxide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Zinc Oxide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Zinc Oxide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Zinc Oxide Suppliers

A Zinc Oxide supplier is an individual or a company that provides Zinc Oxide active pharmaceutical ingredient (API) or Zinc Oxide finished formulations upon request. The Zinc Oxide suppliers may include Zinc Oxide API manufacturers, exporters, distributors and traders.

click here to find a list of Zinc Oxide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Zinc Oxide USDMF

A Zinc Oxide DMF (Drug Master File) is a document detailing the whole manufacturing process of Zinc Oxide active pharmaceutical ingredient (API) in detail. Different forms of Zinc Oxide DMFs exist exist since differing nations have different regulations, such as Zinc Oxide USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Zinc Oxide DMF submitted to regulatory agencies in the US is known as a USDMF. Zinc Oxide USDMF includes data on Zinc Oxide's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Zinc Oxide USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Zinc Oxide suppliers with USDMF on PharmaCompass.

Zinc Oxide JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Zinc Oxide Drug Master File in Japan (Zinc Oxide JDMF) empowers Zinc Oxide API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Zinc Oxide JDMF during the approval evaluation for pharmaceutical products. At the time of Zinc Oxide JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Zinc Oxide suppliers with JDMF on PharmaCompass.

Zinc Oxide CEP

A Zinc Oxide CEP of the European Pharmacopoeia monograph is often referred to as a Zinc Oxide Certificate of Suitability (COS). The purpose of a Zinc Oxide CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Zinc Oxide EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Zinc Oxide to their clients by showing that a Zinc Oxide CEP has been issued for it. The manufacturer submits a Zinc Oxide CEP (COS) as part of the market authorization procedure, and it takes on the role of a Zinc Oxide CEP holder for the record. Additionally, the data presented in the Zinc Oxide CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Zinc Oxide DMF.

A Zinc Oxide CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Zinc Oxide CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Zinc Oxide suppliers with CEP (COS) on PharmaCompass.

Zinc Oxide WC

A Zinc Oxide written confirmation (Zinc Oxide WC) is an official document issued by a regulatory agency to a Zinc Oxide manufacturer, verifying that the manufacturing facility of a Zinc Oxide active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Zinc Oxide APIs or Zinc Oxide finished pharmaceutical products to another nation, regulatory agencies frequently require a Zinc Oxide WC (written confirmation) as part of the regulatory process.

click here to find a list of Zinc Oxide suppliers with Written Confirmation (WC) on PharmaCompass.

Zinc Oxide NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Zinc Oxide as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Zinc Oxide API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Zinc Oxide as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Zinc Oxide and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Zinc Oxide NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Zinc Oxide suppliers with NDC on PharmaCompass.

Zinc Oxide GMP

Zinc Oxide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Zinc Oxide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Zinc Oxide GMP manufacturer or Zinc Oxide GMP API supplier for your needs.

Zinc Oxide CoA

A Zinc Oxide CoA (Certificate of Analysis) is a formal document that attests to Zinc Oxide's compliance with Zinc Oxide specifications and serves as a tool for batch-level quality control.

Zinc Oxide CoA mostly includes findings from lab analyses of a specific batch. For each Zinc Oxide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Zinc Oxide may be tested according to a variety of international standards, such as European Pharmacopoeia (Zinc Oxide EP), Zinc Oxide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Zinc Oxide USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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