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Chemistry

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Also known as: Phenododecinium, Domiphen cation, Domiphen ion, 13900-14-6, Dodecyl-dimethyl-(2-phenoxyethyl)azanium, 4azl56cu0f
Molecular Formula
C22H40NO+
Molecular Weight
334.6  g/mol
InChI Key
YXUPZGKORWTXID-UHFFFAOYSA-N
FDA UNII
4AZL56CU0F

Zinc6845992
Domiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered antiseptic agent.
1 2D Structure

Zinc6845992

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
dodecyl-dimethyl-(2-phenoxyethyl)azanium
2.1.2 InChI
InChI=1S/C22H40NO/c1-4-5-6-7-8-9-10-11-12-16-19-23(2,3)20-21-24-22-17-14-13-15-18-22/h13-15,17-18H,4-12,16,19-21H2,1-3H3/q+1
2.1.3 InChI Key
YXUPZGKORWTXID-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCCCCCCCCCCC[N+](C)(C)CCOC1=CC=CC=C1
2.2 Other Identifiers
2.2.1 UNII
4AZL56CU0F
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Domiphen Bromide

2. Domiphen Chloride

3. Domiphen Hydroxide

2.3.2 Depositor-Supplied Synonyms

1. Phenododecinium

2. Domiphen Cation

3. Domiphen Ion

4. 13900-14-6

5. Dodecyl-dimethyl-(2-phenoxyethyl)azanium

6. 4azl56cu0f

7. Dodecyldimethyl(2-phenoxyethyl)ammonium

8. 1-dodecanaminium, N,n-dimethyl-n-(2-phenoxyethyl)

9. Ncgc00091010-03

10. Unii-4azl56cu0f

11. Domiphen [vandf]

12. Domiphen [who-dd]

13. Schembl1702653

14. Chembl1187011

15. Dtxsid2048080

16. Yxupzgkorwtxid-uhfffaoysa-

17. Chebi:135978

18. Zinc6845992

19. Stl257462

20. Akos022105914

21. Db11594

22. (beta-phenoxyethyl)dimethyldodecylammonium

23. Ncgc00091010-02

24. Ncgc00091010-04

25. Ncgc00091010-05

26. Dodecyl-dimethyl-(2-phenoxyethyl)ammonium

27. Ab01566921_01

28. Dodecyl-dimethyl-(2-phenoxyethyl)azanium Bromide

29. N,n-dimethyl-n-(2-phenoxyethyl)dodecan-1-aminium

30. (.beta.-phenoxyethyl)dimethyldodecylammonium

31. Q27098012

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 334.6 g/mol
Molecular Formula C22H40NO+
XLogP37.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count15
Exact Mass334.310989899 g/mol
Monoisotopic Mass334.310989899 g/mol
Topological Polar Surface Area9.2 Ų
Heavy Atom Count24
Formal Charge1
Complexity271
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Anti-infective (topical), it is used for the treatment of Acute Infectious Dental Diseases and other conditions.


5 Pharmacology and Biochemistry
5.1 Pharmacology

The efficacy and tolerability of domiphen bromide (domifen bromide), administered at a dosage of 0.5 mg every 4-6 hr in a double-blind placebo controlled study in 31 patients affected by acute infectious dental diseases, are described. After 2 days of treatment with the drug, there was a significant decrease in pain and inflammation. The drug elicited a good response, improved prognosis and reduced the number of days of illness.


5.2 ATC Code

A - Alimentary tract and metabolism

A01 - Stomatological preparations

A01A - Stomatological preparations

A01AB - Antiinfectives and antiseptics for local oral treatment

A01AB06 - Domiphen


5.3 Mechanism of Action

Domiphen bromide is a quaternary antiseptic with actions and uses similar to those of cationic surfactants.


ABOUT THIS PAGE

Zinc6845992 Manufacturers

A Zinc6845992 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Zinc6845992, including repackagers and relabelers. The FDA regulates Zinc6845992 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Zinc6845992 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Zinc6845992 Suppliers

A Zinc6845992 supplier is an individual or a company that provides Zinc6845992 active pharmaceutical ingredient (API) or Zinc6845992 finished formulations upon request. The Zinc6845992 suppliers may include Zinc6845992 API manufacturers, exporters, distributors and traders.

Zinc6845992 GMP

Zinc6845992 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Zinc6845992 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Zinc6845992 GMP manufacturer or Zinc6845992 GMP API supplier for your needs.

Zinc6845992 CoA

A Zinc6845992 CoA (Certificate of Analysis) is a formal document that attests to Zinc6845992's compliance with Zinc6845992 specifications and serves as a tool for batch-level quality control.

Zinc6845992 CoA mostly includes findings from lab analyses of a specific batch. For each Zinc6845992 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Zinc6845992 may be tested according to a variety of international standards, such as European Pharmacopoeia (Zinc6845992 EP), Zinc6845992 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Zinc6845992 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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