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Chemistry

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Also known as:
Molecular Formula
C9H13N5O4
Molecular Weight
255.23  g/mol
InChI Key
IRSCQMHQWWYFCW-UHFFFAOYSA-N

Ganciclovir
1 2D Structure

Ganciclovir

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-3H-purin-6-one
2.1.2 InChI
InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)
2.1.3 InChI Key
IRSCQMHQWWYFCW-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=NC2=C(N1COC(CO)CO)NC(=NC2=O)N
2.1.5 Isomeric SMILES
C1=NC2=C(N1COC(CO)CO)NC(=NC2=O)N
2.2 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 255.23 g/mol
Molecular Formula C9H13N5O4
XLogP3-1.7
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass255.09675391 g/mol
Monoisotopic Mass255.09675391 g/mol
Topological Polar Surface Area135 A^2
Heavy Atom Count18
Formal Charge0
Complexity346
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 6  
Drug NameCytovene
PubMed HealthGanciclovir (Injection)
Drug ClassesAntiviral
Drug LabelGanciclovir is a synthetic guanine derivative active against cytomegalovirus (CMV). CYTOVENE-IV is the brand name for ganciclovir sodium for injection.CYTOVENE-IV is available as sterile lyophilized powder in strength of 500 mg per vial for intraveno...
Active IngredientGanciclovir sodium
Dosage FormInjectable
RouteInjection
Strengtheq 500mg base/vial
Market StatusPrescription
CompanyRoche Palo

2 of 6  
Drug NameGanciclovir
PubMed HealthGanciclovir
Drug ClassesAntiviral
Drug LabelGanciclovir is a synthetic guanine derivative active against cytomegalovirus (CMV).Ganciclovir is available as 250 mg and 500 mg capsules. Each capsule contains 250 mg or 500 mg ganciclovir, USP respectively, and inactive ingredients croscarmellose s...
Active IngredientGanciclovir sodium
Dosage FormInjectable
RouteInjection
Strengtheq 500mg base/vial
Market StatusPrescription
CompanyFresenius Kabi Usa; Luitpold

3 of 6  
Drug NameZirgan
PubMed HealthGanciclovir
Drug ClassesAntiviral
Drug LabelZIRGAN (ganciclovir ophthalmic gel) 0.15% contains a sterile, topical antiviral for ophthalmic use. The chemical name is 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (CAS number 82410-32-0). Ganciclovir is represented by the following structu...
Active IngredientGanciclovir
Dosage FormGel
RouteOphthalmic
Strength0.15%
Market StatusPrescription
CompanyBausch And Lomb

4 of 6  
Drug NameCytovene
PubMed HealthGanciclovir (Injection)
Drug ClassesAntiviral
Drug LabelGanciclovir is a synthetic guanine derivative active against cytomegalovirus (CMV). CYTOVENE-IV is the brand name for ganciclovir sodium for injection.CYTOVENE-IV is available as sterile lyophilized powder in strength of 500 mg per vial for intraveno...
Active IngredientGanciclovir sodium
Dosage FormInjectable
RouteInjection
Strengtheq 500mg base/vial
Market StatusPrescription
CompanyRoche Palo

5 of 6  
Drug NameGanciclovir
PubMed HealthGanciclovir
Drug ClassesAntiviral
Drug LabelGanciclovir is a synthetic guanine derivative active against cytomegalovirus (CMV).Ganciclovir is available as 250 mg and 500 mg capsules. Each capsule contains 250 mg or 500 mg ganciclovir, USP respectively, and inactive ingredients croscarmellose s...
Active IngredientGanciclovir sodium
Dosage FormInjectable
RouteInjection
Strengtheq 500mg base/vial
Market StatusPrescription
CompanyFresenius Kabi Usa; Luitpold

6 of 6  
Drug NameZirgan
PubMed HealthGanciclovir
Drug ClassesAntiviral
Drug LabelZIRGAN (ganciclovir ophthalmic gel) 0.15% contains a sterile, topical antiviral for ophthalmic use. The chemical name is 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (CAS number 82410-32-0). Ganciclovir is represented by the following structu...
Active IngredientGanciclovir
Dosage FormGel
RouteOphthalmic
Strength0.15%
Market StatusPrescription
CompanyBausch And Lomb

API SUPPLIERS

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Hubei Gedian Humanwell Pharmaceuti...

China

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Virtual BoothHubei Gedian Humanwell focuses on R&D, production, & sales of fertility regulation drugs & steroidal APIs.

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Fareva

Luxembourg

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Medlab Asia & Asia Health
Not Confirmed
  • fda
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Virtual BoothFareva is a one-stop-shop for API/HPAPI, OSD & Sterile products, is USFDA, EMA and PMDA-inspected and has multiple NDA & ANDA filings.

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03

CHANGZHOU KONY PHARMACEUTICAL CO.,...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Not Confirmed
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CHANGZHOU KONY PHARMACEUTICAL CO.,...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Aurobindo Pharma Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Aurobindo Pharma Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Trifarma

Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Trifarma

Italy

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RANBAXY LABORATORIES LIMITED

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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RANBAXY LABORATORIES LIMITED

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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07

Charioteer

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Charioteer

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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08

Globe Quimica Ltda

Brazil

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Globe Quimica Ltda

Brazil

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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09

Aspen Biopharma Labs

India

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10

Unimark Remedies Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health
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Unimark Remedies Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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USDMF

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Medlab Asia & Asia Health
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  • EDQM
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Virtual BoothFareva is a one-stop-shop for API/HPAPI, OSD & Sterile products, is USFDA, EMA and PMDA-inspected and has multiple NDA & ANDA filings.

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Digital Content Digital Content

GDUFA

DMF Review : Complete

Rev. Date : 2013-01-30

Pay. Date : 2013-01-08

DMF Number : 15567

Submission : 2001-07-31

Status : Active

Type : II

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02

Medlab Asia & Asia Health
Not Confirmed

02

Medlab Asia & Asia Health
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GDUFA

DMF Review : Complete

Rev. Date : 2017-03-07

Pay. Date : 2017-02-15

DMF Number : 31402

Submission : 2017-02-18

Status : Active

Type : II

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Medlab Asia & Asia Health
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03

Medlab Asia & Asia Health
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GDUFA

DMF Review : Complete

Rev. Date : 2016-06-02

Pay. Date : 2015-08-07

DMF Number : 28973

Submission : 2015-04-02

Status : Active

Type : II

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04

Medlab Asia & Asia Health
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05

Medlab Asia & Asia Health
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05

Medlab Asia & Asia Health
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GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 16043

Submission : 2002-07-08

Status : Inactive

Type : II

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Trifarma Spa

Italy

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API Reference Price

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06-Jan-2021
29-Oct-2024
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