Zoledronate Disodium

Synopsis, Chemistry

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Teva API

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Zoledronate Disodium

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USDMF

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CEP/COS

Japanese DMF

JDMF

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Application Number

32008

Status

Active
Fees Paid
Reviewed

Filing Details

ZOLEDRONATE DISODIUM

Issue/Submission Date

2017-12-31

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Looking for 131654-46-1 / Zoledronate Disodium API manufacturers, exporters & distributors?

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PharmaCompass also assists you with knowing the Zoledronate Disodium API Price utilized in the formulation of products. Zoledronate Disodium API Price is not always fixed or binding as the Zoledronate Disodium Price is obtained through a variety of data sources. The Zoledronate Disodium Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Zoledronate Disodium

Synonyms

Zoledronic acid disodium, Zoledronate disodium anhydrous, 165800-07-7, 5csv5k1879, 131654-46-1, Unii-5csv5k1879

Cas Number

131654-46-1

Unique Ingredient Identifier (UNII)

5CSV5K1879

About Zoledronate Disodium

Zoledronate Disodium is the disodium salt form of zoledronate, a synthetic imidazole, third generation bisphosphonate analog of pyrophosphate with antiresorptive activity. Zoledronate binds to hydroxyapatite crystals in the bone matrix and inhibits farnesyl pyrophosphate (diphosphate) synthase, thereby preventing protein prenylation within the mevalonate pathway. This leads to the loss of downstream metabolites essential for osteoclast function, leading to the induction of apoptosis and eventually, osteoclast-cell death. By preventing osteoclast-mediated bone resorption, zoledronate decreases bone turnover and stabilizes the bone matrix.

Zoledronate Disodium Manufacturers

A Zoledronate Disodium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Zoledronate Disodium, including repackagers and relabelers. The FDA regulates Zoledronate Disodium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Zoledronate Disodium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Zoledronate Disodium Suppliers

A Zoledronate Disodium supplier is an individual or a company that provides Zoledronate Disodium active pharmaceutical ingredient (API) or Zoledronate Disodium finished formulations upon request. The Zoledronate Disodium suppliers may include Zoledronate Disodium API manufacturers, exporters, distributors and traders.

click here to find a list of Zoledronate Disodium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Zoledronate Disodium Manufacturers | Traders | Suppliers

We have 1 companies offering Zoledronate Disodium

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Teva API

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.