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    Company profile for Centrient Pharmaceuticals

    Centrient Pharmaceuticals-PSE
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    Centrient opens Innovation Lab in Barcelona's Product Development

    21 Oct 2024

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    Centrient’s SBTi-Validated Climate Targets Reinforce Commitment

    04 Sep 2024

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    Centrient ESG Report Confirms Continued Leadership Sustainable MFG of Medicines

    24 Jun 2024

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    Centrient Pharmaceuticals

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    Centrient is a leading manufacturer of Beta-Lactam Antibiotics and a provider of next-generation Statins and Antifungals.

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    About

    Established in 1869, Centrient Pharmaceuticals is a global B2B leader in sustainable, enzymatic antibiotics, next-generation statins and anti-fungals. Together with tablets, capsules and finished dosage forms, it manufactures and markets intermediates and active pharmaceutical ingredients (APIs). It is a pharmaceutical company with a clear purpose — to improve lives through innovative and sustainable manufacturing of medicines. Centrient is committed to ensuring quality, reliability and sustainability for its customers, partners and patients. Its vision is to be the leading, diversified and fully integrated partner for generics marketers.

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    Centrient PharmaceuticalsNetherlands1 Flag
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    Netherlands
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    Sir Winston Churchilllaan 299, 2288 DC Rijswijk
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    info@centrient.com
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    INTERVIEW #SpeakPharma

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    “Centrient is at the forefront of sustainable pharmaceutical manufacturing”

    “Centrient is at the forefront of sustainable pharmaceutical manufacturing”

    One of the most pressing problems today is environmental pollution. Every year, the world comes together on April 22 to celebrate Earth Day. This year’s Earth Day calls on governments, institutions, businesses, and citizens to invest in the planet by addressing the issues of climate change, air and water pollution, deforestation, and plastic overconsumption. According to the World Health Organization (WHO), healthier environments can prevent almost a quarter of the world’s disease burden.This week, SpeakPharma spoke to Manjit Singh, Director for Corporate Sustainability at Centrient Pharmaceuticals, a global B2B leader in sustainable, enzymatic antibiotics, next-generation statins and anti-fungals, about sustainable manufacturing.How are pharma companies addressing the issue of environmental sustainability? What goals have you set for reducing your environmental impact?The global pharma industry is a major polluter. During the past decade, the intensity of greenhouse gas emissions generated by the pharma industry was approximately 55 percent greater than that of the automotive industry. The industry must work together to systematically consider the environmental impact of the products it manufactures.Today, many companies incorporate carbon emissions reduction, responsible waste and water management, and renewable energy sourcing as core environmental, social, and governance (ESG) goals. The growing demand for environmental sustainability also affects pharmaceutical companies’ supply chains and procurement practices.One of the biggest environmental issues we face as a society is CO2 emissions. It’s a major focus area for many companies. At Centrient, we have set a goal of reducing our carbon emission intensity by 50 percent by 2030 through increased reliance on renewable energy. We are committed to going through third-party assessments and ratings like EcoVadis and SBTi (Science Based Targets initiative) to be transparent about our progress towards emissions reduction targets.Another key issue is wastewater management. Pharmaceutical manufacturing, particularly antibiotic production, is a highly water-intensive process. We produce all our antibiotics using a proprietary enzymatic process. This process requires less water and energy and doesn’t use chemical solvents or other harmful substances.What is antimicrobial resistance, and how does it affect human health and the environment?Antimicrobial resistance or AMR occurs when bacteria, viruses, fungi, and parasites change over time and stop responding to medicines. Antibiotics and other antimicrobial drugs become ineffective, and infections become increasingly difficult or impossible to treat, making routine medical procedures, such as surgery — including C-sections, hip replacements, and organ transplantations — riskier. For example, AMR is the second leading cause of death in cancer patients.The WHO currently lists AMR among the top 10 threats to global health. By 2050, up to 10 million deaths could occur annually due to AMR.When it comes to pharmaceutical manufacturing, release of antibiotics in high concentrations from manufacturing sites can contribute to new forms of resistance in pathogens. In 2016, we became one of the first pharmaceutical companies to begin the continuous, year-round monitoring of antimicrobial activities in wastewater at all our sites in Europe and beyond. Since then, we have developed an innovative way of detecting very low antibiotic activity levels – as low as 50 parts per billion – in wastewater. In May 2022, we became the first pharma company to meet the stringent PNEC (short for Predicted No-Effect Concentration) discharge targets for our complete oral antibiotics product range and their supply chains. The final step in this process will be to obtain an external PNEC certification.We are one of the first companies to participate in a pilot certification scheme designed by the British Standards Institution (BSI) in collaboration with the AMR Industry Alliance.As a former chair of the Pharmaceutical Supply Chain Initiative (PSCI), what’s your view on the recent developments in sustainable procurement?Along with responsible manufacturing, the industry must ensure that the procured raw materials come from cleaner sources. Some European governmental agencies already incentivize responsible manufacturing and compliance while procuring antibiotics from suppliers. For example, at Centrient, our suppliers are assessed by PSCI-approved audit firms and in-house assessments. This covers labor and human rights, ethics, health and safety, the environment, and management systems.What are your sustainability tips for Earth Day?To make a positive impact on Earth Day, individuals can clean up their communities, plant more trees, reduce the use of plastic, and reuse and recycle more things. Similarly, manufacturers must consider the negative impact of their operations on the environment and make sustainability a part of their business strategy.At Centrient, our sustainability efforts are geared towards creating value for all our stakeholders, driving sustainable growth with our customers, and creating a more sustainable world for future generations. 

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    #SpeakPharma With Centrient Pharmaceuticals
    21 Apr 2023
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    CORPORATE CONTENT #SupplierSpotlight

    Product List 2024

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    Corporate Presentation

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    PNEC White Paper

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    ESG Report

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    GMP Certificate 2019

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    Centrient Acquires Astral SteriTech

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    Centrient Expanding Product Portfolio

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    NEWS #PharmaBuzz

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    Centrient opens Innovation Lab in Barcelona's Product Development
    Centrient opens Innovation Lab in Barcelona's Product Development

    21 Oct 2024

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    https://www.centrient.com/media/centrient-pharmaceuticals-opens-barcelona-innovation-laboratory-accelerate-product-and

    PRESS RELEASE
    21 Oct 2024
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    Centrient’s SBTi-Validated Climate Targets Reinforce Commitment
    Centrient’s SBTi-Validated Climate Targets Reinforce Commitment

    04 Sep 2024

    // PRESS RELEASE

    https://www.centrient.com/media/centrients-sbti-validated-climate-targets-reinforce-environmental-commitment

    PRESS RELEASE
    04 Sep 2024
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    Centrient ESG Report Confirms Continued Leadership Sustainable MFG of Medicines
    Centrient ESG Report Confirms Continued Leadership Sustainable MFG of Medicines

    24 Jun 2024

    // PRESS RELEASE

    https://www.centrient.com/media/centrient-pharmaceuticals-receives-independent-minimized-risk-antimicrobial-resistance-amr

    PRESS RELEASE
    24 Jun 2024
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    Centrient receives independent Minimized Risk of AMR certification Spain Site
    Centrient receives independent Minimized Risk of AMR certification Spain Site

    30 Jan 2024

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    https://www.centrient.com/media/centrient-pharmaceuticals-receives-independent-minimized-risk-antimicrobial-resistance-amr

    PRESS RELEASE
    30 Jan 2024
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    Centrient Pharma Receives Gold Sustainability Rating from EcoVadis
    Centrient Pharma Receives Gold Sustainability Rating from EcoVadis

    09 Jan 2024

    // PRESS RELEASE

    https://www.centrient.com/media/centrient-pharmaceuticals-receives-gold-sustainability-rating-ecovadis-1

    PRESS RELEASE
    09 Jan 2024
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    Bain Capital eyes potential €1B Centrient sale: report
    Bain Capital eyes potential €1B Centrient sale: report

    04 Jan 2024

    // FIERCE PHARMA

    https://www.fiercepharma.com/pharma/bain-capital-eyes-potential-eu1b-sale-dutch-antibiotics-manufacturer-centrient-report

    FIERCE PHARMA
    04 Jan 2024
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    USDMF

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    01

    Amoxicillin Trihydrate (purimox)

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    Virtual BoothCentrient is a leading manufacturer of Beta-Lactam Antibiotics and a provider of next-generation Statins and Antifungals.

    Centrient Pharmaceuticals

    GDUFA

    DMF Review : Complete

    Rev. Date : 2014-06-16

    Pay. Date : 2014-03-05

    DMF Number : 25875

    Submission : 2012-03-16

    Status : Active

    Type : II

    Centrient Pharmaceuticals

    Product
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    02

    Amoxicillin Trihydrate (purimox®)

    Netherlands
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    Antibody Engineering
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    Virtual BoothCentrient is a leading manufacturer of Beta-Lactam Antibiotics and a provider of next-generation Statins and Antifungals.

    Centrient Pharmaceuticals

    GDUFA

    DMF Review : Complete

    Rev. Date : 2013-01-07

    Pay. Date : 2012-12-20

    DMF Number : 16950

    Submission : 2003-11-14

    Status : Active

    Type : II

    Centrient Pharmaceuticals

    Product
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    Stock Recap
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    03

    Ampicillin Trihydrate (puricillin)

    Netherlands
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    Virtual BoothCentrient is a leading manufacturer of Beta-Lactam Antibiotics and a provider of next-generation Statins and Antifungals.

    Centrient Pharmaceuticals

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 26505

    Submission : 2012-10-30

    Status : Active

    Type : II

    Centrient Pharmaceuticals

    Product
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    04

    Atorvastatin Calcium

    Netherlands
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    Virtual BoothCentrient is a leading manufacturer of Beta-Lactam Antibiotics and a provider of next-generation Statins and Antifungals.

    Centrient Pharmaceuticals

    GDUFA

    DMF Review : Complete

    Rev. Date : 2016-05-31

    Pay. Date : 2015-08-20

    DMF Number : 29520

    Submission : 2015-08-03

    Status : Active

    Type : II

    Centrient Pharmaceuticals

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    05

    Cefadroxil Monohydrate Usp (puridrox...

    Netherlands
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    • EDQM
    • WHO-GMP
    Virtual BoothCentrient is a leading manufacturer of Beta-Lactam Antibiotics and a provider of next-generation Statins and Antifungals.

    Centrient Pharmaceuticals

    GDUFA

    DMF Review : Complete

    Rev. Date : 2014-01-22

    Pay. Date : 2013-01-11

    DMF Number : 13749

    Submission : 1998-09-01

    Status : Active

    Type : II

    Centrient Pharmaceuticals

    Product
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    Stock Recap
    #PipelineProspector

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    Place

    06

    Cephalexin Monohydrate

    Netherlands
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    Antibody Engineering
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    • fda
    • EDQM
    • WHO-GMP
    Virtual BoothCentrient is a leading manufacturer of Beta-Lactam Antibiotics and a provider of next-generation Statins and Antifungals.

    Centrient Pharmaceuticals

    GDUFA

    DMF Review : Complete

    Rev. Date : 2013-01-11

    Pay. Date : 2013-01-11

    DMF Number : 13210

    Submission : 1998-04-30

    Status : Active

    Type : II

    Centrient Pharmaceuticals

    Product
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    Stock Recap
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    07

    Nystatin

    Netherlands
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    • EDQM
    • WHO-GMP
    Virtual BoothCentrient is a leading manufacturer of Beta-Lactam Antibiotics and a provider of next-generation Statins and Antifungals.

    Centrient Pharmaceuticals

    GDUFA

    DMF Review : Complete

    Rev. Date : 2013-08-07

    Pay. Date : 2013-07-29

    DMF Number : 13523

    Submission : 1998-09-01

    Status : Active

    Type : II

    Centrient Pharmaceuticals

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    08

    Rosuvastatin Calcium

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    • EDQM
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    Virtual BoothCentrient is a leading manufacturer of Beta-Lactam Antibiotics and a provider of next-generation Statins and Antifungals.

    Centrient Pharmaceuticals

    GDUFA

    DMF Review : Complete

    Rev. Date : 2017-11-17

    Pay. Date : 2017-05-23

    DMF Number : 31410

    Submission : 2017-03-28

    Status : Active

    Type : II

    Centrient Pharmaceuticals

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    KEY PRODUCTS

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    Inspections and registrations

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    FDA

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    FDA Audited

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    District Decision : No Action Indicated

    Inspection End Date : 2012-09-19

    Centrient Pharmaceuticals

    City : Santa Perpetua De Mogoda

    State :

    Country/Area : Spain

    Zip :

    District :

    Center :

    Project Area : Drug Quality Assurance

    District Decision : No Action Indicated

    Inspection End Date : 2012-09-19

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    02

    FDA Audited

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    Antibody Engineering
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    District Decision : Voluntary Action Indicated

    Inspection End Date : 2015-09-25

    Centrient Pharmaceuticals

    City : Santa Perpetua De Mogoda

    State :

    Country/Area : Spain

    Zip :

    District :

    Center :

    Project Area : Drug Quality Assurance

    District Decision : Voluntary Action Indicated

    Inspection End Date : 2015-09-25

    Centrient Pharmaceuticals

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    03

    FDA Audited

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    District Decision : Voluntary Action Indicated

    Inspection End Date : 2015-12-18

    Centrient Pharmaceuticals

    City : Nawashahr

    State :

    Country/Area : India

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    District :

    Center :

    Project Area : Drug Quality Assurance

    District Decision : Voluntary Action Indicated

    Inspection End Date : 2015-12-18

    Centrient Pharmaceuticals

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    04

    FDA Audited

    USA
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    Antibody Engineering
    Not Confirmed

    District Decision : Voluntary Action Indicated

    Inspection End Date : 2019-05-10

    Centrient Pharmaceuticals

    City : Santa Perpetua De Mogoda

    State :

    Country/Area : Spain

    Zip :

    District :

    Center :

    Project Area : Drug Quality Assurance

    District Decision : Voluntary Action Indicated

    Inspection End Date : 2019-05-10

    Centrient Pharmaceuticals

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    05

    FDA Audited

    USA
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    Antibody Engineering
    Not Confirmed

    District Decision : No Action Indicated

    Inspection End Date : 2010-07-15

    Centrient Pharmaceuticals

    City : Santa Perpetua De Mogoda

    State :

    Country/Area : Spain

    Zip :

    District :

    Center :

    Project Area : Drug Quality Assurance

    District Decision : No Action Indicated

    Inspection End Date : 2010-07-15

    Centrient Pharmaceuticals

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    06

    FDA Audited

    USA
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    Antibody Engineering
    Not Confirmed

    District Decision : Voluntary Action Indicated

    Inspection End Date : 2010-01-28

    Astral SteriTech

    City : Vadodara

    State :

    Country/Area : India

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    District :

    Center :

    Project Area : Drug Quality Assurance

    District Decision : Voluntary Action Indicated

    Inspection End Date : 2010-01-28

    Centrient Company Banner

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    07

    FDA Audited

    USA
    arrow
    Antibody Engineering
    Not Confirmed

    District Decision : No Action Indicated

    Inspection End Date : 2012-03-01

    Astral SteriTech

    City : Vadodara

    State :

    Country/Area : India

    Zip :

    District :

    Center :

    Project Area : Drug Quality Assurance

    District Decision : No Action Indicated

    Inspection End Date : 2012-03-01

    Centrient Company Banner

    Product
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    Stock Recap
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    08

    FDA Audited

    USA
    arrow
    Antibody Engineering
    Not Confirmed

    District Decision : Voluntary Action Indicated

    Inspection End Date : 2015-05-11

    Astral SteriTech

    City : Vadodara

    State :

    Country/Area : India

    Zip :

    District :

    Center :

    Project Area : Drug Quality Assurance

    District Decision : Voluntary Action Indicated

    Inspection End Date : 2015-05-11

    Centrient Company Banner

    Product
    Web Link

    Stock Recap
    #PipelineProspector

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    09

    FDA Audited

    USA
    arrow
    Antibody Engineering
    Not Confirmed

    District Decision : No Action Indicated

    Inspection End Date : 2018-04-03

    Astral SteriTech

    City : Vadodara

    State :

    Country/Area : India

    Zip :

    District :

    Center :

    Project Area : Drug Quality Assurance

    District Decision : No Action Indicated

    Inspection End Date : 2018-04-03

    Centrient Company Banner

    Product
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    ABOUT THIS PAGE

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    Centrient Pharmaceuticals is a supplier offers 26 products (APIs, Excipients or Intermediates).

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