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Lupin Ltd
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India
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Kalina, Santacruz East, Mumbai 400 098
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Nextstellis is a novel combination medication comprising of drospirenone (DRSP) and estetrol (E4), indicated for use by women of reproductive age to prevent pregnancy.


Lead Product(s): Drospirenone,Estetrol

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Product Name: Nextstellis

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: OLIC

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement June 12, 2024

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Lupin has completed the acquisition of two well-known brands, Aarane (sodium cromoglicate) in Germany and Nalcrom (cromoglicic acid) in Canada and the Netherlands, from Sanofi.


Lead Product(s): Sodium Cromoglicate,Bronchodil

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: Aarane

Highest Development Status: ApprovedProduct Type: Small molecule

Recipient: Sanofi

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition June 05, 2024

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Rymti (etanercept-biosimilar) is a tumor necrosis factor (TNF) blocker indicated for the treatment of rheumatoid arthritis, polyarticular juvenile idiopathic arthritis in patients aged 2 years or older, psoriatic arthritis, ankylosing spondylitis & plaque psoriasis.


Lead Product(s): Etanercept

Therapeutic Area: Immunology Product Name: Rymti

Highest Development Status: ApprovedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Sandoz B2B

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 03, 2024

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Ganirelix Acetate-Generic is a synthetic decapeptide with high antagonistic 6 activity against naturally occurring GnRH. It is indicated for the inhibition of premature LH surges in women undergoing controlled ovarian hyperstimulation.


Lead Product(s): Ganirelix

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Product Name: Ganirelix Acetate-Generic

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 15, 2024

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BromSite-Generic (bromfenac) acts by inhibiting Cox-1 and 2. It is indicated for the treatment of postoperative inflammation and prevention of ocular pain in patients undergoing cataract surgery.


Lead Product(s): Bromfenac

Therapeutic Area: Ophthalmology Product Name: BromSite-Generic

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 14, 2024

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Inderal-Generic (propranolol) is a β-adrenoceptors antagonist. It is now approved for the treatment of hypertension, angina pectoris, migraine, hypertrophic subaortic stenosis.


Lead Product(s): Propranolol Hydrochloride

Therapeutic Area: Cardiology/Vascular Diseases Product Name: Inderal-Generic

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 14, 2024

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RLD Chantix (varenicline) is a nAChRα4&β2 (Neuronal acetylcholine receptor; alpha4/beta2) agonist, small molecule drug. It is approved for the treatment of smoking cessation.


Lead Product(s): Varenicline Tartrate

Therapeutic Area: Psychiatry/Psychology Product Name: RLD Chantix

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 06, 2024

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Through th acquisition, Lupin expand its portfolio of accretive established products in Europe and Canada, including Xopenex (levalbuterol HCl), a short-acting β₂ adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease.


Lead Product(s): Levalbuterol Hydrochloride

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: Xopenex

Highest Development Status: ApprovedProduct Type: Small molecule

Recipient: Sanofi

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition December 23, 2023

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Vilfuro-G (vilanterol, fluticasone furoate & glycopyrronium bromide) is world's first fixed-dose triple combination drug which is approved for the treatment of chronic obstructive pulmonary disease (COPD).


Lead Product(s): Vilanterol Trifenatate,Fluticasone Furoate,Glycopyrronium Bromide

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: Vilfuro-G

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 23, 2023

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Fluconazole, the first of a new subclass of synthetic triazole antifungal agents, is available as tablets for oral administration, which is indicated for the treatment of Vaginal candidiasis.


Lead Product(s): Fluconazole

Therapeutic Area: Infections and Infectious Diseases Product Name: Diflucan-Generic

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 25, 2023

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