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    About

    Mallinckrodt Pharmaceuticals is a multibillion dollar specialty biopharmaceutical company focused on our mission: Managing Complexity. Improving Lives. We provide medicines to address unmet patient needs, steming from nearly 150 years of using our unique strengths, experience and expertise to help improve people’s lives. Discover how our rich history of innovation and patient-centered solutions has helped influence our visio...
    Mallinckrodt Pharmaceuticals is a multibillion dollar specialty biopharmaceutical company focused on our mission: Managing Complexity. Improving Lives. We provide medicines to address unmet patient needs, steming from nearly 150 years of using our unique strengths, experience and expertise to help improve people’s lives. Discover how our rich history of innovation and patient-centered solutions has helped influence our vision for the future. Our strong ability to master and manage complexity is the key component in making high-quality products that provide value for patients.

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    INTERVIEW #SpeakPharma

    [Sponsored by another company]
    “LGM Pharma has made significant strides in meeting the evolving needs of its clients”

    “LGM Pharma has made significant strides in meeting the evolving needs of its clients”

    This week, SpeakPharma interviews four senior executives of LGM Pharma — Shailesh Vengurlekar (Senior VP, Quality and Regulatory Affairs), Deepak Thassu (Senior VP, R&D and Regulatory Submission), Selwyn Lustman (Senior VP, Global Sourcing and Procurement), and Mike Stenberg (VP, Business Development). The four VPs talk about expansion in manufacturing capabilities of the Florida-based contract development and manufacturing organization (CDMO), expertise that makes LGM a strong partner and the criteria it adopts while selecting its suppliers.  HIGHLIGHTS// expansion in manufacturing capabilities/ expertise that makes LGM a strong partner/ criteria for selecting its suppliers LGM Pharma recently invested heavily in expanding its CDMO capabilities by 50 percent. Can you share why offering standalone analytical testing services is important to LGM Pharma’s growth strategy? How does it benefit your clients? Vengurlekar: This recent expansion in CDMO capabilities is part of LGM Pharma’s growth strategy that lays importance on diversification. One key area of this diversification is the offering of standalone Analytical Testing Services (ATS). This service plays a crucial role in supporting our clients by providing them with greater flexibility and reliability. LGM Pharma is already a well-established leader in the API supply chain. We have now identified a significant need in the market and are now serving compounding pharmacies, including 503A and 503B facilities. These pharmacies not only require high-quality, GMP-compliant APIs, but also need a trusted, compliant, and capable laboratory to analyze both their APIs and compounded products. Recognizing this opportunity to further support our clients, LGM Pharma has expanded into ATS. We have witnessed tremendous growth since we’ve launched these services. By offering ATS under a separate legal entity — LGM Pharma Solutions — we are able to provide an additional layer of flexibility to our clients. This structure eliminates any conflict of interest. While LGM Pharma LLC handles API supply, LGM Pharma Solutions focuses on delivering top-tier ATS, all under the same LGM Pharma umbrella. This setup enhances trust and allows our clients to work with us more seamlessly. HIGHLIGHTS// diversified into standalone ATS/ well-established leader in API supply chain/ serving compounding pharmacies/ offering APIs and ATS under different legal entities. While suppositories offer clear advantages for certain medications, can you describe how LGM Pharma plans to leverage its expertise in this area to address specific unmet needs in the growing women’s health market? Thassu: We’re taking a dual approach to enhance both our R&D and manufacturing capabilities. First, we’ve introduced a new semi-automatic machine that allows us to produce smaller batches more efficiently. This is particularly important for the suppository segment, where demand doesn’t require large-scale production. The new system enables quicker adjustments to the manufacturing process, providing us with greater flexibility of producing small batches. Second, many of the materials we handle in the women’s health sector are sensitive to heat, light, and oxygen. To address this, we’re upgrading our facility to accommodate these specialized requirements. This ensures we can develop and manufacture products while maintaining the integrity of heat-, light-, and oxygen-sensitive ingredients. Additionally, we’re working closely with clients to prepare for various technical challenges. Whether it’s processing homeopathic ingredients or handling delicate fermentation-based materials, which are highly sensitive to both light and heat, our team has upgraded its skills and equipment to manage these complexities. From technology advancements in manufacturing to specialized handling conditions and improved technical expertise, we’ve made significant strides to ensure we can meet the evolving needs of our clients and their products. HIGHLIGHTS// dual approach to enhance R&D and manufacturing capabilities/ upgrading facilities to accommodate specialized requirements/ working with clients to address challenges. The pandemic underscored supply chain problems. Can you detail the specific criteria LGM Pharma uses while selecting suppliers for its manufacturing processes? Lustman: LGM looks at many facets of a manufacturer before proceeding to approve them for a specific project. We start by checking their regulatory history with the US Food and Drug Administration (FDA) and other authorities. We try to find out if they have received any warning letters. What is their inspection history? Have they received NAIs (no action indicated) and VAIs (voluntary action indicated)? We further investigate the company’s overall business status — we need to know that they are a stable partner to work with in the long term. Manufacturers are then assessed for their overall technology and the number of employees working in various fields, such as R&D, quality control, quality assurance, regulatory affairs, manufacturing, and the educational levels of these employees. Once we have established that the manufacturer is a potential partner, we check their status for a particular project. We look at their advantages, and whether they have a non-infringing route of synthesis (ROS) that will allow early launch. Are they developing a second process that will be more competitive in pricing? And, does the manufacturer have the necessary capacity and/or spare capacity for the project that we are assessing? We need to know whether the drug master file (DMF) has been registered, the current batch size, and the potential for increase in batch size. Pricing is a key indicator — we need to know whether the pricing of the manufacturer is competitive or not, and if the manufacturer will be able to compete in the future as the project matures. LGM always assesses for quality, price, and delivery. Goods must be of the correct quality, at the right price, with delivery time as desired, in order to meet commercial needs. HIGHLIGHTS// investigate various facets of manufacturer before approving them for a project/ look at advantages, non-infringing ROS/ assess for quality, price, delivery Can you highlight specific capabilities and experiences LGM Pharma possesses that make it a strong partner for companies developing antibody-drug-conjugates (ADCs)? Stenberg: ADCs are often peptides linked with small molecules. However, they may also be peptides linked with oligonucleotides. Regardless, LGM can help manage the supply chain associated with the components that are used in the conjugation of the ADC. LGM has extensive experience, and an extensive network around sourcing and managing the supply chain associated with ADC components. LGM’s experience and capabilities extend to sourcing peptides, small molecules or oligonucleotides used in the conjugation process. Additionally, given our deep relationships in the supply chain aspect of this process, LGM may also be able to identify partners who can help with the conjugation process itself. HIGHLIGHTS// extensive experience, network around sourcing, managing supply chain associated with ADC components / identify partners that can help with conjugation process

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    09 Nov 2024
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    DATA COMPILATION #PharmaFlow

    [Sponsored by another company]
    Chinese FDA-registered generic facilities gain steam, India maintains lead with 396 facilities

    Chinese FDA-registered generic facilities gain steam, India maintains lead with 396 facilities

    Every year, the US Food and Drug Administration (FDA) publishes the user fee amounts it will collect from manufacturers of pharmaceuticals, generic drugs, biosimilars and medical devices in the coming financial year. The fee for fiscal year 2025 under the Generic Drug User Fee Act (GDUFA) was published on July 31, 2024.The GDUFA, established in 2012, authorizes FDA to assess and collect fees from drug manufacturers to expedite the delivery of safe, high-quality, and affordable generic drugs to the American public.The FDA’s facility payments list under GDUFA reveals that as of November 14, 2024, 1,397 facilities had paid their registration fees for financial year 2025. Of these facilities, 707 or 50.6 percent are active pharmaceutical ingredients (API) facilities, 405 or 29 percent are finished dosage forms (FDF) facilities, 69 (4.9 percent) are facilities that produce both APIs and FDFs, and 216 (15.5 percent) are contract manufacturing services (CMO) sites.Teva Pharmaceuticals, with 29 facility registrations, led the list of companies, followed by Aurobindo Pharma, Sun Pharma, and Dr. Reddy's Laboratories. Fiscal year Facility Registrations 2016 1,425 2017 1,442 2018 1,269 2019 1,286 2020 1,300 2021 1,340 2022 1,385 2023 1,394 2024 1,447 2025 1,397  Generic Drug Facilities Registered with the US FDA for FY2025 (Free Excel Available)India continues to lead with 396 facilities, US and China follow India maintains its dominance in total facility registrations with the FDA, registering 396 facilities for FY2025. This includes 214 API facilities, 135 FDF facilities, 21 facilities engaged in both API and FDF activities, and 26 CMO facilities.The United States holds the second position with 328 facilities, while China strengthened its third position with 197 facilities.With 214 API facilities, India continues to have the largest share of API manufacturing sites, outmatching the combined total of China (128) and the US (83), which together account for 211 facilities. Among European manufacturers, Italy leads with 59 API manufacturing sites, followed by Spain (30) and Germany (25).The US has maintained its lead in FDF facilities with 143 sites, followed closely by India with 135 sites and China with 45 sites. Country API FDF Both CMO Total India 214 135 21 26 396 US 83 143 13 89 328 China 128 45 12 12 197 Italy 59 3 2 19 83 Germany 25 4 1 15 45 Spain 30 9 1 4 44 Canada 7 17   13 37 Taiwan 9 6 5 4 24 Switzerland 15 4   4 23 France 16     6 22 Japan 18   1   19 United Kingdom 12 1   2 15 Mexico 9 1   1 11 Ireland 5 5   1 11   Generic Drug Facilities Registered with the US FDA for FY2025 (Free Excel Available) GDUFA III user fee rates increase across categories for FY25The GDUFA, which was reauthorized on September 30, 2022 (as GDUFA III), continues with provisions that will last until September 30, 2027. In July 2024, the FDA published updated user fee rates for FY2025.The facility fees have seen increases across all categories. API facility fees increased by 3 percent for domestic sites (to US$ 41,580) and 2 percent for foreign sites (to US$ 56,580). FDF facility fees rose by 5 percent for both domestic (to US$ 231,952) and foreign sites (to US$ 246,952). CMO facility fees increased by 5 percent for domestic sites (to US$ 55,668) and 4 percent for foreign sites (to US$ 70,668).Additionally, the fee for large-, medium- and small-sized drug applicants has increased by over 9 percent, compared to the 7 percent increase seen in 2023. Generic Drug Facilities Registered with the US FDA for FY2025 (Free Excel Available) China leads new facility registrations as FDA records 41 new units in FY25Out of the total 1,397 facilities registered for FY2025, 41 were new registrations (going by Facility FDA Establishment Identifier numbers). China led the way with 13 new facilities, followed closely by India with 11 new facilities, while the US secured the third position with eight new facilities.The new registrations included 15 API facilities, 13 CMO facilities, 12 FDF facilities, and one facility engaged in both API and FDF activities. Chinese companies dominated the new FDF registrations with six facilities: Chengdu Shuode Pharma, Chengdu Suncadia Medicine, Cipla (Jiangsu), GE Healthcare (Shanghai), Luoxin Aurovitas Pharma (Chengdu), and Zhejiang Xianju Pharma.India added two new FDF facilities through Eugia Steriles and Zydus Pharma. Malaysia registered two FDF facilities through Novugen Pharma and Novugen Oncology, while Turkey’s Insud Pharma subsidiary Exeltis and US’ RK Pharma registered one FDF facility each.The 13 new CMO facilities included, Acme Generics, Emcure, Esjay Pharma, Fordoz Pharma, Fourrts Laboratories, Laboratoires KABS, PharmaMax, Quality Packaging Specialists International, Ritsa Pharma, Shanghai Aucyun Pharma, Sichuan Huiyu Pharma, Taejoon Pharm, and Tubilux Pharma.In the API category, the 15 new registrations included Acharya Chemicals, Hainan Poly Pharma, CBL Patras, EUROAPI, Hybio Pharma, Medilux Laboratories, Metrochem API, Purolite, Chengdu Easton Biopharma, Sionc Pharma, Smithfield Bioscience, Xttrium Laboratories, Zhejiang Hengkang Pharma, Moehs Iberica and Shilpa Pharma. Armstrong Pharmaceuticals registered the sole facility for both APIs and FDFs.So far, 92 facilities have not renewed their registration. Among these was a facility owned by Sandoz subsidiary Eon Labs in Wilson, North Carolina (US), which is permanently closed. In fact, the geographical distribution of non-renewals shows that 30 facilities were from the US, while India and China accounted for 14 and nine non-renewals respectively. Generic Drug Facilities Registered with the US FDA for FY2025 (Free Excel Available) Our viewThe FY 2025 GDUFA facility registration data indicates a continued strong presence of Indian manufacturers in the US generic drug market, particularly in API production. However, China's leadership in new facility registrations, especially in FDF manufacturing, suggests that the global generic drug supply chain landscape may evolve considerably in the coming years. 
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    21 Nov 2024
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    NEWS #PharmaBuzz

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    Mallinckrodt Presents Data on TERLIVAZ® for Hepatorenal Syndrome
    Mallinckrodt Presents Data on TERLIVAZ® for Hepatorenal Syndrome

    18 Nov 2024

    // PR NEWSWIRE

    https://www.prnewswire.com/news-releases/mallinckrodt-presents-data-on-terlivaz-terlipressin-for-injection-in-patients-with-hepatorenal-syndrome-hrs-at-the-2024-american-association-for-the-study-of-liver-diseases-aasld-annual-meeting-302308532.html

    PR NEWSWIRE
    18 Nov 2024
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    Mallinckrodt to Present at Jefferies London Healthcare Conference
    Mallinckrodt to Present at Jefferies London Healthcare Conference

    14 Nov 2024

    // PR NEWSWIRE

    https://www.prnewswire.com/news-releases/mallinckrodt-to-present-at-jefferies-london-healthcare-conference-302305741.html

    PR NEWSWIRE
    14 Nov 2024
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    Mallinckrodt Reports Q3 2024 Results & Full-Year Guidance
    Mallinckrodt Reports Q3 2024 Results & Full-Year Guidance

    05 Nov 2024

    // PR NEWSWIRE

    https://www.prnewswire.com/news-releases/mallinckrodt-plc-reports-third-quarter-2024-financial-results-and-raises-full-year-guidance-302296022.html

    PR NEWSWIRE
    05 Nov 2024
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    Mallinckrodt to Present TERLIVAZ® Data at AASLD Annual Meeting
    Mallinckrodt to Present TERLIVAZ® Data at AASLD Annual Meeting

    30 Oct 2024

    // PR NEWSWIRE

    https://www.prnewswire.com/news-releases/mallinckrodt-to-present-data-on-terlivaz-terlipressin-for-injection-at-the-2024-american-association-for-the-study-of-liver-diseases-aasld-annual-meeting-302290775.html

    PR NEWSWIRE
    30 Oct 2024
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    Mallinckrodt Presents Terlivaz® Data For Hepatorenal Syndrome
    Mallinckrodt Presents Terlivaz® Data For Hepatorenal Syndrome

    29 Oct 2024

    // PR NEWSWIRE

    https://www.prnewswire.com/news-releases/mallinckrodt-presents-data-on-terlivaz-terlipressin-for-injection-in-patients-with-hepatorenal-syndrome-acute-kidney-injury-hrs-aki-at-the-american-college-of-gastroenterology-acg-annual-meeting-302289140.html

    PR NEWSWIRE
    29 Oct 2024
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    Mallinckrodt Presents TERLIVAZ® Data in Hepatorenal Syndrome
    Mallinckrodt Presents TERLIVAZ® Data in Hepatorenal Syndrome

    26 Oct 2024

    // PR NEWSWIRE

    https://www.prnewswire.com/news-releases/mallinckrodt-presents-data-on-terlivaz-terlipressin-for-injection-in-patients-with-hepatorenal-syndrome-hrs-at-kidney-week-2024-302287903.html

    PR NEWSWIRE
    26 Oct 2024
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    ALL APIs

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    01

    Paracetamol

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Pharmtech & Ingredients
    Not Confirmed
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    Paracetamol

    Ireland

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    Pharmtech & Ingredients
    Not Confirmed
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    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
    USDMF arrow-down Click Us! arrow-down
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 4203

    Submission : 1981-06-12

    Status : Active

    Type : II

     CEP/COS arrow-down
    ✖

    Certificate Number : R1-CEP 1996-039 - Rev 04

    Issue Date : 2018-04-25

    Type : Chemical

    Substance Number : 49

    Status : Valid

     JDMF arrow-down
    ✖

    Registration Number : 218MF10905

    Registrant's Address : 385 Marshall Ave, Webster Groves, Missouri 63119, United States

    Initial Date of Registration : 2006-11-10

    Latest Date of Registration :

    EU-WC NDC arrow-down
    ✖

    NDC Package Code : 0406-0046

    Start Marketing Date : 2013-02-19

    End Marketing Date : 2024-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

    KDMF arrow-down
    ✖

    Registrant Name : Johnson & Johnson Korea Sales Co., Ltd.

    Registration Date : 2023-01-10

    Registration Number : 20050831-32-C-126-07(A)

    Manufacturer Name : SpecGx LLC

    Manufacturer Address : 8801 Capital Boulevard, Raleigh, North Carolina 27616, USA

     VMF Others AUDIT
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    02

    Fentanyl

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Pharmtech & Ingredients
    Not Confirmed
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    Fentanyl

    Ireland

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    Pharmtech & Ingredients
    Not Confirmed
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    USDMF Inactive-api
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 8074

    Submission : 1989-05-11

    Status : Inactive

    Type : II

     CEP/COS arrow-down
    ✖

    Certificate Number : CEP 2005-260 - Rev 03

    Issue Date : 2024-02-14

    Type : Chemical

    Substance Number : 1210

    Status : Valid

     JDMF arrow-down
    ✖

    Registration Number : 221MF10283

    Registrant's Address : 385 Marshall Ave, Webster Groves, Missouri 63119, United States

    Initial Date of Registration : 2009-12-22

    Latest Date of Registration :

    EU-WC NDC arrow-down
    ✖

    NDC Package Code : 0406-0129

    Start Marketing Date : 1994-09-30

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

    KDMF arrow-down
    ✖

    Registrant Name : Nosa Chemical Co., Ltd.

    Registration Date : 2022-11-28

    Registration Number : 20221128-211-J-1415

    Manufacturer Name : SpecGx LLC

    Manufacturer Address : 3600 North 2nd Street, St. Louis, MO 63147, USA

     VMF Others AUDIT
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    03

    Fentanyl Citrate

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Pharmtech & Ingredients
    Not Confirmed
    arrow

    Fentanyl Citrate

    Ireland

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    Pharmtech & Ingredients
    Not Confirmed
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    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
    USDMF Inactive-api
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 7051

    Submission : 1987-07-02

    Status : Inactive

    Type : II

     CEP/COS arrow-down
    ✖

    Certificate Number : CEP 2009-097 - Rev 02

    Issue Date : 2024-01-30

    Type : Chemical

    Substance Number : 1103

    Status : Valid

     JDMF arrow-down
    ✖

    Registration Number : 229MF10161

    Registrant's Address : 385 Marshall Ave, Webster Groves, Missouri 63119, United States

    Initial Date of Registration : 2017-08-17

    Latest Date of Registration :

    EU-WC NDC arrow-down
    ✖

    NDC Package Code : 0406-1130

    Start Marketing Date : 1996-06-30

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

    KDMF VMF Others AUDIT
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    04

    Amphetamine

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Pharmtech & Ingredients
    Not Confirmed
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    Amphetamine

    Ireland

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    Pharmtech & Ingredients
    Not Confirmed
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    USDMF arrow-down
    ✖

    GDUFA

    DMF Review : Reviewed

    Rev. Date : 2013-03-17

    Pay. Date : 2013-03-11

    DMF Number : 15385

    Submission : 2001-04-18

    Status : Active

    Type : II

     CEP/COS arrow-down
    ✖

    Certificate Number : R0-CEP 2020-076 - Rev 00

    Issue Date : 2021-07-26

    Type : Chemical

    Substance Number : 2752

    Status : Valid

     JDMF EU-WC NDC arrow-down
    ✖

    NDC Package Code : 0406-1950

    Start Marketing Date : 2013-04-29

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

    KDMF VMF Others AUDIT
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    05

    Buprenorphine Hydrochloride

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Pharmtech & Ingredients
    Not Confirmed
    arrow

    Buprenorphine Hydrochloride

    Ireland

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    Pharmtech & Ingredients
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
    USDMF arrow-down
    ✖

    GDUFA

    DMF Review : Reviewed

    Rev. Date : 2013-07-30

    Pay. Date : 2012-11-30

    DMF Number : 24927

    Submission : 2012-05-02

    Status : Active

    Type : II

     CEP/COS arrow-down
    ✖

    Certificate Number : R1-CEP 2013-048 - Rev 00

    Issue Date : 2021-05-04

    Type : Chemical

    Substance Number : 1181

    Status : Valid

     JDMF EU-WC NDC arrow-down
    ✖

    NDC Package Code : 0406-2910

    Start Marketing Date : 2011-12-17

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

    KDMF VMF Others AUDIT
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    #PipelineProspector

    Market
    Place

    06

    Fentanyl Citrate

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Pharmtech & Ingredients
    Not Confirmed
    arrow

    Fentanyl Citrate

    Ireland

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    Pharmtech & Ingredients
    Not Confirmed
    • fda
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    USDMF arrow-down
    ✖

    GDUFA

    DMF Review : Reviewed

    Rev. Date : 2013-02-12

    Pay. Date : 2012-11-27

    DMF Number : 10128

    Submission : 1993-03-15

    Status : Active

    Type : II

     CEP/COS JDMF arrow-down
    ✖

    Registration Number : 218MF10580

    Registrant's Address : 385 Marshall Ave, Webster Groves, Missouri 63119, United States

    Initial Date of Registration : 2006-06-22

    Latest Date of Registration :

    EU-WC NDC arrow-down
    ✖

    NDC Package Code : 0406-1130

    Start Marketing Date : 1996-06-30

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

    KDMF VMF Others AUDIT
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    07

    Methylphenidate Hydrochloride

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Pharmtech & Ingredients
    Not Confirmed
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    Methylphenidate Hydrochloride

    Ireland

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    Pharmtech & Ingredients
    Not Confirmed
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    GDUFA

    DMF Review : Reviewed

    Rev. Date : 2013-02-08

    Pay. Date : 2012-11-27

    DMF Number : 12769

    Submission : 1997-11-25

    Status : Active

    Type : II

     CEP/COS arrow-down
    ✖

    Certificate Number : CEP 2020-005 - Rev 01

    Issue Date : 2024-10-17

    Type : Chemical

    Substance Number : 2235

    Status : Valid

     JDMF EU-WC NDC arrow-down
    ✖

    NDC Package Code : 0406-0570

    Start Marketing Date : 2014-01-01

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

    KDMF arrow-down
    ✖

    Registrant Name : Korea Pharma Co., Ltd.

    Registration Date : 2023-10-26

    Registration Number : 20231012-209-J-1551(A)

    Manufacturer Name : SpecGx LLC

    Manufacturer Address : 3600 North Second Street, St, Louis, Missouri 63147, USA

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    08

    Naloxone Hydrochloride

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Pharmtech & Ingredients
    Not Confirmed
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    Naloxone Hydrochloride

    Ireland

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    GDUFA

    DMF Review : Reviewed

    Rev. Date : 2013-01-11

    Pay. Date : 2012-12-07

    DMF Number : 1862

    Submission : 1972-01-25

    Status : Active

    Type : II

     CEP/COS arrow-down
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    Certificate Number : R1-CEP 2009-294 - Rev 01

    Issue Date : 2023-08-08

    Type : Chemical

    Substance Number : 729

    Status : Valid

     JDMF EU-WC NDC arrow-down
    ✖

    NDC Package Code : 0406-1492

    Start Marketing Date : 2013-04-01

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

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    09

    Pethidine Hydrochloride

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Pharmtech & Ingredients
    Not Confirmed
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    Pethidine Hydrochloride

    Ireland

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    Pharmtech & Ingredients
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    GDUFA

    DMF Review : Reviewed

    Rev. Date : 2014-08-01

    Pay. Date : 2014-07-28

    DMF Number : 11345

    Submission : 1995-02-10

    Status : Active

    Type : II

     CEP/COS JDMF arrow-down
    ✖

    Registration Number : 218MF10904

    Registrant's Address : 385 Marshall Ave, Webster Groves, Missouri 63119, United States

    Initial Date of Registration : 2006-11-10

    Latest Date of Registration :

    EU-WC NDC arrow-down
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    NDC Package Code : 0406-1585

    Start Marketing Date : 2013-11-20

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

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    10

    Sufentanil Citrate

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Pharmtech & Ingredients
    Not Confirmed
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    Sufentanil Citrate

    Ireland

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 12183

    Submission : 1996-10-21

    Status : Active

    Type : II

     CEP/COS arrow-down
    ✖

    Certificate Number : CEP 2017-095 - Rev 01

    Issue Date : 2024-05-06

    Type : Chemical

    Substance Number : 1269

    Status : Valid

     JDMF EU-WC NDC arrow-down
    ✖

    NDC Package Code : 0406-0310

    Start Marketing Date : 2013-04-01

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1g/g)

    Marketing Category : BULK INGREDIENT

    KDMF arrow-down
    ✖

    Registrant Name : Nosa Chemical Co., Ltd.

    Registration Date : 2022-05-18

    Registration Number : 20220518-210-J-1301

    Manufacturer Name : SpecGx LLC

    Manufacturer Address : 3600 North 2nd Street, St. Louis, MO 63147, USA

     VMF Others AUDIT
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    USDMF

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    01

    6-beta-naltrexol Hydrochloride

    Ireland
    BioFlorida Conference
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    02

    Abx And Cbx Bonded Phase Silica Gels

    Ireland
    BioFlorida Conference
    Not Confirmed
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    03

    Accurbron, S.r. (controlled Release ...

    Ireland
    BioFlorida Conference
    Not Confirmed
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    04

    Acetaminophen

    Ireland
    BioFlorida Conference
    Not Confirmed
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    05

    Acetaminophen Controlled-release Bea...

    Ireland
    BioFlorida Conference
    Not Confirmed
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    06

    Acetaminophen Usp

    Ireland
    BioFlorida Conference
    Not Confirmed
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    07

    Acetoxyacetyl Chloride

    Ireland
    BioFlorida Conference
    Not Confirmed
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    08

    Acetoxyacetyl Chloride

    Ireland
    BioFlorida Conference
    Not Confirmed
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    09

    Actifed S.a. Brand Of Pseudoephedrin...

    Ireland
    BioFlorida Conference
    Not Confirmed
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    10

    Acyclovir Usp (micronized), Coded 25...

    Ireland
    BioFlorida Conference
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    GDUFA

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    GDUFA fees paid

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    Mallinckrodt Pharmaceuticals

    API Manufacturer :

    FDF Manufacturer : FDF MANUFACTURE

    Facility Name : Liebel-Flarsheim Company LLC

    Business Address : 8800 Durant Road Raleigh NC ...

    FEI Number : 1028892

    Country : Ireland

    Paid in : 2019

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    GDUFA fees paid

    USA
    BioFlorida Conference
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    GDUFA fees paid

    USA
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    BioFlorida Conference
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    Mallinckrodt Pharmaceuticals

    API Manufacturer : API MANUFACTURE

    FDF Manufacturer : FDF MANUFACTURE

    Facility Name : Mallinckrodt Nuclear Medicine ...

    Business Address : 2703 Wagner Place Maryland H...

    FEI Number : 1946929

    Country : Ireland

    Paid in : 2019

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    03

    GDUFA fees paid

    USA
    BioFlorida Conference
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    GDUFA fees paid

    USA
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    BioFlorida Conference
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    Mallinckrodt Pharmaceuticals

    API Manufacturer : API MANUFACTURE

    FDF Manufacturer : FDF MANUFACTURE

    Facility Name : SpecGx LLC - Greenville

    Business Address : 100 Louis Latzer Dr. Greenvi...

    FEI Number : 1419579

    Country : Ireland

    Paid in : 2019

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    GDUFA fees paid

    USA
    BioFlorida Conference
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    GDUFA fees paid

    USA
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    BioFlorida Conference
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    Mallinckrodt Pharmaceuticals

    API Manufacturer :

    FDF Manufacturer : FDF MANUFACTURE

    Facility Name : SpecGx LLC - Hobart

    Business Address : 172 Railroad Avenue P.O. Box...

    FEI Number : 1317295

    Country : Ireland

    Paid in : 2019

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    GDUFA fees paid

    USA
    BioFlorida Conference
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    USA
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    Mallinckrodt Pharmaceuticals

    API Manufacturer : API MANUFACTURE

    FDF Manufacturer :

    Facility Name : SpecGx LLC - Raleigh, North Ca...

    Business Address : 8801 Capital Blvd. Raleigh N...

    FEI Number : 1021320

    Country : Ireland

    Paid in : 2019

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    GDUFA fees paid

    USA
    BioFlorida Conference
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    GDUFA fees paid

    USA
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    Mallinckrodt Pharmaceuticals

    API Manufacturer : API MANUFACTURE

    FDF Manufacturer : FDF MANUFACTURE

    Facility Name : SpecGx LLC - St. Louis Plant (...

    Business Address : 3600 N. 2nd Street St. Louis...

    FEI Number : 1940521

    Country : Ireland

    Paid in : 2019

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