Company profile for Orion Corporation

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About

Orion is a globally operating Finnish pharmaceutical company - a builder of well-being. Orion develops, manufactures and markets human and veterinary pharmaceuticals and active pharmaceutical ingredients. The company is continuously developing new drugs and treatment methods. The core therapy areas of Orion's pharmaceutical R&D are neurological disorders, oncology and respiratory diseases for which Orion develops inhaled pulmonary medication. Orion's customers are mainly healthcare service providers and professionals such as specialist and general practitioners, veterinarians, pharmacies, hospitals, healthcare centres, clinics, etc.

CONTACT DETAILS

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Country
Country
Finland
Address
Address
Head officeOrion CorporationOrionintie 1A, FI-02200 Espoo, FinlandP.O.Box 65, ...
Telephone
Telephone
+358 10 4261
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YouTube
Twitter
Twitter
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NEWS #PharmaBuzz

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https://www.orion.fi/en/newsroom/all-news/releases/stock-releases/2024/inside-information-orion-upgrades-full-year-outlook-for-2024/

PRESS RELEASE
15 Jan 2025

https://www.orion.fi/en/newsroom/all-news/releases/stock-releases/2025/recommendation-by-the-orion-nomination-committee-on-the-proposals-to-be-submitted-to-the-2025-annual-general-meeting/

PRESS RELEASE
15 Jan 2025

https://www.orion.fi/en/newsroom/all-news/releases/stock-releases/2025/79345-orion-corporation-a-shares-converted-into-b-shares/#:~:text=In%20accordance%20with%20Section%203,Register%20on%2013%20January%202025.

PRESS RELEASE
13 Jan 2025

https://www.orion.fi/en/newsroom/all-news/releases/press-releases/2025/orions-collaboration-partner-bayer-submits-application-in-china-for-third-indication-of-darolutamide/

PRESS RELEASE
08 Jan 2025

https://www.orion.fi/en/newsroom/all-news/releases/press-releases/2024/orion-and-marinus-terminate-agreement-for-ganaxolone-in-europe/

PRESS RELEASE
02 Jan 2025

https://www.orion.fi/en/newsroom/all-news/releases/press-releases/2024/orion-and-marinus-terminate-agreement-for-ganaxolone-in-europe/

#N/A
30 Dec 2024

Drugs in Development

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Details:

The collaboration combines Abilita's strength in discovering breakthrough antibody therapeutics for challenging membrane protein targets with Orion's proven expertise in oncology, pain.


Lead Product(s): Antibody

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: DiscoveryProduct Type: Large molecule

Recipient: Abilita Therapeutics

Deal Size: $785.0 million Upfront Cash: Undisclosed

Deal Type: Collaboration December 18, 2024

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01

VMX
Not Confirmed

Details : The collaboration combines Abilita's strength in discovering breakthrough antibody therapeutics for challenging membrane protein targets with Orion's proven expertise in oncology, pain.

Brand Name : Undisclosed

Molecule Type : Large molecule

Upfront Cash : Undisclosed

December 18, 2024

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Details:

Orion will continue to developtwo bispecific antibodies, which are currently in late-stage pre-clinical development, successfully developed using Alligator’s RUBY bispecific format.


Lead Product(s): Bispecific Antibody

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: PreclinicalProduct Type: Large molecule

Recipient: Alligator Bioscience

Deal Size: $3.6 million Upfront Cash: Undisclosed

Deal Type: Collaboration November 19, 2024

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Details : Orion will continue to developtwo bispecific antibodies, which are currently in late-stage pre-clinical development, successfully developed using Alligator’s RUBY bispecific format.

Brand Name : Undisclosed

Molecule Type : Large molecule

Upfront Cash : Undisclosed

November 19, 2024

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Details:

ODM-111 is NaV. 1.8 blocker was being evaluated in the early-stage clinical trial studies with the patients for the treatment of acute and chronic pain.


Lead Product(s): ODM-111

Therapeutic Area: Neurology Brand Name: ODM-111

Study Phase: Phase IProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 24, 2024

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Not Confirmed

Lead Product(s) : ODM-111

Therapeutic Area : Neurology

Highest Development Status : Phase I

Partner/Sponsor/Collaborator : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

Details : ODM-111 is NaV. 1.8 blocker was being evaluated in the early-stage clinical trial studies with the patients for the treatment of acute and chronic pain.

Brand Name : ODM-111

Molecule Type : Small molecule

Upfront Cash : Not Applicable

October 24, 2024

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Details:

Nubeqa (darolutamide) is an orally available androgen receptor inhibitors, which is currently being evaluated for the treatment of metastatic hormone-sensitive prostate cancer.


Lead Product(s): Darolutamide,Androgen Deprivation Therapy

Therapeutic Area: Oncology Brand Name: Nubeqa

Study Phase: Phase IIIProduct Type: Small molecule

Recipient: Bayer AG

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 14, 2024

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VMX
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Details : Nubeqa (darolutamide) is an orally available androgen receptor inhibitors, which is currently being evaluated for the treatment of metastatic hormone-sensitive prostate cancer.

Brand Name : Nubeqa

Molecule Type : Small molecule

Upfront Cash : Not Applicable

October 14, 2024

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Details:

Nubeqa (darolutamide) is an orally available androgen receptor inhibitors, which is currently being evaluated in combination with ADT for metastatic hormone-sensitive prostate cancer.


Lead Product(s): Darolutamide,Androgen Deprivation-based Therapy

Therapeutic Area: Oncology Brand Name: Nubeqa

Study Phase: Phase IIIProduct Type: Small molecule

Recipient: Bayer AG

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 26, 2024

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05

VMX
Not Confirmed

Details : Nubeqa (darolutamide) is an orally available androgen receptor inhibitors, which is currently being evaluated in combination with ADT for metastatic hormone-sensitive prostate cancer.

Brand Name : Nubeqa

Molecule Type : Small molecule

Upfront Cash : Not Applicable

September 26, 2024

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Details:

Through the collaboration, Orion and Aitia will work together to discover and validate novel drug targets and to develop drug candidates across multiple oncologic indications.


Lead Product(s): Undisclosed

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Discovery PlatformProduct Type: Undisclosed

Recipient: Aitia

Deal Size: $10.0 million Upfront Cash: Undisclosed

Deal Type: Collaboration September 25, 2024

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06

VMX
Not Confirmed

Details : Through the collaboration, Orion and Aitia will work together to discover and validate novel drug targets and to develop drug candidates across multiple oncologic indications.

Brand Name : Undisclosed

Molecule Type : Undisclosed

Upfront Cash : Undisclosed

September 25, 2024

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Details:

Through the license agreement, Merck will gain global rights to develop and commercialize MK-5684 (opevesostat), which is being evaluated for metastatic castration-resistant prostate cancer.


Lead Product(s): Opevesostat,Dexamethasone,Fludrocortisone Acetate

Therapeutic Area: Oncology Brand Name: MK-5684

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Merck & Co

Deal Size: $1,920.0 million Upfront Cash: $290.0 million

Deal Type: Licensing Agreement July 01, 2024

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VMX
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Details : Through the license agreement, Merck will gain global rights to develop and commercialize MK-5684 (opevesostat), which is being evaluated for metastatic castration-resistant prostate cancer.

Brand Name : MK-5684

Molecule Type : Small molecule

Upfront Cash : $290.0 million

July 01, 2024

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Details:

Under the license agreement, Tenax will be developing and commercializing the TNX-103 (levosimendan) for the treatment of pulmonary hypertension with heart failure with preserved ejection fraction.


Lead Product(s): Levosimendan

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: TNX-103

Study Phase: Phase IIIProduct Type: Small molecule

Recipient: Tenax Therapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement February 20, 2024

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08

VMX
Not Confirmed

Details : Under the license agreement, Tenax will be developing and commercializing the TNX-103 (levosimendan) for the treatment of pulmonary hypertension with heart failure with preserved ejection fraction.

Brand Name : TNX-103

Molecule Type : Small molecule

Upfront Cash : Undisclosed

February 20, 2024

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Details:

The net proceeds will be used to advance Lego's ADC pipeline including, LCB14, an antibody-drug conjugate (ADC) targeting human epidermal growth factor receptor 2 (HER2).


Lead Product(s): LCB14

Therapeutic Area: Oncology Brand Name: LCB14

Study Phase: Phase IIIProduct Type: Large molecule

Recipient: LegoChem Biosciences

Deal Size: $410.9 million Upfront Cash: Undisclosed

Deal Type: Financing January 16, 2024

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09

VMX
Not Confirmed

Details : The net proceeds will be used to advance Lego's ADC pipeline including, LCB14, an antibody-drug conjugate (ADC) targeting human epidermal growth factor receptor 2 (HER2).

Brand Name : LCB14

Molecule Type : Large molecule

Upfront Cash : Undisclosed

January 16, 2024

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Details:

Under the agreement, Orion gains access to Glykos’ ADC technologies, initiating an ADC program and will be responsible for the target selection and commercialization of next-generation ADCs.


Lead Product(s): Undisclosed

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Discovery PlatformProduct Type: Large molecule

Recipient: Glykos

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement January 08, 2024

Fermion Orion Company Banner

10

VMX
Not Confirmed

Details : Under the agreement, Orion gains access to Glykos’ ADC technologies, initiating an ADC program and will be responsible for the target selection and commercialization of next-generation ADCs.

Brand Name : Undisclosed

Molecule Type : Large molecule

Upfront Cash : Undisclosed

January 08, 2024

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