15 Jan 2025
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15 Jan 2025
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13 Jan 2025
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15 Jan 2025
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https://www.orion.fi/en/newsroom/all-news/releases/stock-releases/2024/inside-information-orion-upgrades-full-year-outlook-for-2024/
15 Jan 2025
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https://www.orion.fi/en/newsroom/all-news/releases/stock-releases/2025/recommendation-by-the-orion-nomination-committee-on-the-proposals-to-be-submitted-to-the-2025-annual-general-meeting/
13 Jan 2025
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https://www.orion.fi/en/newsroom/all-news/releases/stock-releases/2025/79345-orion-corporation-a-shares-converted-into-b-shares/#:~:text=In%20accordance%20with%20Section%203,Register%20on%2013%20January%202025.
08 Jan 2025
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https://www.orion.fi/en/newsroom/all-news/releases/press-releases/2025/orions-collaboration-partner-bayer-submits-application-in-china-for-third-indication-of-darolutamide/
02 Jan 2025
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https://www.orion.fi/en/newsroom/all-news/releases/press-releases/2024/orion-and-marinus-terminate-agreement-for-ganaxolone-in-europe/
30 Dec 2024
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https://www.orion.fi/en/newsroom/all-news/releases/press-releases/2024/orion-and-marinus-terminate-agreement-for-ganaxolone-in-europe/
Details:
The collaboration combines Abilita's strength in discovering breakthrough antibody therapeutics for challenging membrane protein targets with Orion's proven expertise in oncology, pain.
Lead Product(s): Antibody
Therapeutic Area: Oncology Brand Name: Undisclosed
Study Phase: DiscoveryProduct Type: Large molecule
Recipient: Abilita Therapeutics
Deal Size: $785.0 million Upfront Cash: Undisclosed
Deal Type: Collaboration December 18, 2024
Lead Product(s) : Antibody
Therapeutic Area : Oncology
Highest Development Status : Discovery
Recipient : Abilita Therapeutics
Deal Size : $785.0 million
Deal Type : Collaboration
Orion, Abilita Collaborate on Antibody Therapeutics With Licensing Options
Details : The collaboration combines Abilita's strength in discovering breakthrough antibody therapeutics for challenging membrane protein targets with Orion's proven expertise in oncology, pain.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
December 18, 2024
Details:
Orion will continue to developtwo bispecific antibodies, which are currently in late-stage pre-clinical development, successfully developed using Alligator’s RUBY bispecific format.
Lead Product(s): Bispecific Antibody
Therapeutic Area: Oncology Brand Name: Undisclosed
Study Phase: PreclinicalProduct Type: Large molecule
Recipient: Alligator Bioscience
Deal Size: $3.6 million Upfront Cash: Undisclosed
Deal Type: Collaboration November 19, 2024
Lead Product(s) : Bispecific Antibody
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Alligator Bioscience
Deal Size : $3.6 million
Deal Type : Collaboration
Orion and Alligator Bioscience Amend their Agreement Concerning Two Bispecific Antibodies
Details : Orion will continue to developtwo bispecific antibodies, which are currently in late-stage pre-clinical development, successfully developed using Alligator’s RUBY bispecific format.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
November 19, 2024
Details:
ODM-111 is NaV. 1.8 blocker was being evaluated in the early-stage clinical trial studies with the patients for the treatment of acute and chronic pain.
Lead Product(s): ODM-111
Therapeutic Area: Neurology Brand Name: ODM-111
Study Phase: Phase IProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable October 24, 2024
Orion Terminates ODM-111 Program Due To Narrow Therapeutic Window Challenges
Details : ODM-111 is NaV. 1.8 blocker was being evaluated in the early-stage clinical trial studies with the patients for the treatment of acute and chronic pain.
Brand Name : ODM-111
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 24, 2024
Details:
Nubeqa (darolutamide) is an orally available androgen receptor inhibitors, which is currently being evaluated for the treatment of metastatic hormone-sensitive prostate cancer.
Lead Product(s): Darolutamide,Androgen Deprivation Therapy
Therapeutic Area: Oncology Brand Name: Nubeqa
Study Phase: Phase IIIProduct Type: Small molecule
Recipient: Bayer AG
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable October 14, 2024
Lead Product(s) : Darolutamide,Androgen Deprivation Therapy
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : Bayer AG
Deal Size : Not Applicable
Deal Type : Not Applicable
Bayer Submits Third EU Indication Application for Darolutamide via Orion Collaboration
Details : Nubeqa (darolutamide) is an orally available androgen receptor inhibitors, which is currently being evaluated for the treatment of metastatic hormone-sensitive prostate cancer.
Brand Name : Nubeqa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 14, 2024
Details:
Nubeqa (darolutamide) is an orally available androgen receptor inhibitors, which is currently being evaluated in combination with ADT for metastatic hormone-sensitive prostate cancer.
Lead Product(s): Darolutamide,Androgen Deprivation-based Therapy
Therapeutic Area: Oncology Brand Name: Nubeqa
Study Phase: Phase IIIProduct Type: Small molecule
Recipient: Bayer AG
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable September 26, 2024
Lead Product(s) : Darolutamide,Androgen Deprivation-based Therapy
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : Bayer AG
Deal Size : Not Applicable
Deal Type : Not Applicable
Bayer Submits FDA Application For Third Indication of Darolutamide
Details : Nubeqa (darolutamide) is an orally available androgen receptor inhibitors, which is currently being evaluated in combination with ADT for metastatic hormone-sensitive prostate cancer.
Brand Name : Nubeqa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 26, 2024
Details:
Through the collaboration, Orion and Aitia will work together to discover and validate novel drug targets and to develop drug candidates across multiple oncologic indications.
Lead Product(s): Undisclosed
Therapeutic Area: Oncology Brand Name: Undisclosed
Study Phase: Discovery PlatformProduct Type: Undisclosed
Recipient: Aitia
Deal Size: $10.0 million Upfront Cash: Undisclosed
Deal Type: Collaboration September 25, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Recipient : Aitia
Deal Size : $10.0 million
Deal Type : Collaboration
Orion, Aitia Partner on AI-Driven Drug Discovery and Simulation in Oncology
Details : Through the collaboration, Orion and Aitia will work together to discover and validate novel drug targets and to develop drug candidates across multiple oncologic indications.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
September 25, 2024
Details:
Through the license agreement, Merck will gain global rights to develop and commercialize MK-5684 (opevesostat), which is being evaluated for metastatic castration-resistant prostate cancer.
Lead Product(s): Opevesostat,Dexamethasone,Fludrocortisone Acetate
Therapeutic Area: Oncology Brand Name: MK-5684
Study Phase: Phase IIIProduct Type: Small molecule
Sponsor: Merck & Co
Deal Size: $1,920.0 million Upfront Cash: $290.0 million
Deal Type: Licensing Agreement July 01, 2024
Lead Product(s) : Opevesostat,Dexamethasone,Fludrocortisone Acetate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Merck & Co
Deal Size : $1,920.0 million
Deal Type : Licensing Agreement
Merck and Orion Mutual Option Exercise for Opevesostat in Prostate Cancer Treatment
Details : Through the license agreement, Merck will gain global rights to develop and commercialize MK-5684 (opevesostat), which is being evaluated for metastatic castration-resistant prostate cancer.
Brand Name : MK-5684
Molecule Type : Small molecule
Upfront Cash : $290.0 million
July 01, 2024
Details:
Under the license agreement, Tenax will be developing and commercializing the TNX-103 (levosimendan) for the treatment of pulmonary hypertension with heart failure with preserved ejection fraction.
Lead Product(s): Levosimendan
Therapeutic Area: Cardiology/Vascular Diseases Brand Name: TNX-103
Study Phase: Phase IIIProduct Type: Small molecule
Recipient: Tenax Therapeutics
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Licensing Agreement February 20, 2024
Lead Product(s) : Levosimendan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Recipient : Tenax Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Tevogen Bio Prepares to Launch Genetic Predisposition Study for TVGN 489 in Long COVID
Details : Under the license agreement, Tenax will be developing and commercializing the TNX-103 (levosimendan) for the treatment of pulmonary hypertension with heart failure with preserved ejection fraction.
Brand Name : TNX-103
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 20, 2024
Details:
The net proceeds will be used to advance Lego's ADC pipeline including, LCB14, an antibody-drug conjugate (ADC) targeting human epidermal growth factor receptor 2 (HER2).
Lead Product(s): LCB14
Therapeutic Area: Oncology Brand Name: LCB14
Study Phase: Phase IIIProduct Type: Large molecule
Recipient: LegoChem Biosciences
Deal Size: $410.9 million Upfront Cash: Undisclosed
Deal Type: Financing January 16, 2024
Lead Product(s) : LCB14
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : LegoChem Biosciences
Deal Size : $410.9 million
Deal Type : Financing
LegoChemBio Joins Hands with Orion to Become a Global Top ADC Company
Details : The net proceeds will be used to advance Lego's ADC pipeline including, LCB14, an antibody-drug conjugate (ADC) targeting human epidermal growth factor receptor 2 (HER2).
Brand Name : LCB14
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 16, 2024
Details:
Under the agreement, Orion gains access to Glykos’ ADC technologies, initiating an ADC program and will be responsible for the target selection and commercialization of next-generation ADCs.
Lead Product(s): Undisclosed
Therapeutic Area: Oncology Brand Name: Undisclosed
Study Phase: Discovery PlatformProduct Type: Large molecule
Recipient: Glykos
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Licensing Agreement January 08, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Recipient : Glykos
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Orion and Glykos Announce Research Collaboration for Next-Generation Adcs
Details : Under the agreement, Orion gains access to Glykos’ ADC technologies, initiating an ADC program and will be responsible for the target selection and commercialization of next-generation ADCs.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 08, 2024
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