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Under the terms of the agreement, Pyramid Biosciences will develop and commercialize GQ1010, a potential best-in-class antibody drug conjugate (ADC) targeting TROP2, worldwide except for Greater China, using GeneQuantum's proprietary technology.


Lead Product(s): GQ1010

Therapeutic Area: Oncology Product Name: GQ1010

Highest Development Status: IND EnablingProduct Type: Large molecule

Partner/Sponsor/Collaborator: GeneQuantum Healthcare

Deal Size: $1,020.0 million Upfront Cash: $20.0 million

Deal Type: Licensing Agreement April 13, 2023

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PBI-200 is an oral, highly potent, and selective inhibitor of TRK kinase that is currently in clinical development for the treatment of patients with cancers that harbor abnormalities involving the tropomyosin receptor kinases.


Lead Product(s): PBI-200

Therapeutic Area: Oncology Product Name: PBI-200

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 06, 2022

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Molecular Intelligence Trials (MI Trials) collaboration will enhance identification of patients with NTRK fusion-positive solid tumors, including primary and metastatic CNS tumors potentially eligible for enrollment in the ongoing PBI-200-101 Phase 1/2 clinical study.


Lead Product(s): PBI-200

Therapeutic Area: Oncology Product Name: PBI-200

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Caris Life Sciences

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration March 10, 2022

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