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1. 7440-36-0
2. Sb
3. Stibium Metallicum
4. Antimony, Ion (sb(3-))
5. Antimoine
6. Antimonio
7. Antimony Ingot
8. Mfcd00011211
9. Mfcd00134030
10. Antimony, Metallic
11. Antimony, Elemental
12. Antymonowodor [polish]
13. Antimonide
14. Antymonowodor
15. Antimon
16. Antimonwasserstoffes [german]
17. Antimony Atom
18. Hsdb 785
19. Antimony(0)
20. Antimonwasserstoffes
21. Antimony Single Crystal Disc, 10mm (0.39in) Dia, 1-3mm (0.04-0.1in) Thick, (100) Orientation
22. Un2676
23. 51sb
24. Unii-0vkz97k3ub
25. Sb(0)
26. Antimony, P.a., 99.0%
27. Chebi:30304
28. Chebi:30513
29. Dtxsid10872432
30. Dtxsid601014341
31. Stibine [un2676] [poison Gas]
32. Akos015833653
33. Akos028110012
34. Db13110
35. Ft-0622427
36. Q1099
37. Antimony, Rod, 6mm, Diameter 6mm, 99.999%
38. Antimony, Rod, 15mm, Diameter 2.0mm, 99.99%
39. Antimony, Rod, 25mm, Diameter 2.0mm, 99.99%
40. Antimony, Rod, 50mm, Diameter 2.0mm, 99.99%
41. Antimony, Rod, 20mm, Diameter 4.7mm, 99.999%
42. Antimony, Rod, 25mm, Diameter 4.7mm, 99.999%
43. Antimony, Rod, 50mm, Diameter 4.7mm, 99.999%
44. Antimony, Foil, 50x50mm, Thickness 2mm, Hot-pressed
45. Antimony, Beads, 1-2 Mm, 99.999% Trace Metals Basis
46. Antimony Ingot, 99.9999% (6n) Ingots With Approx. 2 Kg
47. Antimony, Powder, -100 Mesh, 99.5% Trace Metals Basis
48. Antimony, Oil Based Standard Solution, Specpure, Sb 1000g/g
49. Antimony, Oil Based Standard Solution, Specpure, Sb 5000g/g
50. Antimony, Plasma Standard Solution, Specpure?, Sb 1000?g/ml
51. Antimony Implanted In Silicon, Erm(r) Certified Reference Material
52. Antimony, Beads, 1-5 Mm, Low Oxide, 99.999% Trace Metals Basis
53. Antimony, Plasma Standard Solution, Specpure?, Sb 10,000?g/ml
54. Antimony, Foil, Thickness 0.004 Mm, Size 25 X 25 Mm, Purity 95+%
55. Antimony, Foil, Thickness 0.006 Mm, Size 25 X 25 Mm, Purity 95+%
56. Antimony, Foil, Thickness 0.006 Mm, Size 50 X 50 Mm, Purity 95+%
57. Antimony, Foil, Thickness 0.007 Mm, Size 25 X 25 Mm, Purity 95+%
58. Antimony, Foil, Thickness 0.008 Mm, Size 25 X 25 Mm, Purity 95+%
59. Antimony, Foil, Thickness 0.009 Mm, Size 25 X 25 Mm, Purity 95+%
60. Antimony, Foil, Thickness 0.0125 Mm, Size 50 X 50 Mm, Purity 95+%
61. Antimony, Foil, Thickness 0.02 Mm, Size 22 X 25 Mm, Purity 95+%
62. Antimony, Foil, Thickness 0.02 Mm, Size 50 X 50 Mm, Purity 95+%
63. Antimony, Foil, Thickness 0.04 Mm, Size 25 X 25 Mm, Purity 95+%
64. Antimony, Foil, Thickness 0.04 Mm, Size 50 X 50 Mm, Purity 95+%
65. Antimony, Lump, 20 Mm Max. Lump Size, Weight 100 G, High Purity 99.999%
66. Antimony, Lump, 20 Mm Max. Lump Size, Weight 20 G, High Purity 99.999%
67. Antimony, Lump, 20 Mm Max. Lump Size, Weight 50 G, High Purity 99.999%
68. Antimony, Lump, 4 Mm Max. Lump Size, Weight 100 G, Purity 99.5+%
69. Antimony, Lump, 4 Mm Max. Lump Size, Weight 1000 G, Purity 99.5+%
70. Antimony, Lump, 4 Mm Max. Lump Size, Weight 200 G, Purity 99.5+%
71. Antimony, Lump, 4 Mm Max. Lump Size, Weight 2000 G, Purity 99.5+%
72. Antimony, Lump, 4 Mm Max. Lump Size, Weight 500 G, Purity 99.5+%
73. Antimony, Lump, 5 Mm Max. Lump Size, Weight 100 G, High Purity 99.9999%
74. Antimony, Lump, 5 Mm Max. Lump Size, Weight 20 G, High Purity 99.9999%
75. Antimony, Lump, 5 Mm Max. Lump Size, Weight 50 G, High Purity 99.9999%
76. Antimony Standard Solution, 1000 Ppm Sb, Suitable For Atomic Absorption Spectrometry
77. Antimony, Powder, 150 Max. Part. Size (micron), Weight 100 G, High Purity 99.999%
78. Antimony, Powder, 150 Max. Part. Size (micron), Weight 1000 G, Purity 99.2%
79. Antimony, Powder, 150 Max. Part. Size (micron), Weight 200 G, High Purity 99.999%
80. Antimony, Powder, 150 Max. Part. Size (micron), Weight 200 G, Purity 99.2%
81. Antimony, Powder, 150 Max. Part. Size (micron), Weight 50 G, High Purity 99.999%
82. Antimony, Powder, 150 Max. Part. Size (micron), Weight 50 G, Purity 99.2%
83. Antimony, Powder, 150 Max. Part. Size (micron), Weight 500 G, Purity 99.2%
84. Antimony, Powder, 45 Max. Part. Size (micron), Weight 100 G, Purity 99.5+%
85. Antimony, Powder, 45 Max. Part. Size (micron), Weight 20 G, Purity 99.5+%
86. Antimony, Powder, 45 Max. Part. Size (micron), Weight 50 G, Purity 99.5+%
87. Antimony, Powder, 75 Max. Part. Size (micron), Weight 200 G, Purity 99.2%
88. Antimony, Powder, 75 Max. Part. Size (micron), Weight 50 G, Purity 99.2%
89. Antimony, Powder, Max. Particle Size 150 Micron, Weight 100 G, Purity 99.2%
90. Antimony, Powder, Max. Particle Size 150 Micron, Weight 20 G, High Purity 99.999%
91. Antimony, Powder, Max. Particle Size 45 Micron, Weight 200 G, Purity 99.5+%
92. Antimony, Powder, Max. Particle Size 75 Micron, Weight 100 G, Purity 99.2%
93. Antimony Atomic Spectroscopy Standard Concentrate 10.00 G Sb, 10.00 G/l, For 1l Standard Solution, Analytical Standard
94. Antimony, Foil, Light Tested, 25x25mm, Thickness 0.05mm, Permanent Polyester Support, 95+%
95. Antimony, Foil, Light Tested, 50x50mm, Thickness 0.05mm, Permanent Polyester Support, 95+%
96. Antimony, Foil, Not Light Tested, 100x100mm, Thickness 0.015mm, Permanent Polyester Support, 95+%
97. Antimony, Foil, Not Light Tested, 100x100mm, Thickness 0.01mm, Permanent Polyester Support, 95+%
98. Antimony, Foil, Not Light Tested, 100x100mm, Thickness 0.025mm, Permanent Polyester Support, 95+%
99. Antimony, Foil, Not Light Tested, 100x100mm, Thickness 0.05mm, Permanent Polyester Support, 95+%
100. Antimony, Foil, Not Light Tested, 25x25mm, Thickness 0.002mm, Permanent Polyester Support, 95+%
101. Antimony, Foil, Not Light Tested, 25x25mm, Thickness 0.005mm, Permanent Polyester Support, 95+%
102. Antimony, Foil, Not Light Tested, 25x25mm, Thickness 0.015mm, Permanent Polyester Support, 95+%
103. Antimony, Foil, Not Light Tested, 25x25mm, Thickness 0.01mm, Permanent Polyester Support, 95+%
104. Antimony, Foil, Not Light Tested, 25x25mm, Thickness 0.025mm, Permanent Polyester Support, 95+%
105. Antimony, Foil, Not Light Tested, 50x50mm, Thickness 0.002mm, Permanent Polyester Support, 95+%
106. Antimony, Foil, Not Light Tested, 50x50mm, Thickness 0.005mm, Permanent Polyester Support, 95+%
107. Antimony, Foil, Not Light Tested, 50x50mm, Thickness 0.015mm, Permanent Polyester Support, 95+%
108. Antimony, Foil, Not Light Tested, 50x50mm, Thickness 0.01mm, Permanent Polyester Support, 95+%
109. Antimony, Foil, Not Light Tested, 50x50mm, Thickness 0.025mm, Permanent Polyester Support, 95+%
110. Antimony, Foil, Not Light Tested, 50x50mm, Thickness 0.05mm, Permanent Polyester Support, 95+%
111. Antimony, Microfoil, 25x25mm, Thinness 0.5mum, Specific Density 334.5mug/cm2, 6 Micron Aluminum Permanent Support, 95+%
112. Antimony, Microfoil, 50x50mm, Thinness 0.5mum, Specific Density 334.5mug/cm2, 6 Micron Aluminum Permanent Support, 95+%
| Molecular Weight | 121.760 g/mol |
|---|---|
| Molecular Formula | Sb |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 0 |
| Rotatable Bond Count | 0 |
| Exact Mass | 120.90381 g/mol |
| Monoisotopic Mass | 120.90381 g/mol |
| Topological Polar Surface Area | 0 Ų |
| Heavy Atom Count | 1 |
| Formal Charge | 0 |
| Complexity | 0 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Paracelsus, a physician and proponent of alchemy in sixteen century Europe, and his followers favored the use of metals, including antimony, as drugs. The view of the Paracelsus followers diverged from the teachings of Galen (c. AD 13-201), a preeminent Roman physician who considered metals to be poisonous. The period of c. 1560-1660 was termed the 'antimony war' and reflects the conflict in medicine between Galenic medicine and the practices of Paracelsus. /Former use/
Nordberg, G.F. et al; Handbook on the Toxicology of Metals 4th ed., Vol. 2. Academic Press, Waltham, MA. 2015, p. v2 p 566
A study of the retention patterns of labeled antimony in mice following inhalation of particles formed at different temp was conducted. The lower temp aerosol was more sol & left the lung rapidly, localizing in the skeleton. The 2 aerosols produced at higher temp resulted in (124)antimony remaining in the lung for extended periods.
PMID:4746928 THOMAS RG ET AL; PROC SOC EXP BIOL MED 144 (2): 544-50 (1973)
Environment and nutrition influence antimony concentrations of human tissues, causing large differences among individuals. Extremely high levels were found in the lung and bone tissues but not in liver or kidney of deceased antimony smelter workers. The lung contain the highest antimony levels of human tissues. The distribution of antimony is not homogeneous within organs or tissues. ... Great variations of antimony content were found in normal human platelets, serum albumin, and different tissues. /Antimony/
Seiler, H.G., H. Sigel and A. Sigel (eds.). Handbook on the Toxicity of Inorganic Compounds. New York, NY: Marcel Dekker, Inc. 1988., p. 71
Urine levels of antimony between 0.4 and 0.7 mg/L were measured in cases of workers with lung changes. /Antimony/
Seiler, H.G., H. Sigel and A. Sigel (eds.). Handbook on the Toxicity of Inorganic Compounds. New York, NY: Marcel Dekker, Inc. 1988., p. 71
Arsenic and antimony are toxic metalloids, naturally present in the environment and all organisms have developed pathways for their detoxification. The most effective metalloid tolerance systems in eukaryotes include downregulation of metalloid uptake, efflux out of the cell, and complexation with phytochelatin or glutathione followed by sequestration into the vacuole. Understanding of arsenic and antimony transport system is of high importance due to the increasing usage of arsenic-based drugs in the treatment of certain types of cancer and diseases caused by protozoan parasites as well as for the development of bio- and phytoremediation strategies for metalloid polluted areas. However, in contrast to prokaryotes, the knowledge about specific transporters of arsenic and antimony and the mechanisms of metalloid transport in eukaryotes has been very limited for a long time. Here, we review the recent advances in understanding of arsenic and antimony transport pathways in eukaryotes, including a dual role of aquaglyceroporins in uptake and efflux of metalloids, elucidation of arsenic transport mechanism by the yeast Acr3 transporter and its role in arsenic hyperaccumulation in ferns, identification of vacuolar transporters of arsenic-phytochelatin complexes in plants and forms of arsenic substrates recognized by mammalian ABC transporters. /Antimony/
PMID:22489166 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317726 Maciaszczyk-Dziubinska E et al; Int J Mol Sci 13 (3): 3527-48 (2012)
For more Absorption, Distribution and Excretion (Complete) data for Antimony, elemental (13 total), please visit the HSDB record page.
Recently, tellurium (Te), antimony (Sb) and germanium (Ge) have been used as an alloy in phase-change optical magnetic disks, such as digital versatile disk-random access memory (DVD-RAM) and DVD-recordable disk (DVD-RW). Although these metalloids, the so-called "exotic" elements, are known to be non-essential and harmful, little is known about their toxic effects and metabolism. Metalloid compounds, tellurite, antimonite and germanium dioxide, were simultaneously administered to rats. Their distributions metabolites were determined and identified by speciation. Te and Sb accumulated in red blood cells (RBCs): Te accumulated in RBCs in the dimethylated form, while Sb accumulated in the inorganic/non-methylated form. In addition, trimethyltelluronium (TMTe) was the urinary metabolite of Te, whereas Sb in urine was not methylated but oxidized. Ge was also not methylated in rats. These results suggest that each metalloid is metabolized via a unique pathway. /Antimony metabolites/
PMID:19483383 Kobayashi A, Ogra Y; J Toxicol Sci 34 (3): 295-303 (2009)
Whole body: 76 hours; The pentavalent form is removed faster than trivalent form. [TDR, p. 109]
TDR - Ryan RP, Terry CE, Leffingwell SS (eds). Toxicology Desk Reference: The Toxic Exposure and Medical Monitoring Index, 5th Ed. Washington DC: Taylor & Francis, 1999., p. 109
Airborne factory dust (with a volume median diameter of 5.0 um and a geometric standard deviation of 2.1 um) from a Swedish copper smeltery contained antimony (1.6 weight %) and arsenic (19 weight %). The dust was neutron activated and intratracheally instilled in hamsters. In vivo measurements of lung clearance were undertaken of the radionuclides (76)arsenic, (122)antimony, and (124)antimony. Two phases were recognized in the clearance curves. The approx half-time for the initial phase was about 40 hr for antimony trioxide, and 30 hr for antimony dust. The second phase had an approx half-time of 20-40 days for antimony trioxide and antimony dust. The low solubility of antimony in factory dust combined with a long biological half-time may be of importance in explaining the observed lung accumulation of antimony in exposed workers.
PMID:6541805 Leffler P et al; Scand J Work Environ Health 10 (4): 245-51 (1984)
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A Antimony manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Antimony, including repackagers and relabelers. The FDA regulates Antimony manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Antimony API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Antimony supplier is an individual or a company that provides Antimony active pharmaceutical ingredient (API) or Antimony finished formulations upon request. The Antimony suppliers may include Antimony API manufacturers, exporters, distributors and traders.
Antimony Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Antimony GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Antimony GMP manufacturer or Antimony GMP API supplier for your needs.
A Antimony CoA (Certificate of Analysis) is a formal document that attests to Antimony's compliance with Antimony specifications and serves as a tool for batch-level quality control.
Antimony CoA mostly includes findings from lab analyses of a specific batch. For each Antimony CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Antimony may be tested according to a variety of international standards, such as European Pharmacopoeia (Antimony EP), Antimony JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Antimony USP).
