Find Sodium Dithionite manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

API REF. PRICE (USD/KG)

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Regulatory FDF Prices

NA

API/FDF Prices: Book a Demo to
explore the features and consider
upgrading later

MARKET PLACE

0

API

0

FDF

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Sodium hydrosulfite, 7775-14-6, Sodium hydrosulphite, Dithionous acid, disodium salt, Sodium sulfoxylate, Disodium dithionite
Molecular Formula
Na2O4S2
Molecular Weight
174.11  g/mol
InChI Key
JVBXVOWTABLYPX-UHFFFAOYSA-L
FDA UNII
2K5B8F6ES1

Sodium Dithionite
Dithionite. The dithionous acid ion and its salts.
1 2D Structure

Sodium Dithionite

2 Identification
2.1 Computed Descriptors
2.1.1 InChI
InChI=1S/2Na.H2O4S2/c;;1-5(2)6(3)4/h;;(H,1,2)(H,3,4)/q2*+1;/p-2
2.1.2 InChI Key
JVBXVOWTABLYPX-UHFFFAOYSA-L
2.1.3 Canonical SMILES
[O-]S(=O)S(=O)[O-].[Na+].[Na+]
2.2 Other Identifiers
2.2.1 UNII
2K5B8F6ES1
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Dithionite

2. Dithionite, Sodium

3. Hyposulfite

2.3.2 Depositor-Supplied Synonyms

1. Sodium Hydrosulfite

2. 7775-14-6

3. Sodium Hydrosulphite

4. Dithionous Acid, Disodium Salt

5. Sodium Sulfoxylate

6. Disodium Dithionite

7. Sodium Hypodisulfite

8. Vatrolite

9. 2k5b8f6es1

10. Chebi:66870

11. Blankit

12. Burmol

13. Hydros

14. Sodiumdithionite

15. Blankit In

16. Hydrosulfite R Conc

17. V-brite B

18. Disodium Hydrosulfite

19. Caswell No. 774

20. Ccris 1428

21. Hsdb 746

22. Sodium Hydrosulfite (na2s2o4)

23. Sodium Dithionite (na2(s2o4))

24. Einecs 231-890-0

25. Un1384

26. Epa Pesticide Chemical Code 078202

27. Unii-2k5b8f6es1

28. Sodium Dithionit

29. Sodiumhydrosulfite

30. Sodiumhydrosulphite

31. Sodium Hydro Sulfite

32. Mfcd00011640

33. Sodium Sodium Hydrosulfite

34. Dithionous Aciddisodiumsalt

35. Na2s2o4

36. Ec 231-890-0

37. Sodium Dithionite (na2s2o4)

38. Sodium Dithionite [ii]

39. Sodium Dithionite [mi]

40. Chembl3410462

41. Dtxsid9029697

42. Na2 (s2 O4)

43. Sodium Dithionite [mart.]

44. Sodium Hydrosulfite [hsdb]

45. Sodium Hydrosulfite [inci]

46. Dithionous Acid, Sodium Salt (1:2)

47. Akos015904498

48. Sodium Dithionite Or Sodium Hydrosulfite

49. Bp-13393

50. Ft-0695294

51. S0562

52. Q414560

53. Sodium Dithionite Or Sodium Hydrosulfite [un1384] [spontaneously Combustible]

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 174.11 g/mol
Molecular Formula Na2O4S2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count0
Exact Mass173.90333939 g/mol
Monoisotopic Mass173.90333939 g/mol
Topological Polar Surface Area119 Ų
Heavy Atom Count8
Formal Charge0
Complexity60.5
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Therapeutic Uses

Sodium thiosulfate is used in humans to lessen some of the side effects of cisplatin (a cancer medicine). It is also used in the emergency treatment of cyanide poisoning. Sodium thiosulfate is assumed to be intrinsically non-toxic.

OECD; SIDS Initial Assessment Reports for Sodium Dithionite (CAS No.: 7775-14-6) for SIAM 19 (October 2004). Available from, as of November 10, 2009: https://www.inchem.org/documents/sids/sids/7775146.pdf


Sulfites such as sodium pyrosulfite and sodium dithionite, applied topically to the skin of cement workers, appear to be effective in prevention of dermatitis. 9 previously proven chrome sensitive individuals were patch tested with aqueous potassium dichromate 0.5 % mixed with sodium dithionite in the proportion of 3 g/L. Not one patient developed a positive reaction to the chromate mixed with sodium dithionite, though all reacted to 0.5 % chromate in water without sodium dithionite.

European Commission, ESIS; IUCLID Dataset, Sodium dithionite (7775-14-6) (April 2006). Available from, as of November 10, 2009: https://esis.jrc.ec.europa.eu/


4.2 Minimum/Potential Fatal Human Dose

Probable oral lethal dose (human) 0.5-5 g/kg bw.

European Commission, ESIS; IUCLID Dataset, Sodium dithionite (7775-14-6) (April 2006). Available from, as of November 10, 2009: https://esis.jrc.ec.europa.eu/


3. 3= MODERATELY TOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) 0.5-5 G/KG, BETWEEN 1 OZ & 1 PINT (OR 1 LB) FOR 70 KG PERSON (150 LB). /SULFITES/

Gosselin, R.E., H.C. Hodge, R.P. Smith, and M.N. Gleason. Clinical Toxicology of Commercial Products. 4th ed. Baltimore: Williams and Wilkins, 1976., p. II-85


5 Pharmacology and Biochemistry
5.1 Metabolism/Metabolites

Sodium dithionite is not stable under physiological conditions, with the rate of decomposition increasing with increasing acidity. Upon contact with moisture, it is oxidized to hydrogen sulfite, sulfite and hydrogen sulfate, and under strongly acidic conditions it may liberate sulfur dioxide. Under anaerobic conditions (such as in the lower gastrointestinal tract), hydrogen sulfite and thiosulfate may be formed. Hydrogen sulfite can be absorbed after ingestion. It is efficiently metabolized, and the major part rapidly excreted as sulfate into the urine.

OECD; SIDS Initial Assessment Reports for Sodium Dithionite (CAS No.: 7775-14-6) for SIAM 19 (October 2004). Available from, as of October 19, 2009: https://www.inchem.org/documents/sids/sids/7775146.pdf


As sodium dithionite is chemically unstable in the presence of water and oxygen, in particular under acidic conditions, rapid conversion of sodium dithionite into various related sulfite species is expected to occur under physiological conditions. Therefore, it is justified to take account of toxicological data of sodium sulfite, sodium hydrogen sulfite, and disodium disulfite (= sodium metabisulfite) in the human health assessment of dithionite ... In this context, sodium sulfite and sodium hydrogen sulfite are considered to be the predominant chemicals that are systemically available to the body.

OECD; SIDS Initial Assessment Reports for Sodium Dithionite (CAS No.: 7775-14-6) for SIAM 19 (October 2004). Available from, as of October 19, 2009: https://www.inchem.org/documents/sids/sids/7775146.pdf


Market Place

Do you need sourcing support? Ask us

ABOUT THIS PAGE

Looking for 7775-14-6 / Sodium Dithionite API manufacturers, exporters & distributors?

Sodium Dithionite manufacturers, exporters & distributors 1

89

PharmaCompass offers a list of Sodium Dithionite API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Sodium Dithionite manufacturer or Sodium Dithionite supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Sodium Dithionite manufacturer or Sodium Dithionite supplier.

PharmaCompass also assists you with knowing the Sodium Dithionite API Price utilized in the formulation of products. Sodium Dithionite API Price is not always fixed or binding as the Sodium Dithionite Price is obtained through a variety of data sources. The Sodium Dithionite Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Sodium Dithionite

Synonyms

Sodium hydrosulfite, 7775-14-6, Sodium hydrosulphite, Dithionous acid, disodium salt, Sodium sulfoxylate, Disodium dithionite

Cas Number

7775-14-6

Unique Ingredient Identifier (UNII)

2K5B8F6ES1

About Sodium Dithionite

Dithionite. The dithionous acid ion and its salts.

Sodium Dithionite Manufacturers

A Sodium Dithionite manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sodium Dithionite, including repackagers and relabelers. The FDA regulates Sodium Dithionite manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sodium Dithionite API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Sodium Dithionite Suppliers

A Sodium Dithionite supplier is an individual or a company that provides Sodium Dithionite active pharmaceutical ingredient (API) or Sodium Dithionite finished formulations upon request. The Sodium Dithionite suppliers may include Sodium Dithionite API manufacturers, exporters, distributors and traders.

Sodium Dithionite GMP

Sodium Dithionite Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sodium Dithionite GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sodium Dithionite GMP manufacturer or Sodium Dithionite GMP API supplier for your needs.

Sodium Dithionite CoA

A Sodium Dithionite CoA (Certificate of Analysis) is a formal document that attests to Sodium Dithionite's compliance with Sodium Dithionite specifications and serves as a tool for batch-level quality control.

Sodium Dithionite CoA mostly includes findings from lab analyses of a specific batch. For each Sodium Dithionite CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sodium Dithionite may be tested according to a variety of international standards, such as European Pharmacopoeia (Sodium Dithionite EP), Sodium Dithionite JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sodium Dithionite USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty