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    2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinane-5-carbonyl)amino]acetic acid

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    $ API Ref.Price (USD/KG) : 30,231Xls

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    2D Structure
    Also known as: 960539-70-2, Gsk1278863, Gsk-1278863, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxopyrimidin-5-yl)carbonyl)glycine, Gsk 1278863, Jvr38zm64b
    Molecular Formula
    C19H27N3O6
    Molecular Weight
    393.4  g/mol
    InChI Key
    RUEYEZADQJCKGV-UHFFFAOYSA-N
    FDA UNII
    JVR38ZM64B
    Daprodustat has been used in trials studying the other, treatment, and basic science of Anaemia, Wound Healing, Tendon Injuries, Surgical Procedures, and Vascular Disease, Peripheral.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinane-5-carbonyl)amino]acetic acid
    2.1.2 InChI
    InChI=1S/C19H27N3O6/c23-14(24)11-20-16(25)15-17(26)21(12-7-3-1-4-8-12)19(28)22(18(15)27)13-9-5-2-6-10-13/h12-13,15H,1-11H2,(H,20,25)(H,23,24)
    2.1.3 InChI Key
    RUEYEZADQJCKGV-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1CCC(CC1)N2C(=O)C(C(=O)N(C2=O)C3CCCCC3)C(=O)NCC(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    JVR38ZM64B
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 2-(1,3-dicyclohexyl-6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamido)acetic Acid

    2. Gsk1278863

    2.3.2 Depositor-Supplied Synonyms

    1. 960539-70-2

    2. Gsk1278863

    3. Gsk-1278863

    4. N-((1,3-dicyclohexylhexahydro-2,4,6-trioxopyrimidin-5-yl)carbonyl)glycine

    5. Gsk 1278863

    6. Jvr38zm64b

    7. 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic Acid

    8. Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)-

    9. Duvroq

    10. (1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carbonyl)glycine

    11. 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinane-5-carbonyl)amino]acetic Acid

    12. Daprodustat [usan:inn]

    13. Unii-jvr38zm64b

    14. Duvroq (tn)

    15. Daprodustat [inn]

    16. Daprodustat [jan]

    17. Daprodustat [usan]

    18. Daprodustat [who-dd]

    19. Daprodustat; Gsk1278863

    20. Daprodustat (jan/usan/inn)

    21. Gtpl8455

    22. Daprodustat (gsk1278863)

    23. Chembl3544988

    24. Schembl21725048

    25. Dtxsid501337360

    26. Amy27907

    27. Bcp16766

    28. Ex-a1121

    29. Mfcd29924726

    30. S8171

    31. Akos027439964

    32. Zinc231226004

    33. Ccg-268574

    34. Cs-5453

    35. Db11682

    36. Sb19761

    37. Ac-30915

    38. Bg166670

    39. Hy-17608

    40. Db-096637

    41. J3.560.573h

    42. D10874

    43. A902761

    44. Q27076986

    45. Daprodustat;(1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carbonyl)glycine

    2.4 Create Date
    2015-03-18
    3 Chemical and Physical Properties
    Molecular Weight 393.4 g/mol
    Molecular Formula C19H27N3O6
    XLogP32.5
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count5
    Exact Mass393.18998559 g/mol
    Monoisotopic Mass393.18998559 g/mol
    Topological Polar Surface Area124 Ų
    Heavy Atom Count28
    Formal Charge0
    Complexity627
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Indication

    Treatment of anaemia due to chronic disorders

    5 Pharmacology and Biochemistry
    5.1 ATC Code

    B - Blood and blood forming organs

    B03 - Antianemic preparations

    B03X - Other antianemic preparations

    B03XA - Other antianemic preparations

    B03XA07 - Daprodustat