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    CAS 29331-92-8

    BUILDING BLOCK

    PharmaCompass
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    2D Structure
    Also known as: 29331-92-8, 10-hydroxy-10,11-dihydro-5h-dibenzo[b,f]azepine-5-carboxamide, 10-hydroxycarbazepine, 10,11-dihydro-10-hydroxycarbamazepine, 10-hydroxycarbamazepine, 10-oh-carbazepine
    Molecular Formula
    C15H14N2O2
    Molecular Weight
    254.28  g/mol
    InChI Key
    BMPDWHIDQYTSHX-UHFFFAOYSA-N
    FDA UNII
    XFX1A5KJ3V
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    5-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide
    2.1.2 InChI
    InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)
    2.1.3 InChI Key
    BMPDWHIDQYTSHX-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1C(C2=CC=CC=C2N(C3=CC=CC=C31)C(=O)N)O
    2.2 Other Identifiers
    2.2.1 UNII
    XFX1A5KJ3V
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 10,11-dihydro-10-hydroxy-5h-dibenz(b,f)azepine-5-carboxamide

    2. 10,11-mhd

    2.3.2 Depositor-Supplied Synonyms

    1. 29331-92-8

    2. 10-hydroxy-10,11-dihydro-5h-dibenzo[b,f]azepine-5-carboxamide

    3. 10-hydroxycarbazepine

    4. 10,11-dihydro-10-hydroxycarbamazepine

    5. 10-hydroxycarbamazepine

    6. 10-oh-carbazepine

    7. Gp 47779

    8. 10-hydroxy-10,11-dihydrocarbamazepine

    9. 10,11-dihydro-10-hydroxycarbazepine

    10. Gp-47779

    11. 10,11-dihydro-10-hydroxy Carbamazepine

    12. Licarbazepine [inn]

    13. 10-hydroxy-carbamazepine

    14. 5-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide

    15. 10,11-dihydro-10-hydroxy-5h-dibenz(b,f)azepine-5-carboxamide

    16. 5h-dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-

    17. Xfx1a5kj3v

    18. Chembl1067

    19. Chebi:701

    20. S-licarbazepine

    21. 10,11-dihydro-10-hydroxy-5h-dibenz[b,f]azepine-5-carboxamide

    22. 5h-dibenz(b,f)azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-

    23. Unii-xfx1a5kj3v

    24. Bia 2-005

    25. 10-hydroxy-10,11-dihydro-5h-dibenz(b,f)azepine-5-carboxamide

    26. Schembl420263

    27. Licarbazepine [who-dd]

    28. Schembl12356854

    29. Dtxsid50865484

    30. Hms3412j19

    31. Hms3676j19

    32. 5h-dibenz[b,f]azepine-5-carboxamide,10,11-dihydro-10-hydroxy-

    33. (+-)-10,11-dihydro-10-hydroxy-5h-dibenz(b,f)azepine-5-carboxamide

    34. Bdbm50330859

    35. Mfcd00871817

    36. Akos016011140

    37. Ab92454

    38. Am10036

    39. Sb46355

    40. Ac-37004

    41. As-10186

    42. Hy-108506

    43. Cs-0029029

    44. Ft-0666976

    45. Ft-0666977

    46. Ft-0672479

    47. Ft-0672480

    48. Ft-0672482

    49. C07493

    50. 10,11-dihydro-10-hydroxycarbamazepine Solution

    51. 10,11-dihydro-10-hydroxycarbazepine-d4(major)

    52. 331d928

    53. A876488

    54. J-017477

    55. Q6542996

    56. 10,11-dihydro-10-hydroxycarbamazepine, Analytical Standard

    57. 10,11-dihydro-10-hydroxy Carbamazepine-with Exact Weight Protocol

    58. 10,11-dihydro-10-hydroxy-5h-dibenz(z)[b,f]azepin-5-carboxamide

    59. 10-hydroxy-10,11-dihydro-5h-dibenzo[b,f]azepine-5 Carboxamide

    60. 10-hydroxy-10,11-dihydrocarbamazepine 1.0 Mg/ml In Acetonitrile

    61. 10,11-dihydro-10-hydroxycarbamazepine 100 Microg/ml In Acetonitrile

    62. 10-hydroxy-10,11-dihydro-dibenzo[b,f]azepine-5-carboxylic Acid Amide

    63. Racemic 10-hydroxy-10,11-dihydro-5h-dibenzo[b,f]azepine-5-carboxamide

    64. ( Inverted Exclamation Marka)-10-hydroxy-10,11-dihydro-5h-dibenz[b,f]azepine-5-carboxamide

    65. 10,11-dihydro-10-hydroxycarbamazepine Solution, 1.0 Mg/ml In Acetonitrile, Ampule Of 1 Ml, Certified Reference Material

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 254.28 g/mol
    Molecular Formula C15H14N2O2
    XLogP31.4
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count0
    Exact Mass254.105527694 g/mol
    Monoisotopic Mass254.105527694 g/mol
    Topological Polar Surface Area66.6 Ų
    Heavy Atom Count19
    Formal Charge0
    Complexity347
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 Metabolism/Metabolites

    10-hydroxycarbazepine has known human metabolites that include (2S,3S,4S,5R)-6-[(11-carbamoyl-5,6-dihydrobenzo[b][1]benzazepin-5-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid.

    S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560