1. 4-hydroxybenzoate
2. 4-hydroxybenzoic Acid, Calcium Salt
3. 4-hydroxybenzoic Acid, Copper(2+)(1:1) Salt
4. 4-hydroxybenzoic Acid, Dilithium Salt
5. 4-hydroxybenzoic Acid, Dipotassium Salt
6. 4-hydroxybenzoic Acid, Disodium Salt
7. 4-hydroxybenzoic Acid, Monopotassium Salt
8. 4-hydroxybenzoic Acid, Monosodium Salt
9. 4-hydroxybenzoic Acid, Monosodium Salt, 11c-labeled
10. P-hydroxybenzoate
11. Para-hydroxybenzoic Acid
12. Sodium P-hydroxybenzoate Tetrahydrate
1. 99-96-7
2. P-hydroxybenzoic Acid
3. 4-carboxyphenol
4. P-salicylic Acid
5. Benzoic Acid, 4-hydroxy-
6. Benzoic Acid, P-hydroxy-
7. Para-hydroxybenzoic Acid
8. P-carboxyphenol
9. 4-hydroxybenzoesaeure
10. Paraben-acid
11. 4-hydroxy Benzoic Acid
12. P-oxybenzoesaure [german]
13. 4-hydroxybenzoicacid
14. Phba
15. 4-hydroxy-benzoic Acid
16. Hydroxybenzoic Acid
17. Acido P-idrossibenzoico [italian]
18. Kyselina 4-hydroxybenzoova
19. Kyselina 4-hydroxybenzoova [czech]
20. Nsc 4961
21. Parahydroxybenzoic Acid
22. Hydroxybenzoic Acid, Para
23. P-hydroxy Benzoic Acid
24. P-hydroxy-benzoic Acid
25. Hydroxybenzenecarboxylic Acid
26. 4-hba
27. Hsdb 7233
28. Chembl441343
29. Jg8z55y12h
30. Einecs 202-804-9
31. Chebi:30763
32. Nsc-4961
33. Mfcd00002547
34. Ai3-01003
35. Benzoic Acid, 4-hydroxy-, Homopolymer
36. 3pcc
37. 3pch
38. 4-hydroxy-benzoate
39. Dsstox_cid_6647
40. Dsstox_rid_78173
41. Dsstox_gsid_26647
42. 30729-36-3
43. Benzoic Acid, P-hydroxy
44. Benzoic Acid, 4-hydroxy
45. Wln: Qvr Dq
46. P-oxybenzoesaure
47. Cas-99-96-7
48. Nsc4961
49. Acido P-idrossibenzoico
50. Db04242
51. Ncgc00166040-01
52. Phb
53. Unii-jg8z55y12h
54. C00156
55. P-salicylate
56. Ae-848/32195059
57. Ccris 8812
58. P-hydroxy-benzoate
59. Para-salicylic Acid
60. 4-hydoxybenzoic Acid
61. 4-hyroxybenzoic Acid
62. Phenol Derivative, 8
63. 4-hydroxylbenzoic Acid
64. 4-hydroxy-benzoesaeure
65. 4-hydroxybenzoi C Acid
66. 4-hydroxyl Benzoic Acid
67. 4-hydroxybenzoate, Iii
68. Para-hydroxy Benzoic Acid
69. Para Hydroxy Benzoic Acid
70. Bmse000092
71. Bmse000583
72. Ec 202-804-9
73. Schembl4110
74. Bidd:er0706
75. 4-hydroxybenzenecarboxylic Acid
76. P-hydroxybenzoic Acid, Reagent
77. Dtxsid3026647
78. Fema No. 3986
79. Bdbm26194
80. Salicylic Acid Related Compound A
81. Lr-68
82. Zinc332752
83. P-hydroxybenzoic Acid [mi]
84. Cs-d1180
85. Hy-y0264
86. Str01287
87. Tox21_202342
88. Tox21_303301
89. Ac-008
90. Bbl011981
91. S3754
92. Stl138745
93. 4-hydroxybenzoic Acid [fhfi]
94. 4-hydroxybenzoic Acid [hsdb]
95. 4-hydroxybenzoic Acid [inci]
96. 4-hydroxybenzoic Acid, >=99%, Fg
97. Akos000119033
98. Am87513
99. Ccg-266143
100. Ncgc00166040-02
101. Ncgc00257058-01
102. Ncgc00259891-01
103. Ft-0618695
104. Ft-0669322
105. H0207
106. 4-hydroxybenzoic Acid, Reagentplus(r), 99%
107. D86505
108. Salicylic Acid Impurity A [ep Impurity]
109. 4-hydroxybenzoic Acid, Reagentplus(r), >=99%
110. 4-hydroxybenzoic Acid, Puriss., >=99.0% (t)
111. A858402
112. Q229970
113. Salicylic Acid Related Compound A [usp-rs]
114. 46dd083d-bfd3-4ce1-b2d9-6c6d5fefd3d9
115. J-660066
116. W-100004
117. 4-hydroxybenzoic Acid, Vetec(tm) Reagent Grade, 99%
118. Acetylsalicylic Acid Impurity A [ep Impurity]
119. Propyl Hydroxybenzoate Impurity A [ep Impurity]
120. F2191-0237
121. Salicylic Acid Related Compound A [usp Impurity]
122. Z1259273385
123. Methyl Parahydroxybenzoate Impurity A [ep Impurity]
124. 4-hydroxybenzoic Acid, Certified Reference Material, Tracecert(r)
125. 4-hydroxybenzoic Acid, Pharmaceutical Secondary Standard; Certified Reference Material
126. Salicylic Acid Related Compound A, United States Pharmacopeia (usp) Reference Standard
| Molecular Weight | 138.12 g/mol |
|---|---|
| Molecular Formula | C7H6O3 |
| XLogP3 | 1.6 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 1 |
| Exact Mass | 138.031694049 g/mol |
| Monoisotopic Mass | 138.031694049 g/mol |
| Topological Polar Surface Area | 57.5 Ų |
| Heavy Atom Count | 10 |
| Formal Charge | 0 |
| Complexity | 125 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
...Groups of 4-8 rabbits were given 4-hydroxybenzoic acid at a dose of 100, 250, 500, 1000, or 1500 mg/kg bw by gavage every 3-7 days. Urine was collected continuously and analysed for metabolites. The total urinary recovery of the test material ranged from 84% to 104%. Glucuronic acid and sulfate conjugates were also detected in the urine, at 10-35% and 4-7%, respectively. The concentrations of all the metabolites returned to background values within 24 hr after dosing.
JECFA; WHO Food Additives Series 48: Safety Evaluation of Certain Food Additives and Contaminants: Hydroxy- and Alkoxy-substituted Benzyl Derivatives (2002). Available from, as of July 23, 2004: https://www.inchem.org/documents/jecfa/jecmono/v48je15.htm
In rabbits, 96% of a single oral dose of 400 mg/kg bw 4-hydroxybenzaldehyde was excreted in the urine within 24 hr as 4-hydroxybenzoic acid and its glycine, glucuronic acid, and sulfate conjugates.
JECFA; WHO Food Additives Series 48: Safety Evaluation of Certain Food Additives and Contaminants: Hydroxy- and Alkoxy-substituted Benzyl Derivatives (2002). Available from, as of July 23, 2004: https://www.inchem.org/documents/jecfa/jecmono/v48je15.htm
...Metabolism in the rat of p-hydroxybenzoic acid and its methyl, ethyl and propyl esters resulted in the appearance in the urine first of free p-hydroxybenzoic acid, followed by the glucuronide and p-hydroxyhippuric acid, the concentration of which increased as that of the free p-hydroxybenzoic acid /decreased/.
JECFA; WHO Food Additives Series 5: Toxicological evaluation of some food additives including anticaking agents, antimicrobials, antioxidants, emulsifiers and thickening agents (1974). Available from, as of July 23, 2004: https://www.inchem.org/documents/jecfa/jecmono/v05je13.htm
