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    Acycloguanosine

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    DIGITAL CONTENT

    GLOBAL SALES INFORMATION

    MARKET PLACE

    REF. STANDARDS & IMPURITIES

    ANALYTICAL

    PharmaCompass
    $ API Ref.Price (USD/KG) : 599Xls

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    2D Structure
    Also known as: Aciclovir sodium, 69657-51-8, Sodium acyclovir, Sodium 2-((2-amino-6-oxo-1h-purin-9(6h)-yl)methoxy)ethanolate, Acyclovir sodium salt, Bw 248u sodium
    Molecular Formula
    C8H10N5NaO3
    Molecular Weight
    247.19  g/mol
    InChI Key
    RMLUKZWYIKEASN-UHFFFAOYSA-M
    A GUANOSINE analog that acts as an antimetabolite. Viruses are especially susceptible. Used especially against herpes.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;2-amino-9-(2-hydroxyethoxymethyl)purin-6-olate
    2.1.2 InChI
    InChI=1S/C8H11N5O3.Na/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14;/h3,14H,1-2,4H2,(H3,9,11,12,15);/q;+1/p-1
    2.1.3 InChI Key
    RMLUKZWYIKEASN-UHFFFAOYSA-M
    2.1.4 Canonical SMILES
    C1=NC2=C(N1COCCO)N=C(N=C2[O-])N.[Na+]
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. 9-((2-hydroxyethoxy)methyl)guanine

    2. Aci Sanorania

    3. Aci-sanorania

    4. Acic

    5. Aciclobeta

    6. Aciclostad

    7. Aciclovir

    8. Aciclovir Alonga

    9. Aciclovir Sanorania

    10. Aciclovir Von Ct

    11. Aciclovir-sanorania

    12. Acifur

    13. Acipen Solutab

    14. Acivir

    15. Activir

    16. Acyclo V

    17. Acyclo-v

    18. Acycloguanosine

    19. Acyclovir

    20. Alonga, Aciclovir

    21. Antiherpes Creme

    22. Avirax

    23. Cicloferon

    24. Clonorax

    25. Cusiviral

    26. Genvir

    27. Herpetad

    28. Herpofug

    29. Herpotern

    30. Herpoviric

    31. Isavir

    32. Laciken

    33. Mapox

    34. Maynar

    35. Milavir

    36. Opthavir

    37. Sodium, Acyclovir

    38. Solutab, Acipen

    39. Supraviran

    40. Viclovir

    41. Vipral

    42. Virax Puren

    43. Virax-puren

    44. Viraxpuren

    45. Virherpes

    46. Virmen

    47. Virolex

    48. Virupos

    49. Virzin

    50. Wellcome 248u

    51. Wellcome-248u

    52. Wellcome248u

    53. Zoliparin

    54. Zovirax

    55. Zyclir

    2.2.2 Depositor-Supplied Synonyms

    1. Aciclovir Sodium

    2. 69657-51-8

    3. Sodium Acyclovir

    4. Sodium 2-((2-amino-6-oxo-1h-purin-9(6h)-yl)methoxy)ethanolate

    5. Acyclovir Sodium Salt

    6. Bw 248u Sodium

    7. Mfcd01694138

    8. Bw-248u Sodium

    9. Bw-248u-sodium

    10. Sodium 2-amino-9-((2-hydroxyethoxy)methyl)-9h-purin-6-olate

    11. Sodium 2-amino-9-[(2-hydroxyethoxy)methyl]purin-6-olate

    12. 9-((2-hydroxyethoxy)methyl)guanine Monosodium Salt

    13. Aciclovir Natrium

    14. Bw 248u

    15. Zovirax Sterile Powder

    16. 927l42j563

    17. Acycloguanosine Sodium (obs.)

    18. Unii-927l42j563

    19. 6h-purin-6-one, 2-amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-, Monosodium Salt

    20. Schembl40722

    21. Chembl1200380

    22. Bcp13172

    23. Akos015896105

    24. 2-amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6h-purin-6-one Monosodium Salt

    25. As-12705

    26. Sy027836

    27. O12074

    28. Q27271485

    29. Sodium2-amino-9-((2-hydroxyethoxy)methyl)-9h-purin-6-olate

    30. 6h-purin-6-one, 1,9-dihydro-2-amino-9-((2-hydroxyethoxy)methyl)-, Monosodium Salt

    2.3 Create Date
    2008-02-05
    3 Chemical and Physical Properties
    Molecular Weight 247.19 g/mol
    Molecular Formula C8H10N5NaO3
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count7
    Rotatable Bond Count4
    Exact Mass247.06813348 g/mol
    Monoisotopic Mass247.06813348 g/mol
    Topological Polar Surface Area122 Ų
    Heavy Atom Count17
    Formal Charge0
    Complexity237
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameAcyclovir sodium
    Drug LabelAcyclovir is a synthetic nucleoside analog active against herpes viruses. Acyclovir for Injection USP is a sterile lyophilized powder for intravenous administration only. Each 500 mg vial contains 500 mg of acyclovir and 49 mg of sodium, and each 100...
    Active IngredientAcyclovir sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 50mg base/ml; eq 500mg base/vial; eq 1gm base/vial
    Market StatusPrescription
    CompanyBedford; Fresenius Kabi Usa; Aurobindo Pharma

    2 of 2  
    Drug NameAcyclovir sodium
    Drug LabelAcyclovir is a synthetic nucleoside analog active against herpes viruses. Acyclovir for Injection USP is a sterile lyophilized powder for intravenous administration only. Each 500 mg vial contains 500 mg of acyclovir and 49 mg of sodium, and each 100...
    Active IngredientAcyclovir sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 50mg base/ml; eq 500mg base/vial; eq 1gm base/vial
    Market StatusPrescription
    CompanyBedford; Fresenius Kabi Usa; Aurobindo Pharma

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Antiviral Agents

    Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC]; Herpes Zoster Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC]; Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor [EPC]; Nucleoside Analog [EXT]; DNA Polymerase Inhibitors [MoA]