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    Althiazide

    ACTIVE PHARMA INGREDIENTS

    MARKET PLACE

    PharmaCompass
    Xls

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    2D Structure
    Also known as: Altizide, 5588-16-9, (-)-altizide, Altizide, (+)-, (+)-altizide, Althiazide [usan]
    Molecular Formula
    C11H14ClN3O4S3
    Molecular Weight
    383.9  g/mol
    InChI Key
    VGLGVJVUHYTIIU-UHFFFAOYSA-N
    FDA UNII
    D9KLS88BLV
    Althiazide is an agent, also known as altizide, belonging to the class of thiazide diuretics with antihypertensive activity.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-16,2,4-benzothiadiazine-7-sulfonamide
    2.1.2 InChI
    InChI=1S/C11H14ClN3O4S3/c1-2-3-20-6-11-14-8-4-7(12)9(21(13,16)17)5-10(8)22(18,19)15-11/h2,4-5,11,14-15H,1,3,6H2,(H2,13,16,17)
    2.1.3 InChI Key
    VGLGVJVUHYTIIU-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C=CCSCC1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl
    2.2 Other Identifiers
    2.2.1 UNII
    D9KLS88BLV
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 3-((allylthio)methyl)-6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide

    2. Altizide

    3. Altozide

    2.3.2 Depositor-Supplied Synonyms

    1. Altizide

    2. 5588-16-9

    3. (-)-altizide

    4. Altizide, (+)-

    5. (+)-altizide

    6. Althiazide [usan]

    7. Altizide, (-)-

    8. 6-chloro-3,4-dihydro-3-[(2-propenylthio)methyl]-2h-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

    9. Altizide [inn]

    10. 3-((allylthio)methyl)-6-chloro-3,4-dihydro-2h-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide

    11. D9kls88blv

    12. 133562-97-7

    13. 133585-76-9

    14. Nsc-757786

    15. Gi8cb72b0d

    16. Ji3zo158in

    17. 2h-1,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-((2-propen-1-ylthio)methyl)-, 1,1-dioxide, (+)-

    18. 2h-1,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-((2-propen-1-ylthio)methyl)-, 1,1-dioxide, (-)-

    19. P-1779

    20. Altizide (inn)

    21. Althiazide (usan)

    22. Ncgc00094855-01

    23. Altizida

    24. Dsstox_cid_25857

    25. Dsstox_rid_81178

    26. Dsstox_gsid_45857

    27. 2h-1,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-((2-propenylthio)methyl)-, 1,1-dioxide

    28. 3-((allylthio)methyl)-6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

    29. 3-[(allylthio)methyl]-6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

    30. Altizidum

    31. Altizidum [inn-latin]

    32. Sr-05000001753

    33. Altizida [inn-spanish]

    34. Unii-d9kls88blv

    35. Unii-gi8cb72b0d

    36. Unii-ji3zo158in

    37. Althiazide-[d5]

    38. Prestwick_43

    39. 6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2h-1lambda6,2,4-benzothiadiazine-7-sulfonamide

    40. Cas-5588-16-9

    41. Einecs 226-994-8

    42. Cb 8093

    43. Spectrum_001104

    44. Starbld0016521

    45. Specplus_000833

    46. Prestwick0_000721

    47. Prestwick1_000721

    48. Prestwick2_000721

    49. Prestwick3_000721

    50. Spectrum2_001367

    51. Spectrum3_000902

    52. Spectrum4_000999

    53. Spectrum5_001725

    54. Altizide [mart.]

    55. Altizide [who-dd]

    56. P 1779

    57. Bspbio_000642

    58. Kbiogr_001437

    59. Kbioss_001584

    60. Mls002153973

    61. Divk1c_001031

    62. Divk1c_006929

    63. Schembl124525

    64. Spectrum1500804

    65. Spbio_001294

    66. Spbio_002581

    67. Altizide [ep Impurity]

    68. Bpbio1_000708

    69. Chembl599870

    70. Altizide [ep Monograph]

    71. Dtxsid3045857

    72. Chebi:91768

    73. Hms503o03

    74. Kbio1_001031

    75. Kbio1_001873

    76. Kbio2_001584

    77. Kbio2_004152

    78. Kbio2_006720

    79. Kbio3_001844

    80. Ninds_001031

    81. Hms1570a04

    82. Hms1921i12

    83. Hms2092k18

    84. Hms2097a04

    85. Hms2233o21

    86. Hms3373k04

    87. Hms3714a04

    88. Pharmakon1600-01500804

    89. Hy-b1254

    90. Tox21_111347

    91. Ccg-38982

    92. Nsc757786

    93. Akos027381757

    94. Tox21_111347_1

    95. Nsc 757786

    96. 3-allylthiomethyl-6-chlor-3,4-dihydro-2h-1,2,4-benzothiadiazin-7-sulfonamid 1,1-dioxid

    97. Idi1_001031

    98. Smp1_000012

    99. Ncgc00094855-02

    100. Ncgc00094855-03

    101. Ncgc00094855-06

    102. 2h-1,2,4-benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-, 1,1-dioxide

    103. 6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-2h-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

    104. Smr001233310

    105. Sbi-0052594.p002

    106. Db-052814

    107. Ab00053099

    108. Cs-0013046

    109. Ft-0635778

    110. D02838

    111. Ab00053099_08

    112. Sr-05000001753-1

    113. Sr-05000001753-3

    114. Brd-a56675431-001-04-0

    115. Brd-a56675431-001-07-3

    116. Altizide, European Pharmacopoeia (ep) Reference Standard

    117. 6-chloro-3,4-dihydro-3-((2-propenylthio)methyl)-2h-1,2,4-benzothiadiazine-7-sulfonamide

    118. 2h-1,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-, 1,1-dioxide

    119. 6-chloro-1,1-dioxo-3-[(prop-2-enylthio)methyl]-3,4-dihydro-2h-1$l;{6},2,4-benzothiadiazine-7-sulfonamide

    120. 6-chloro-3,4-dihydro-3-[(2-propenylthio)methyl]-2h-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 383.9 g/mol
    Molecular Formula C11H14ClN3O4S3
    XLogP30.8
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count5
    Exact Mass382.9834972 g/mol
    Monoisotopic Mass382.9834972 g/mol
    Topological Polar Surface Area160 Ų
    Heavy Atom Count22
    Formal Charge0
    Complexity614
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 ATC Code

    C03EA04

    S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355