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2D Structure
Also known as: Amperozide hcl, Hogpax, 86725-37-3, Amperozide hydrochloride [mi], 75529-73-6, 4-[4,4-bis(4-fluorophenyl)butyl]-n-ethylpiperazine-1-carboxamide;hydrochloride
Molecular Formula
C23H30ClF2N3O
Molecular Weight
438.0  g/mol
InChI Key
OEQHKNWFXHBJIT-UHFFFAOYSA-N
FDA UNII
8V2171U69N

1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[4,4-bis(4-fluorophenyl)butyl]-N-ethylpiperazine-1-carboxamide;hydrochloride
2.1.2 InChI
InChI=1S/C23H29F2N3O.ClH/c1-2-26-23(29)28-16-14-27(15-17-28)13-3-4-22(18-5-9-20(24)10-6-18)19-7-11-21(25)12-8-19;/h5-12,22H,2-4,13-17H2,1H3,(H,26,29);1H
2.1.3 InChI Key
OEQHKNWFXHBJIT-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCNC(=O)N1CCN(CC1)CCCC(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F.Cl
2.2 Other Identifiers
2.2.1 UNII
8V2171U69N
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Amperozide

2.3.2 Depositor-Supplied Synonyms

1. Amperozide Hcl

2. Hogpax

3. 86725-37-3

4. Amperozide Hydrochloride [mi]

5. 75529-73-6

6. 4-[4,4-bis(4-fluorophenyl)butyl]-n-ethylpiperazine-1-carboxamide;hydrochloride

7. 8v2171u69n

8. Ncgc00093556-01

9. 4-[4,4-bis(4-fluorophenyl)butyl]-n-ethyl-1-piperazinecarboxamide Hydrochloride

10. Dsstox_cid_25750

11. Dsstox_rid_81094

12. Dsstox_gsid_45750

13. 4-(4,4-bis(p-fluorophenyl)butyl)-n-ethyl-1-piperazinecarboxamide Hydrochloride

14. Cas-75529-73-6

15. Fg 5606

16. Fg-5606

17. Unii-8v2171u69n

18. Amperozide Hydrochloride [who-dd]

19. Amperozide Monohydrochloride

20. Mls002153519

21. Schembl1321270

22. Amperozide Hydrochloride (1:1)

23. Chembl1257106

24. Chebi:180485

25. Dtxsid501019079

26. Tox21_111208

27. Tox21_500040

28. Akos024457273

29. Tox21_111208_1

30. Lp00040

31. 4-[4,4-bis(4-fluorophenyl)butyl]-n-ethylpiperazine-1-carboxamide Hydrochloride

32. Ncgc00015081-04

33. Ncgc00260725-01

34. As-16836

35. Smr001230851

36. Eu-0100040

37. A 6976

38. Sr-01000076207

39. Sr-01000076207-1

40. Q27271058

41. 1-[4,4-bis(4-fluorophenyl)butyl]-4-(ethylcarbamoyl)piperazin-1-ium Chloride

42. 1-piperazinecarboxamide, 4-(4,4-bis(4-fluorophenyl)butyl)-n-ethyl-, Hydrochloride (1:?)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 438.0 g/mol
Molecular Formula C23H30ClF2N3O
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Exact Mass437.2045466 g/mol
Monoisotopic Mass437.2045466 g/mol
Topological Polar Surface Area35.6 Ų
Heavy Atom Count30
Formal Charge0
Complexity461
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antipsychotic Agents

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)


Serotonin Antagonists

Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS. (See all compounds classified as Serotonin Antagonists.)


Psychotropic Drugs

A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents). (See all compounds classified as Psychotropic Drugs.)