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    Amperozide

    PharmaCompass
    Xls

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    2D Structure
    Also known as: Amperozide hcl, Hogpax, 86725-37-3, Amperozide hydrochloride [mi], 75529-73-6, 4-[4,4-bis(4-fluorophenyl)butyl]-n-ethylpiperazine-1-carboxamide;hydrochloride
    Molecular Formula
    C23H30ClF2N3O
    Molecular Weight
    438.0  g/mol
    InChI Key
    OEQHKNWFXHBJIT-UHFFFAOYSA-N
    FDA UNII
    8V2171U69N
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-[4,4-bis(4-fluorophenyl)butyl]-N-ethylpiperazine-1-carboxamide;hydrochloride
    2.1.2 InChI
    InChI=1S/C23H29F2N3O.ClH/c1-2-26-23(29)28-16-14-27(15-17-28)13-3-4-22(18-5-9-20(24)10-6-18)19-7-11-21(25)12-8-19;/h5-12,22H,2-4,13-17H2,1H3,(H,26,29);1H
    2.1.3 InChI Key
    OEQHKNWFXHBJIT-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CCNC(=O)N1CCN(CC1)CCCC(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    8V2171U69N
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Amperozide

    2.3.2 Depositor-Supplied Synonyms

    1. Amperozide Hcl

    2. Hogpax

    3. 86725-37-3

    4. Amperozide Hydrochloride [mi]

    5. 75529-73-6

    6. 4-[4,4-bis(4-fluorophenyl)butyl]-n-ethylpiperazine-1-carboxamide;hydrochloride

    7. 8v2171u69n

    8. Ncgc00093556-01

    9. 4-[4,4-bis(4-fluorophenyl)butyl]-n-ethyl-1-piperazinecarboxamide Hydrochloride

    10. Dsstox_cid_25750

    11. Dsstox_rid_81094

    12. Dsstox_gsid_45750

    13. 4-(4,4-bis(p-fluorophenyl)butyl)-n-ethyl-1-piperazinecarboxamide Hydrochloride

    14. Cas-75529-73-6

    15. Fg 5606

    16. Fg-5606

    17. Unii-8v2171u69n

    18. Amperozide Hydrochloride [who-dd]

    19. Amperozide Monohydrochloride

    20. Mls002153519

    21. Schembl1321270

    22. Amperozide Hydrochloride (1:1)

    23. Chembl1257106

    24. Chebi:180485

    25. Dtxsid501019079

    26. Tox21_111208

    27. Tox21_500040

    28. Akos024457273

    29. Tox21_111208_1

    30. Lp00040

    31. 4-[4,4-bis(4-fluorophenyl)butyl]-n-ethylpiperazine-1-carboxamide Hydrochloride

    32. Ncgc00015081-04

    33. Ncgc00260725-01

    34. As-16836

    35. Smr001230851

    36. Eu-0100040

    37. A 6976

    38. Sr-01000076207

    39. Sr-01000076207-1

    40. Q27271058

    41. 1-[4,4-bis(4-fluorophenyl)butyl]-4-(ethylcarbamoyl)piperazin-1-ium Chloride

    42. 1-piperazinecarboxamide, 4-(4,4-bis(4-fluorophenyl)butyl)-n-ethyl-, Hydrochloride (1:?)

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 438.0 g/mol
    Molecular Formula C23H30ClF2N3O
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count7
    Exact Mass437.2045466 g/mol
    Monoisotopic Mass437.2045466 g/mol
    Topological Polar Surface Area35.6 Ų
    Heavy Atom Count30
    Formal Charge0
    Complexity461
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antipsychotic Agents

    Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)

    Serotonin Antagonists

    Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS. (See all compounds classified as Serotonin Antagonists.)

    Psychotropic Drugs

    A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents). (See all compounds classified as Psychotropic Drugs.)