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    Technical details about Amtolmetin Guacil, learn more about the structure, uses, toxicity, action, side effects and more

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    Amtolmetin Guacil

    APIs // Active Pharmaceutical Ingredients

    DOSSIERs // Finished Dosage Forms

    GLOBAL SALES INFORMATION

    PharmaCompass

    Biophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

    Athena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

    2D Structure
    1. Also known as: 87344-06-7, 2-methoxyphenyl 2-(2-(1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl)acetamido)acetate, Artromed, Amtolmetin guacyl, St 679, St-679
    Molecular Formula
    C24H24N2O5
    Molecular Weight
    420.5  g/mol
    InChI Key
    CWJNMKKMGIAGDK-UHFFFAOYSA-N
    FDA UNII
    323A00CRO9
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (2-methoxyphenyl) 2-[[2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetyl]amino]acetate
    2.1.2 InChI
    InChI=1S/C24H24N2O5/c1-16-8-10-17(11-9-16)24(29)19-13-12-18(26(19)2)14-22(27)25-15-23(28)31-21-7-5-4-6-20(21)30-3/h4-13H,14-15H2,1-3H3,(H,25,27)
    2.1.3 InChI Key
    CWJNMKKMGIAGDK-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1=CC=C(C=C1)C(=O)C2=CC=C(N2C)CC(=O)NCC(=O)OC3=CC=CC=C3OC
    2.2 Other Identifiers
    2.2.1 UNII
    323A00CRO9
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 2-methoxyphenyl 1-methyl-5-(4-methylbenzoylpyrrol)-2-acetamidoacetate

    2. Amtolmetin Guacyl

    3. Amtolmetineguacil

    4. Artromed

    5. Med 15

    6. Med-15

    7. Med15

    8. St 679

    9. St-679

    2.3.2 Depositor-Supplied Synonyms

    1. 87344-06-7

    2. 2-methoxyphenyl 2-(2-(1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl)acetamido)acetate

    3. Artromed

    4. Amtolmetin Guacyl

    5. St 679

    6. St-679

    7. Med 15

    8. Amtolmetin Guacil [inn]

    9. Med-15

    10. Finrid

    11. Med15

    12. 104076-16-6

    13. 2-methoxyphenyl 1-methyl-5-p-methylbenzoylpyrrole-2-acetoamidoacetate

    14. 323a00cro9

    15. (2-methoxyphenyl) 2-[[2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetyl]amino]acetate

    16. Amtolmetin Guacil (inn)

    17. N-((1-methyl-5-p-toluoylpyrrol-2-yl)acetyl)glycine O-methoxyphenyl Ester

    18. 2-methoxyphenyl (2-(1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl)acetyl)glycinate

    19. Eufans

    20. Amtolmetine Guacil

    21. Amtolmetina Guacilo

    22. Amtolmetinum Guacilum

    23. Amtolmetine Guacil [inn-french]

    24. Amtolmetina Guacilo [inn-spanish]

    25. Amtolmetinum Guacilum [inn-latin]

    26. Unii-323a00cro9

    27. Amtolmetin-guacil

    28. Artromed (tn)

    29. N-((1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl)acetyl)glycine 2-methoxyphenyl Ester

    30. Schembl24555

    31. Mls006010220

    32. Amtolmetin Guacil [mi]

    33. Chembl1766570

    34. Dtxsid50236291

    35. Amtolmetin Guacil [mart.]

    36. Chebi:135678

    37. St679

    38. Zinc596929

    39. Amtolmetin Guacil [who-dd]

    40. Bcp28767

    41. Mfcd00866153

    42. Stl451031

    43. Akos015895070

    44. Glycine, N-((1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl)acetyl)-, 2-methoxyphenyl Ester

    45. Glycine, N-((5-benzoyl-1-methyl-1h-pyrrol-2-yl)acetyl)-, 2-methoxyphenyl Ester

    46. N-[2-[1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl]acetyl]glycine 2-methoxyphenyl Ester

    47. As-30751

    48. Smr004701308

    49. Hy-107320

    50. Cs-0028135

    51. Ft-0659812

    52. D07453

    53. 344a067

    54. A842102

    55. Sr-01000945065

    56. Q4748890

    57. Sr-01000945065-1

    58. (2-methoxyphenyl)2-[[2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetyl]amino] Acetate

    59. 2-methoxyphenyl 2-(1-methyl-5-(4-methylbenzoyl)-1h-pyrrole-2-acetylamino)acetate

    60. 2-methoxyphenyl 2-{2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetamido}acetate

    61. 2-methoxyphenyl N-({1-methyl-5-[(4-methylphenyl)carbonyl]-1h-pyrrol-2-yl}acetyl)glycinate

    62. 2-methoxyphenyl2-(1-methyl-5-(4-methylbenzoyl)-1h-pyrrole-2-acetylamino)acetate

    63. (2-methoxyphenyl) 2-[2-[1-methyl-5-(4-methylphenyl)carbonyl-pyrrol-2-yl]ethanoylamino]ethanoate

    64. 2-[[2-[1-methyl-5-[(4-methylphenyl)-oxomethyl]-2-pyrrolyl]-1-oxoethyl]amino]acetic Acid (2-methoxyphenyl) Ester

    65. Amtolmetin Guacil; 2-methoxyphenyl 2-(1-methyl-5-(4-methylbenzoyl)-1h-pyrrole-2-acetylamino)acetate

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 420.5 g/mol
    Molecular Formula C24H24N2O5
    XLogP34
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count9
    Exact Mass420.16852187 g/mol
    Monoisotopic Mass420.16852187 g/mol
    Topological Polar Surface Area86.6 Ų
    Heavy Atom Count31
    Formal Charge0
    Complexity632
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Inflammatory Agents, Non-Steroidal

    Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)

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