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    Technical details about Antineoplaston A10, learn more about the structure, uses, toxicity, action, side effects and more

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    Antineoplaston A10

    ACTIVE PHARMA INGREDIENTS

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    2D Structure
    Also known as: 91531-30-5, Antineoplaston a 10, N-[(3s)-2,6-dioxopiperidin-3-yl]-2-phenylacetamide, Atengenal, 16vy3tm7zo, Antineoplaston a-10
    Molecular Formula
    C13H14N2O3
    Molecular Weight
    246.26  g/mol
    InChI Key
    OQGRFQCUGLKSAV-JTQLQIEISA-N
    FDA UNII
    16VY3TM7ZO
    Antineoplaston A10 is a piperidinedione antineoplaston with potential antineoplastic activity. Antineoplaston A10 was originally isolated from human urine but is now synthetically derived. This agent intercalates into DNA, resulting in cell cycle arrest in G1 phase, reduction of mitosis, and decreased protein synthesis. Antineoplaston A10 may also inhibit ras-oncogene expression and activate tumor suppressor gene p53, leading to cell differentiation and apoptosis. (NCI04)
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N-[(3S)-2,6-dioxopiperidin-3-yl]-2-phenylacetamide
    2.1.2 InChI
    InChI=1S/C13H14N2O3/c16-11-7-6-10(13(18)15-11)14-12(17)8-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,14,17)(H,15,16,18)/t10-/m0/s1
    2.1.3 InChI Key
    OQGRFQCUGLKSAV-JTQLQIEISA-N
    2.1.4 Canonical SMILES
    C1CC(=O)NC(=O)C1NC(=O)CC2=CC=CC=C2
    2.1.5 Isomeric SMILES
    C1CC(=O)NC(=O)[C@H]1NC(=O)CC2=CC=CC=C2
    2.2 Other Identifiers
    2.2.1 UNII
    16VY3TM7ZO
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 3-((phenylacetyl)amino)-2,6-piperidinedione

    2. 3-(n-phenylacetylamino)-2,6-piperidinedione

    3. A 10

    4. A-10

    5. A10

    6. Antineoplaston-a10

    7. N-(2,6-dioxo-3-piperidinyl)benzeneacetamide

    2.3.2 Depositor-Supplied Synonyms

    1. 91531-30-5

    2. Antineoplaston A 10

    3. N-[(3s)-2,6-dioxopiperidin-3-yl]-2-phenylacetamide

    4. Atengenal

    5. 16vy3tm7zo

    6. Antineoplaston A-10

    7. A-10

    8. Antineoplaston-a10

    9. Benzeneacetamide, N-(2,6-dioxo-3-piperidinyl)-, (s)-

    10. A 10

    11. Unii-16vy3tm7zo

    12. Cengenal

    13. 3-(n-phenylacetylamino)-2,6-piperidinedione

    14. N-(2,6-dioxo-3-piperidinyl)benzeneacetamide

    15. 3-((phenylacetyl)amino)-2,6-piperidinedione

    16. Antineoplastona10

    17. Antineoplaston A10 Capsules

    18. Anp-a10

    19. A10

    20. Chembl1980825

    21. Schembl20772654

    22. Dtxsid00919683

    23. Zinc1590366

    24. Mfcd26961095

    25. Nsc619130

    26. N-(6-hydroxy-2-oxo-2,3,4,5-tetrahydropyridin-3-yl)-2-phenylethanimidic Acid

    27. Antineoplaston A 10 [who-dd]

    28. Db11702

    29. Nsc-619130

    30. As-84380

    31. Nci60_005691

    32. Hy-128553

    33. Cs-0095862

    34. D80851

    35. (s)-n-(2,6-dioxopiperidin-3-yl)-2-phenylacetamide

    36. N-[(3s)-2,6-dioxo-3-piperidyl]-2-phenyl-acetamide

    37. Q27251844

    38. Benzeneacetamide, N-((3s)-2,6-dioxo-3-piperidinyl)-

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 246.26 g/mol
    Molecular Formula C13H14N2O3
    XLogP30.4
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count3
    Exact Mass246.10044231 g/mol
    Monoisotopic Mass246.10044231 g/mol
    Topological Polar Surface Area75.3 Ų
    Heavy Atom Count18
    Formal Charge0
    Complexity348
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1