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    AZD1656

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    PharmaCompass
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    2D Structure
    Also known as: Azd-1656, Azd1656, 919783-22-5, Azd 1656, 660m185x4d, 3-((5-(azetidin-1-ylcarbonyl)pyrazin-2-yl)oxy)-5-((1s)-2-methoxy-1-methylethoxy)-n-(5-methylpyrazin-2-yl)benzamide
    Molecular Formula
    C24H26N6O5
    Molecular Weight
    478.5  g/mol
    InChI Key
    FJEJHJINOKKDCW-INIZCTEOSA-N
    FDA UNII
    660M185X4D
    AZD-1656 is under investigation in clinical trial NCT00747175 (A Study to Evaluate Safety, Tolerability and P-Glucose After Multiple Ascending Oral Doses of AZD1656 in Type 2 Diabetes).
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    3-[5-(azetidine-1-carbonyl)pyrazin-2-yl]oxy-5-[(2S)-1-methoxypropan-2-yl]oxy-N-(5-methylpyrazin-2-yl)benzamide
    2.1.2 InChI
    InChI=1S/C24H26N6O5/c1-15-10-27-21(12-25-15)29-23(31)17-7-18(34-16(2)14-33-3)9-19(8-17)35-22-13-26-20(11-28-22)24(32)30-5-4-6-30/h7-13,16H,4-6,14H2,1-3H3,(H,27,29,31)/t16-/m0/s1
    2.1.3 InChI Key
    FJEJHJINOKKDCW-INIZCTEOSA-N
    2.1.4 Canonical SMILES
    CC1=CN=C(C=N1)NC(=O)C2=CC(=CC(=C2)OC(C)COC)OC3=NC=C(N=C3)C(=O)N4CCC4
    2.1.5 Isomeric SMILES
    CC1=CN=C(C=N1)NC(=O)C2=CC(=CC(=C2)O[C@@H](C)COC)OC3=NC=C(N=C3)C(=O)N4CCC4
    2.2 Other Identifiers
    2.2.1 UNII
    660M185X4D
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Azd1656

    2.3.2 Depositor-Supplied Synonyms

    1. Azd-1656

    2. Azd1656

    3. 919783-22-5

    4. Azd 1656

    5. 660m185x4d

    6. 3-((5-(azetidin-1-ylcarbonyl)pyrazin-2-yl)oxy)-5-((1s)-2-methoxy-1-methylethoxy)-n-(5-methylpyrazin-2-yl)benzamide

    7. 3-{[5-(azetidin-1-ylcarbonyl)pyrazin-2-yl]oxy}-5-[(1s)-2-methoxy-1-methylethoxy]-n-(5-methylpyrazin-2-yl)benzamide

    8. Schembl321593

    9. Gtpl7701

    10. Chembl3219124

    11. Unii-660m185x4d

    12. Azd 1656 [who-dd]

    13. At32772

    14. Db14810

    15. Ba171838

    16. Cid 16039797

    17. Hy-15675

    18. Cs-0008226

    19. E77313

    20. Q27074714

    21. (s)-3-(5-(azetidine-1-carbonyl)pyrazin-2-yloxy)-5-(1-methoxypropan-2-yloxy)-n-(5-methylpyrazin-2-yl)benzamide

    22. Benzamide, 3-((5-(1-azetidinylcarbonyl)-2-pyrazinyl)oxy)-5-((1s)-2-methoxy-1-methylethoxy)-n-(5-methyl-2-pyrazinyl)-

    2.4 Create Date
    2007-04-16
    3 Chemical and Physical Properties
    Molecular Weight 478.5 g/mol
    Molecular Formula C24H26N6O5
    XLogP31.3
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count9
    Rotatable Bond Count9
    Exact Mass478.19646795 g/mol
    Monoisotopic Mass478.19646795 g/mol
    Topological Polar Surface Area129 Ų
    Heavy Atom Count35
    Formal Charge0
    Complexity710
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1