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1. Methylene Bis-benzotriazolyl Tetramethylphenol
2. Tinosorb M
1. 103597-45-1
2. Tinosorb M
3. Ultraviolet Absorbent Uv-360
4. Mbbt
5. Uv-360
6. Fat 75'634
7. Milestab-360
8. Tinuvin-360
9. Nsc-759873
10. 8nt850t0ys
11. 2-(benzotriazol-2-yl)-6-[[3-(benzotriazol-2-yl)-2-hydroxy-5-(2,4,4-trimethylpentan-2-yl)phenyl]methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol
12. 2,2'-methylenebis[6-(benzotriazol-2-yl)-4-tert-octylphenol]
13. Fat-75634
14. Ncgc00167544-01
15. 6,6'-methylenebis(2-(2h-benzo[d][1,2,3]triazol-2-yl)-4-(2-methylheptan-2-yl)phenol)
16. Phenol, 2,2'-methylenebis(6-(2h-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)-
17. Phenol, 2,2'-methylenebis[6-(2h-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)-
18. Bisoctrizole [usan]
19. 2,2'-methylenebis
20. Bisoctrizole (usp/inn)
21. Bisoctrizole [mi]
22. Bisoctrizole [inn]
23. Dsstox_cid_26703
24. Dsstox_rid_81837
25. Unii-8nt850t0ys
26. Dsstox_gsid_46703
27. Schembl39191
28. Bisoctrizole [mart.]
29. Ultraviolet Absorber Uv-360
30. Bisoctrizole [usp-rs]
31. Bisoctrizole [who-dd]
32. Bisoctrizole [usan:usp:inn]
33. Chembl2104957
34. Dtxsid2046703
35. Bisoctrizole, Analytical Standard
36. Chebi:135865
37. Hms3264f09
38. Pharmakon1600-01503866
39. Bcp29317
40. Hy-b0897
41. Bisoctrizole [usp Monograph]
42. Tox21_112541
43. Mfcd00192289
44. Nsc759873
45. S4551
46. Uv 360
47. Zinc11677911
48. Akos015895745
49. Db11262
50. Nsc 759873
51. Ncgc00167544-02
52. Cas-103597-45-1
53. Ft-0642535
54. M1259
55. A14939
56. D03249
57. Ec 403-800-1
58. Ab01563348_01
59. A800767
60. Sr-01000883719
61. Tinosorb M Pound>>ultraviolet Absorbent Uv-360
62. J-525148
63. Q4918369
64. Sr-01000883719-1
65. Bis-[2-hydroxy-5-t-octyl-3-(benzotriazol-2-yl)-phe
66. Bis-[2-hydroxy-5-t-octyl-3-(benzotriazol-2-yl)-phenyl) Methane
67. Bis[3-(benzotriazol-2-yl)-2-hydroxy-5-tert-octylphenyl]methane
68. Bisoctrizole, United States Pharmacopeia (usp) Reference Standard
69. Methylene Bis-benzotriazolyl Tetramethylbutylphenol [inci]
70. 2,2'-methylene-bis[4-(1,1,3,3-tetramethylbutyl)-6-benzotriazol-2-yl-phenol]
71. 2,2'-methylenebis(6-(2-benzotriazolyl)-4-(1,1,3,3-tetramethylbutyl)phenol
72. 2,2'-methylenebis(6-(2-benzotriazolyl)-4-(1,1,3,3-tetramethylbutyl)phenol)
73. 2,2'-methylenebis(6-(2hbenzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol]
74. 2,2'-methylenebis[6-(2h-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol], 99%
75. Bisoctrizole, Pharmaceutical Secondary Standard; Certified Reference Material
76. 2-(2h-1,2,3-benzotriazol-2-yl)-6-{[3-(2h-1,2,3-benzotriazol-2-yl)-2-hydroxy-5-(2,4,4-trimethylpentan-2-yl)phenyl]methyl}-4-(2,4,4-trimethylpentan-2-yl)phenol
77. 3-(benzotriazol-2-yl)-2-[[2-(benzotriazol-2-yl)-6-hydroxy-4-(1,1,3,3-tetramethylbutyl)phenyl]methyl]-5-(1,1,3,3-tetramethylbutyl)phenol;2,2'-methylenebis[6-(2h-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol]
78. 6,6'-bis(2h-1,2,3-benzotriazol-2-yl)-4,4'-bis(2,4,4-trimethylpentan-2-yl)- 2,2'-methylenebiphenol
79. Phenol, 2,2'-methylenebis(6-(2h-benzotrialzol-2-yl)-4-(1,1,3,3-tetramethylbutyl)-
Molecular Weight | 658.9 g/mol |
---|---|
Molecular Formula | C41H50N6O2 |
XLogP3 | 12.8 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 6 |
Rotatable Bond Count | 10 |
Exact Mass | 658.39952486 g/mol |
Monoisotopic Mass | 658.39952486 g/mol |
Topological Polar Surface Area | 102 Ų |
Heavy Atom Count | 49 |
Formal Charge | 0 |
Complexity | 989 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
Indicated for use as a sunscreen agent in cosmetic products.
Under the conditions of _in vitro_ androgen competitive binding assay, bisoctrizole displayed no intrinsic androgenic, estrogenic, nor uterotrophic activity.
Absorption
A rat and human dermal penetration study _in vitro_ indicates that bisoctrizole displays minimal absorption through the skin, with only about 0.01% and 0.06 % of the applied dose penetration through the human and rat skin membrane, respectively. Despite low dermal uptake, potential bioaccumulation after repeated skin applications cannot be excluded.
Route of Elimination
No pharmacokinetic data available.
Volume of Distribution
No pharmacokinetic data available.
Clearance
No pharmacokinetic data available.
No pharmacokinetic data available.
No pharmacokinetic data available.
Bisoctrizole is an organic UV-A filter that absorbs both UV-A and UV-B rays.