1. Calciofon
2. Calcipot
3. Calcium Braun
4. Calcivitol
5. Calglucon
6. Cbg
7. Ebucin
8. Flopak Plain
9. Glucal
10. Glucobiogen
11. Gluconate De Calcium Lavoisier
12. Gluconate, Calcium
13. Gluconato Calc Fresenius
1. 299-28-5
2. Calcium D-gluconate
3. Calglucon
4. D-gluconic Acid, Calcium Salt (2:1)
5. Gluconate Calcium
6. Calcarea Gluconica
7. Calcium Di-gluconate
8. Calcium Gluconate Anhydrous
9. Gluconic Acid Calcium Salt
10. Calcium Gluconate, Anhydrous
11. Glucobiogen
12. Calciofon
13. Sqe6vb453k
14. Ins No.578
15. Ebucin
16. Gluconate De Calcium
17. Ins-578
18. Almora
19. Nsc-744619
20. 152772-65-1
21. Calcium;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanoate
22. Calcicol
23. Calcipur
24. Calglucol
25. Dragocal
26. Kalpren
27. Novocal
28. E-578
29. Calcium (2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanoate
30. Calcium Hexagluconate
31. 2,3,4,5,6-pentahydroxycaproic Acid Hemicalcium Salt
32. 18016-24-5
33. Gluconato Di Calcio
34. Calcium D-gluconate (1:2)
35. Gluconate De Calcium [french]
36. Gluconato Di Calcio [italian]
37. Ccris 1336
38. Hsdb 994
39. Calcium Gluconate [usan:jan]
40. Einecs 206-075-8
41. Unii-sqe6vb453k
42. Gluconic Acid, Calcium Salt
43. Calcii Gluconas
44. Gluconic Acid, Calcium Salt (2:1), D-
45. Gluconic Acid, Calcium Salt, D-
46. Mfcd00064209
47. Calcium Bis(d-gluconate)
48. Calcium Gluconate (usp)
49. L-gluconic Acid Calcium Salt
50. Schembl24132
51. Gluconic Acid Hemicalcium Salt
52. Calcium Gluconate [mi]
53. Chebi:3309
54. Calcium Gluconate [fcc]
55. Boron Gluconate Blend 5% 40m
56. Calcium Gluconate [hsdb]
57. Calcium Gluconate [inci]
58. Chembl2106119
59. Dtxsid2029618
60. Calcium Gluconate [vandf]
61. Calcium Gluconate [who-dd]
62. Calcium Gluconate [who-ip]
63. Akos015895893
64. Calcii Gluconas [who-ip Latin]
65. Calcium Gluconate [orange Book]
66. Db11126
67. Nsc 744619
68. Calcium Gluconate [usp Impurity]
69. Calcium Gluconate [usp Monograph]
70. As-80559
71. Calcium Gluconate Anhydrous [usp-rs]
72. G0037
73. C08133
74. D00935
75. A876351
76. Q413739
77. Calcium Gluconate, Anhydrous [ep Monograph]
78. W-202243
79. Calcium D-gluconate Gel, 2.5% W/w Aqueous Solution
80. Calcium Bis[(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanoate]
| Molecular Weight | 430.37 g/mol |
|---|---|
| Molecular Formula | C12H22CaO14 |
| Hydrogen Bond Donor Count | 10 |
| Hydrogen Bond Acceptor Count | 14 |
| Rotatable Bond Count | 8 |
| Exact Mass | 430.0635462 g/mol |
| Monoisotopic Mass | 430.0635462 g/mol |
| Topological Polar Surface Area | 283 Ų |
| Heavy Atom Count | 27 |
| Formal Charge | 0 |
| Complexity | 165 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 8 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 3 |
Some studies have shown that calcium supplementation begun in the second trimester may be effective in lowering blood pressure in pregnancy women with pregnancy-induced hypertension or pre-eclampsia, both of which may possibly be associated with increased calcium demand of the fetus during the last trimester. /Calcium supplements/
USP Convention. USPDI-Drug Information for the Health Care Professional. 14th ed. Volume I. Rockville, MD: United States Pharmacopeial Convention, Inc., 1994. (Plus Updates)., p. 698
Oral calcium salts are used as dietary supplemental therapy for person who may not get enough calcium in their regular diet. Due to increased needs, children and pregnancy women are at greatest risk. Pre- and postmenopausal women; adolescents, especially girls and the elderly may not receive adequate calcium in their diets. ... Calcium supplements are used as part of the prevention and treatment of osteoporosis in patients with an inadequate calcium intake. The use of calcium citrate may reduce the risk of kidney stones in susceptible patients. The use of water-soluble salts of calcium (ie, citrate, gluconate, and lactate) may be preferable to acid-soluble salts (ie, carbonate and phosphate) for patients with reduced stomach acid or patients taking acid-inhibiting medication, such as the histamine H2-receptor antagonists. /Calcium supplements; Included in US product labeling/
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006., p. 742
Oral calcium supplements provide a source of calcium ion for treating calcium depletion occurring in conditions such as chronic hypoparathyroidism, pseudohypoparathyroidism, osteomalacia, rickets, chronic renal failure, and hypocalcemia secondary to the administration of anticonvulsant medications. When chronic hypocalcemia is due to vitamin D deficiency oral calcium salts may be administered concomitantly with vitamin D analogs. /Calcium supplements; Included in US product labeling/
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006., p. 742
Calcium chloride and parenteral calcium gluconate are used to decrease or reverse the cardiac depressant effects of hyperkalemia on electrocardiographic (ECG) function. /Calcium supplements; Included in US product labeling/
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006., p. 742
For more Therapeutic Uses (Complete) data for CALCIUM GLUCONATE (27 total), please visit the HSDB record page.
VET: ... Calcium gluconate ... if given by iv injection, should be admin slowly ... given rapidly ... may have toxic effect on heart.
Clarke, E.G., and M. L. Clarke. Veterinary Toxicology. Baltimore, Maryland: The Williams and Wilkins Company, 1975., p. 47
Calcium gluconate ... not recommended for im use because dose must be large and danger of sterile abscess formation is too great.
Hayes, W.J., Jr., E.R. Laws Jr., (eds.). Handbook of Pesticide Toxicology Volume 1. General Principles. New York, NY: Academic Press, Inc., 1991., p. 398
Many physicians recommend that pregnant women receive multivitamin and mineral supplements, especially those pregnant women who do not consume an adequate diet and those in high-risk categories )ie, women carrying more than one fetus, heavy cigarette smokers, and alcohol and drug abusers). Taking excessive amounts of a multivitamin and mineral supplement may be harmful to the mother and/or fetus and should be avoided. /Calcium supplements/
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006., p. 742
Side/adverse effects may be more likely to occur if oral calcium supplements are taken in much larger doses than recommended (greater than 2000 to 2500 mg a day), if they are taken for a longer period of time, or if they are taken by patients with renal function impairment or milk-alkali syndrome. /Calcium supplements/
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006., p. 744
For more Drug Warnings (Complete) data for CALCIUM GLUCONATE (15 total), please visit the HSDB record page.
Oral calcium salts are used as dietary supplemental therapy for person who may not get enough calcium in their regular diet. Calcium gluconate is used as a cardioprotective agent in high blood potassium. Calcium gluconate is the antidote for magnesium sulfate toxicity.
Calcium Gluconate is the gluconate salt of calcium. An element or mineral necessary for normal nerve, muscle, and cardiac function, calcium as the gluconate salt helps to maintain calcium balance and prevent bone loss when taken orally. This agent may also be chemopreventive for colon and other cancers.
A - Alimentary tract and metabolism
A12 - Mineral supplements
A12A - Calcium
A12AA - Calcium
A12AA03 - Calcium gluconate
D - Dermatologicals
D11 - Other dermatological preparations
D11A - Other dermatological preparations
D11AX - Other dermatologicals
D11AX03 - Calcium gluconate
Absorption
Approximately one-fifth to one-third of orally administered calcium is absorbed in the small intestine, depending on presence of vitamin D metabolites, pH in lumen, and on dietary factors, such as calcium binding to fiber or phytates. Calcium absorption is increased when a calcium deficiency is present or when a patient is on a low-calcium diet. In patients with achlorhydria or hypochlorhydria, calcium absorption, especially with the carbonate salt, may be reduced.
Route of Elimination
Renal (20%) - The amount excreted in the urine varies with degree of calcium absorption and whether there is excessive bone loss or failure of renal conservation. Fecal (80%) - Consists mainly of nonabsorbed calcium, with only a small amount of endogenous fecal calcium excreted.
Volume of Distribution
Not available
Approximately one-fifth to one-third of orally administered calcium is absorbed in the small intestine, depending on presence of vitamin D metabolites, pH in lumen, and on dietary factors, such as calcium binding to fiber or phytates. Calcium absorption is increased when a calcium deficiency is present or when a patient is on a low-calcium diet. In patients with achlorhydria or hypochlorhydria, calcium absorption, especially with the carbonate salt, may be reduced. /Calcium supplements/
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006., p. 742
Elimination: Renal (20%) - The amount excreted in the urine varies with degree of calcium absorption and whether there is excessive bone loss or failure of renal conservation. Fecal (80%) - Consists mainly of nonabsorbed calcium, with only a small amount of endogenous fecal calcium excreted. /Calcium supplements/
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006., p. 742
Calcium gluconate does not require hepatic metabolism for the release of Ca++ and is as effective as calcium chloride in treating ionic hypocalcemia in the absence of hepatic function.
Calcium is essential for the functional integrity of the nervous, muscular, and skeletal systems. It plays a role in normal cardiac function, renal function, respiration, blood coagulation, and cell membrane and capillary permeability. Also, calcium helps to regulate the release and storage of neurotransmitters and hormones, the uptake and binding of amino acids, absorption of vitamin B 12, and gastrin secretion. The major fraction (99%) of calcium is in the skeletal structure primarily as hydroxyapatite, Ca 10(PO 4) 6(OH) 2; small amounts of calcium carbonate and amorphous calcium phosphates are also present. The calcium of bone is in a constant exchange with the calcium of plasma. Since the metabolic functions of calcium are essential for life, when there is a disturbance in the calcium balance because of dietary deficiency or other causes, the stores of calcium in bone may be depleted to fill the body's more acute needs. Therefore, on a chronic basis, normal mineralization of bone depends on adequate amounts of total body calcium.
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