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    Technical details about CAS-484-23-1, learn more about the structure, uses, toxicity, action, side effects and more

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    CAS-484-23-1

    Manufacturers/Suppliers

    PharmaCompass

    Farmhispania Group, a leading European CDMO in HPAPI Technologies & High Potency Fermentation.

    One Pharma aims to be one of the leading generic companies in Europe.

    2D Structure
    1. Also known as: 484-23-1, Dihydralazin, Dihydrallazin, Dihydrallazine, Ophthazin, 1,4-dihydrazinophthalazine
    Molecular Formula
    C8H10N6
    Molecular Weight
    190.21  g/mol
    InChI Key
    VQKLRVZQQYVIJW-UHFFFAOYSA-N
    FDA UNII
    PCU411F5L6
    1,4-Dihydrazinophthalazine. An antihypertensive agent with actions and uses similar to those of HYDRALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p354)
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (4-hydrazinylphthalazin-1-yl)hydrazine
    2.1.2 InChI
    InChI=1S/C8H10N6/c9-11-7-5-3-1-2-4-6(5)8(12-10)14-13-7/h1-4H,9-10H2,(H,11,13)(H,12,14)
    2.1.3 InChI Key
    VQKLRVZQQYVIJW-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=CC=C2C(=C1)C(=NN=C2NN)NN
    2.2 Other Identifiers
    2.2.1 UNII
    PCU411F5L6
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Depressan

    2. Dihydralazine Sulfate

    3. Dihydrallazine

    4. Dihydrazinophthalazin

    5. Sulfate, Dihydralazine

    2.3.2 Depositor-Supplied Synonyms

    1. 484-23-1

    2. Dihydralazin

    3. Dihydrallazin

    4. Dihydrallazine

    5. Ophthazin

    6. 1,4-dihydrazinophthalazine

    7. Hypopresol

    8. Nepresolin

    9. Nepressol

    10. Tonolysin

    11. Dihydrazinophthalazine

    12. Nepresol

    13. Cassella 532

    14. (4-hydrazinylphthalazin-1-yl)hydrazine

    15. 1,4-dihydrazinonaphthalazine

    16. C 7441

    17. Nsc 526654

    18. 1,4-phthalazinedione, 2,3-dihydro-, Dihydrazone

    19. Phthalazine, 1,4-dihydrazino-

    20. 2,3-dihydro-1,4-phthalazinedione Dihydrazone

    21. Nsc-526654

    22. Pcu411f5l6

    23. Dihydralazine (inn)

    24. Ncgc00159421-02

    25. Ncgc00159421-03

    26. (1z)-4-hydrazinyl-1-hydrazinylidene-1,2-dihydrophthalazine

    27. Dsstox_cid_2935

    28. Dihydralazine [inn]

    29. Dsstox_rid_76795

    30. Dsstox_gsid_22935

    31. Dihidralazina

    32. Dihydralazinum

    33. Dihydralazine [inn:ban]

    34. Dihydralazinum [inn-latin]

    35. Dihidralazina [inn-spanish]

    36. Cas-484-23-1

    37. Ccris 7576

    38. Einecs 207-605-0

    39. Brn 0183442

    40. 1,4-dihydrazino-phthalazine

    41. Unii-pcu411f5l6

    42. Dihydralazine [mi]

    43. Phthalazine,4-dihydrazino-

    44. 1,4-dihydrazineylphthalazine

    45. 1,4-dihydrazinyl-phthalazine

    46. 5-25-17-00465 (beilstein Handbook Reference)

    47. Chembl35505

    48. Schembl149629

    49. 1,4-bis(hydrazino)phthalazine

    50. Dihydralazine [who-dd]

    51. Dtxsid0022935

    52. Schembl14318435

    53. 1, 2,3-dihydro-, Dihydrazone

    54. Chebi:134841

    55. (4-diazanylphthalazin-1-yl)diazane

    56. Zinc4474539

    57. Tox21_111653

    58. Bdbm50088433

    59. Nsc526654

    60. Akos006276458

    61. Akos025393367

    62. Akos030240650

    63. Tox21_111653_1

    64. (4-hydrazinyl-1-phthalazinyl)hydrazine

    65. Db12945

    66. Gs-0013

    67. Db-002370

    68. Cs-0452869

    69. Ft-0602022

    70. 84d231

    71. D07170

    72. 1,4-dihydrazono-1,2,3,4-tetrahydrophthalazine

    73. A827533

    74. Ae-641/40262237

    75. Q408370

    76. Sr-01000944956

    77. Sr-01000944956-1

    2.4 Create Date
    2005-03-26
    3 Chemical and Physical Properties
    Molecular Weight 190.21 g/mol
    Molecular Formula C8H10N6
    XLogP30.2
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count2
    Exact Mass190.09669434 g/mol
    Monoisotopic Mass190.09669434 g/mol
    Topological Polar Surface Area102 Ų
    Heavy Atom Count14
    Formal Charge0
    Complexity167
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antihypertensive Agents

    Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)

    4.2 ATC Code

    C - Cardiovascular system

    C02 - Antihypertensives

    C02D - Arteriolar smooth muscle, agents acting on

    C02DB - Hydrazinophthalazine derivatives

    C02DB01 - Dihydralazine

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