Please Wait
Applying Filters...
menu
    • menu
    Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

    Virtual Booth

    Contact Supplier

    Jai Radhe Sales is your partner for all your sourcing needs.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    Egis is a Hungarian generic pharma company with 110 years history. Our activities incorporate all areas of the pharma value chain.

    Virtual Booth

    Contact Supplier

    Biophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    Menu

    CAS 68-36-0

    BUILDING BLOCK

    PharmaCompass
    Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: 68-36-0, Bitriben, Chloksil, Chloxil, Chloxyl, Cloxil
    Molecular Formula
    C8H4Cl6
    Molecular Weight
    312.8  g/mol
    InChI Key
    OTEKOJQFKOIXMU-UHFFFAOYSA-N
    FDA UNII
    42CH2735EU
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    1,4-bis(trichloromethyl)benzene
    2.1.2 InChI
    InChI=1S/C8H4Cl6/c9-7(10,11)5-1-2-6(4-3-5)8(12,13)14/h1-4H
    2.1.3 InChI Key
    OTEKOJQFKOIXMU-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=CC(=CC=C1C(Cl)(Cl)Cl)C(Cl)(Cl)Cl
    2.2 Other Identifiers
    2.2.1 UNII
    42CH2735EU
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Chloxyl

    2. Hetol

    3. Hexachloro-4-xylene

    4. Hexachloro-p-xylene

    5. Hexachloroparaxylol

    2.3.2 Depositor-Supplied Synonyms

    1. 68-36-0

    2. Bitriben

    3. Chloksil

    4. Chloxil

    5. Chloxyl

    6. Cloxil

    7. Hexichol

    8. Khloksil

    9. Khloxil

    10. Hetol

    11. Benzene, 1,4-bis(trichloromethyl)-

    12. Hexachloroparaxylol

    13. P-di(trichloromethyl)benzene

    14. P-bis(perchloromethyl)benzene

    15. P-bis(trichloromethyl)benzene

    16. Hexachloroparaxylene

    17. Alpha,alpha,alpha,alpha',alpha',alpha'-hexachloro-p-xylene

    18. 2,2-hexachloro-p-xylene

    19. 1,4-di(trichloromethyl)benzene

    20. Hexachloroxylene

    21. Nsc 41883

    22. .omega.-hexachloro-p-xylene

    23. 42ch2735eu

    24. .alpha.,.alpha.'-hexachloroxylene

    25. 1,4-bis-(trichloromethyl)-benzene

    26. Nsc-41883

    27. .alpha.,.alpha.'-hexachloro-p-xylene

    28. .omega.,.omega.'-hexachloro-p-xylene

    29. Hexachloro-4-xylene

    30. Benzene, 1,4-bis[trichloromethyl]-

    31. .alpha.,.alpha.,.alpha.,.alpha.',.alpha.',.alpha.'-hexachloro-p-xylene

    32. P-xylene, .alpha.,.alpha.,.alpha.,.alpha.',.alpha.',.alpha.'-hexachloro-

    33. Alpha,alpha'-hexachloroxylene

    34. 1,4-bis-trichloromethyl Benzene

    35. Hsdb 5202

    36. P-xylene, Alpha,alpha'-hexachloro-

    37. Einecs 200-686-3

    38. Brn 2051282

    39. Unii-42ch2735eu

    40. Ai3-02587

    41. Dsstox_cid_6366

    42. Dsstox_rid_78105

    43. Dsstox_gsid_26366

    44. 4-05-00-00968 (beilstein Handbook Reference)

    45. Schembl545084

    46. P-xylene,.alpha.'-hexachloro-

    47. Chembl3182002

    48. Dtxsid7026366

    49. 1:4-bis(trichloromethyl)benzene

    50. Benzene,4-bis(trichloromethyl)-

    51. 1,4-bis-(trichloromethyl)benzene

    52. P-xylene, Alpha,alpha,alpha,alpha',alpha',alpha'-hexachloro-

    53. Nsc41883

    54. Zinc1673615

    55. Hexachloroparaxylene [mart.]

    56. Tox21_200257

    57. Mfcd00000791

    58. 1,4-hexachlorodimethyl-benzene

    59. Akos016347403

    60. Cas-68-36-0

    61. Ncgc00248579-01

    62. Ncgc00257811-01

    63. As-75866

    64. P-xylene, .alpha.,.alpha.'-hexachloro-

    65. Db-030690

    66. Ft-0606804

    67. H0064

    68. 1,4-bis(trichloromethyl)benzene [mi]

    69. 1,4-bis(trichloromethyl)benzene [hsdb]

    70. D90791

    71. P-xylene,.alpha.,.alpha.'-hexachloro-

    72. A836117

    73. Q4498147

    74. W-104677

    75. .alpha.,.alpha.,.alpha.',.alpha.',.alpha.'-hexachloro-p-xylene

    76. P-xylene,.alpha.,.alpha.,.alpha.',.alpha.',.alpha.'-hexachloro-

    2.4 Create Date
    2005-03-26
    3 Chemical and Physical Properties
    Molecular Weight 312.8 g/mol
    Molecular Formula C8H4Cl6
    XLogP34.6
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count0
    Rotatable Bond Count0
    Exact Mass311.841466 g/mol
    Monoisotopic Mass309.844416 g/mol
    Topological Polar Surface Area0 Ų
    Heavy Atom Count14
    Formal Charge0
    Complexity161
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Therapeutic Uses

    Anthelmintics; Antiplatyhelmintic Agents

    National Library of Medicine's Medical Subject Headings online file (MeSH, 1999)

    MEDICATION (VET): ANTHELMINTIC. HETOL IS USUALLY 85% CONCN OF DRUG. ... USE: TO KILL LIVER FLUKES IN CATTLE & SHEEP.

    Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 48

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Anthelmintics

    Agents that kill parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal. (See all compounds classified as Anthelmintics.)

    Antiplatyhelmintic Agents

    Agents used to treat cestode, trematode, or other flatworm infestations in man or animals. (See all compounds classified as Antiplatyhelmintic Agents.)

    5.2 Absorption, Distribution and Excretion

    HEXACHLORO-P-XYLENE RESIDUES WERE HIGH IN MILK AFTER ADMIN OF AGRAMED NEU TO CATTLE. HEXACHLORO-P-XYLENE WAS LIPOPHILIC AND STABLE. RESIDUES AVERAGED 10 MG/KG ON 2ND DAY AFTER TREATMENT & 0.1 MG/KG 40 DAYS AFTER TREATMENT.

    KONRAD H ET AL; MONATSH VETERINAERMED 33(18) 704 (1978)