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    Technical details about Cefodizima, learn more about the structure, uses, toxicity, action, side effects and more

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    Cefodizima

    FINISHED DOSAGE FORMULATIONS

    GLOBAL SALES INFORMATION

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    2D Structure
    Also known as: 69739-16-8, Cefodizima, Cefodizimum, Cdzm, Cefodizime disodium, Hr 221
    Molecular Formula
    C20H20N6O7S4
    Molecular Weight
    584.7  g/mol
    InChI Key
    XDZKBRJLTGRPSS-BGZQYGJUSA-N
    FDA UNII
    Z31298J4HQ
    Cefodizime is a third-generation, aminothiazolyl cephalosporin for parenteral use. Cefodizime has broad-spectrum activity and is stable to most beta-lactamases.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
    2.1.2 InChI
    InChI=1S/C20H20N6O7S4/c1-7-10(3-11(27)28)37-20(22-7)36-5-8-4-34-17-13(16(30)26(17)14(8)18(31)32)24-15(29)12(25-33-2)9-6-35-19(21)23-9/h6,13,17H,3-5H2,1-2H3,(H2,21,23)(H,24,29)(H,27,28)(H,31,32)/b25-12-/t13-,17-/m1/s1
    2.1.3 InChI Key
    XDZKBRJLTGRPSS-BGZQYGJUSA-N
    2.1.4 Canonical SMILES
    CC1=C(SC(=N1)SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O)CC(=O)O
    2.1.5 Isomeric SMILES
    CC1=C(SC(=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)SC2)C(=O)O)CC(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    Z31298J4HQ
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Cefodizime Disodium

    2. Cefodizime, Dipotassium Salt, (6r-(6alpha,7beta(z)))-isomer

    3. Cefodizime, Disodium Salt, (6r-(6alpha,7beta(z)))-isomer

    4. Hr 221

    5. Hr-221

    6. Modivid

    2.3.2 Depositor-Supplied Synonyms

    1. 69739-16-8

    2. Cefodizima

    3. Cefodizimum

    4. Cdzm

    5. Cefodizime Disodium

    6. Hr 221

    7. Hr-221

    8. Chebi:63214

    9. Hr 221 [as Sodium]

    10. Thr 221 [as Sodium]

    11. Z31298j4hq

    12. Cefodizime (inn)

    13. (6r,7r)-7-[[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

    14. Modivid

    15. S 77 1221 B [as Sodium]

    16. Thr-221

    17. Cefodizime [inn]

    18. 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid,7-[[(2z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, (6r,7r)-

    19. 7-[[(2e)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

    20. Cefodizime Sodium [jan]

    21. Cefodizime Acid

    22. Thr 221

    23. (6r,7r)-7-(2-(2-amino-4-thiazolyl)glyoxylamido)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid 7(sup 2)-(z)-(o-methyloxime)

    24. Cefodizime [inn:ban]

    25. Cefodizimum [inn-latin]

    26. Cefodizima [inn-spanish]

    27. S 77-1221b

    28. S-77-1221b

    29. S-77-1221-b

    30. Cefodizme

    31. Diezime

    32. Timecef

    33. Neucef

    34. Unii-z31298j4hq

    35. Cef;cdz

    36. Cefodizime [mi]

    37. Ec 700-301-3

    38. Hr-221 [as Sodium]

    39. Cefodizime [who-dd]

    40. Thr-221 [as Sodium]

    41. Hr 221 Free Acid

    42. Hr-221 Free Acid

    43. Thr 221 Free Acid

    44. Thr-221 Free Acid

    45. Schembl151101

    46. Chembl2303613

    47. Dtxsid2022757

    48. S-771221b [as Sodium]

    49. Ex-a1379

    50. Zinc3871933

    51. A0c261

    52. Bdbm50422690

    53. Mfcd00864926

    54. S5235

    55. S 77 1221 B Free Acid

    56. S-77-1221-b Free Acid

    57. Db13470

    58. (6r,7r)-7-(((2z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl)sulfanyl)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid

    59. Hy-108402

    60. Cs-0028575

    61. D07643

    62. J-700161

    63. (6r,7r)-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-7-{[(2z)-1-hydroxy-2-(2-imino-2,3-dihydro-1,3-thiazol-4-yl)-2-(methoxyimino)ethylidene]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

    64. (6r,7r)-7-({(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(methyloxy)imino]acetyl}amino)-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]thio}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

    65. (6r,7r)-7-{[(22z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

    66. 7-{[(22z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-3,4-didehydrocepham-4-carboxylic Acid

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 584.7 g/mol
    Molecular Formula C20H20N6O7S4
    XLogP30.2
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count15
    Rotatable Bond Count10
    Exact Mass584.02763169 g/mol
    Monoisotopic Mass584.02763169 g/mol
    Topological Polar Surface Area305 Ų
    Heavy Atom Count37
    Formal Charge0
    Complexity1030
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count1
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

    4.2 ATC Code

    J - Antiinfectives for systemic use

    J01 - Antibacterials for systemic use

    J01D - Other beta-lactam antibacterials

    J01DD - Third-generation cephalosporins

    J01DD09 - Cefodizime