Please Wait
Applying Filters...
menu
    • menu
    Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

    Virtual Booth

    Contact Supplier

    Aurigene is a global leader in accelerating drug innovation through discovery, development & manufacturing.

    Virtual Booth

    Contact Supplier

    Midas Pharma provides expertise in developing and supplying APIs, finished products, and intermediates.

    Virtual Booth

    Contact Supplier

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    Virtual Booth

    Contact Supplier

    Mission CDMO team brings reliability, resourcefulness, & responsiveness in executing your development project.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2025-01-06

    Virtual Booth

    Contact Supplier

    Menu

    Cefotiam Hydrochloride

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    MARKET PLACE

    REF. STANDARDS & IMPURITIES

    PharmaCompass
    $ API Ref.Price (USD/KG) : 499Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: Cefotiam hydrochloride, 66309-69-1, Dsstox_cid_25538, Dsstox_rid_80940, Dsstox_gsid_45538, (6r,7r)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-[2-(dimethylamino)ethyl]tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride
    Molecular Formula
    C18H24ClN9O4S3
    Molecular Weight
    562.1  g/mol
    InChI Key
    SVSFIELZISOJDT-XRZFDKQNSA-N
    One of the CEPHALOSPORINS that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-[2-(dimethylamino)ethyl]tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride
    2.1.2 InChI
    InChI=1S/C18H23N9O4S3.ClH/c1-25(2)3-4-26-18(22-23-24-26)34-7-9-6-32-15-12(14(29)27(15)13(9)16(30)31)21-11(28)5-10-8-33-17(19)20-10;/h8,12,15H,3-7H2,1-2H3,(H2,19,20)(H,21,28)(H,30,31);1H/t12-,15-;/m1./s1
    2.1.3 InChI Key
    SVSFIELZISOJDT-XRZFDKQNSA-N
    2.1.4 Canonical SMILES
    CN(C)CCN1C(=NN=N1)SCC2=C(N3C(C(C3=O)NC(=O)CC4=CSC(=N4)N)SC2)C(=O)O.Cl
    2.1.5 Isomeric SMILES
    CN(C)CCN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)CC4=CSC(=N4)N)SC2)C(=O)O.Cl
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. Abbott 48999

    2. Abbott-48999

    3. Abbott48999

    4. Cefotiam

    5. Cefotiam Hydrochloride

    6. Ceradolan

    7. Cgp 14221 E

    8. Cgp-14221-e

    9. Cgp14221e

    10. Haloapor

    11. Halospor

    12. Hydrochloride, Cefotiam

    13. Sce 963

    14. Sce-963

    15. Sce963

    2.2.2 Depositor-Supplied Synonyms

    1. Cefotiam Hydrochloride

    2. 66309-69-1

    3. Dsstox_cid_25538

    4. Dsstox_rid_80940

    5. Dsstox_gsid_45538

    6. (6r,7r)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-[2-(dimethylamino)ethyl]tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid;hydrochloride

    7. Cas-66309-69-1

    8. Nsc-758164

    9. Sr-01000841230

    10. Cefotiam Monohydrochloride

    11. Ncgc00016998-01

    12. Schembl65480

    13. Mls002153835

    14. Chembl1200589

    15. Dtxsid40860766

    16. Hms1569b05

    17. Tox21_110730

    18. Akos032960346

    19. Tox21_110730_1

    20. Ccg-220482

    21. Ncgc00179594-03

    22. (6r-trans)-7-[2-(2-aminothiazol-4-yl)acetamido]-3-[[[1-[2-(dimethylamino)ethyl]-1h-tetrazol-5-yl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Hydrochloride

    23. Smr001233198

    24. Sr-01000841230-3

    25. W-104762

    26. Cefotiam Hydrochloride, Antibiotic For Culture Media Use Only

    27. 1428118-46-0

    28. 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid,7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1h-tetrazol-5-yl]thio]methyl]-8-oxo-, Dihydrochloride, (6r,7r)-

    2.3 Create Date
    2007-12-05
    3 Chemical and Physical Properties
    Molecular Weight 562.1 g/mol
    Molecular Formula C18H24ClN9O4S3
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count13
    Rotatable Bond Count10
    Exact Mass561.0801915 g/mol
    Monoisotopic Mass561.0801915 g/mol
    Topological Polar Surface Area251 Ų
    Heavy Atom Count35
    Formal Charge0
    Complexity848
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)