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    Cefoxitin Sodium

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    GLOBAL SALES INFORMATION

    MARKET PLACE

    REF. STANDARDS & IMPURITIES

    PharmaCompass
    $ API Ref.Price (USD/KG) : 441Xls

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    2D Structure
    Also known as: Cefoxitin sodium salt, 33564-30-6, Betacef, Cenomycin, Mefoxin, Merxin
    Molecular Formula
    C16H16N3NaO7S2
    Molecular Weight
    449.4  g/mol
    InChI Key
    GNWUOVJNSFPWDD-XMZRARIVSA-M
    FDA UNII
    Q68050H03T
    A semisynthetic cephamycin antibiotic resistant to beta-lactamase.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;(6R,7S)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
    2.1.2 InChI
    InChI=1S/C16H17N3O7S2.Na/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19;/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22);/q;+1/p-1/t14-,16+;/m1./s1
    2.1.3 InChI Key
    GNWUOVJNSFPWDD-XMZRARIVSA-M
    2.1.4 Canonical SMILES
    COC1(C2N(C1=O)C(=C(CS2)COC(=O)N)C(=O)[O-])NC(=O)CC3=CC=CS3.[Na+]
    2.1.5 Isomeric SMILES
    CO[C@@]1([C@@H]2N(C1=O)C(=C(CS2)COC(=O)N)C(=O)[O-])NC(=O)CC3=CC=CS3.[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    Q68050H03T
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Cefoxitin

    2. Mfoxin

    3. Mefoxin

    4. Mefoxitin

    5. Mk 306

    6. Mk-306

    7. Mk306

    8. Sodium, Cefoxitin

    2.3.2 Depositor-Supplied Synonyms

    1. Cefoxitin Sodium Salt

    2. 33564-30-6

    3. Betacef

    4. Cenomycin

    5. Mefoxin

    6. Merxin

    7. Cefoxitin (sodium)

    8. Mefoxitin

    9. Mls000028557

    10. Chebi:3501

    11. Q68050h03t

    12. Smr000058809

    13. Monosodium Cefoxitin

    14. Sodium (6r,7s)-3-(hydroxymethyl)-7-methoxy-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate Carbamate (ester)

    15. Cefoxil

    16. Cefoxotin Sodium

    17. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 3-(((aminocarbonyl)oxy)methyl)-7-methoxy-8-oxo-7-((2-thienylacetyl)amino)-, Sodium Salt, (6r-cis)-

    18. Ncgc00183034-01

    19. Mk-306

    20. Unii-q68050h03t

    21. Prestwick_12

    22. Mefoxin In Plastic Container

    23. Sodium (6r,7s)-3-((carbamoyloxy)methyl)-7-methoxy-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

    24. Sodium (6r,7s)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

    25. Einecs 251-574-6

    26. Mefoxin (tn)

    27. Cas-33564-30-6

    28. Mfcd00079042

    29. Mk 206

    30. Cefoxitin Na

    31. Cefoxitin Sodium [usan:usp:ban:jan]

    32. Cefoxitin And Dextrose In Duplex Container

    33. Opera_id_912

    34. Cefoxitin (sodium Salt)

    35. Sodium;(6r,7s)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

    36. Dsstox_cid_28921

    37. Dsstox_rid_83187

    38. Dsstox_gsid_48995

    39. Schembl41178

    40. Cefoxitin Sodium (jan/usp)

    41. Mefoxin In Dextrose 5% In Plastic Container

    42. Mls001076334

    43. Mls002222151

    44. Bidd:gt0505

    45. Spectrum1502031

    46. L 620388

    47. Cefoxitin Sodium [jan]

    48. Cefoxitin Sodium [usan]

    49. Cefoxitin Sodium [vandf]

    50. Chembl1200530

    51. Dtxsid8048995

    52. Cefoxitin For Peak Identification

    53. Hms501m18

    54. Cefoxitin Sodium [mart.]

    55. Cefoxitin Sodium [who-dd]

    56. Hms1570h05

    57. Hms1921f14

    58. Hms2092p11

    59. Hms2097h05

    60. Hms2232e15

    61. Hms3259k10

    62. Hms3714h05

    63. Mefoxin In Sodium Chloride 0.9% In Plastic Container

    64. Cefoxitin Sodium Salt [mi]

    65. Bcp12069

    66. Hy-b1117

    67. Tox21_113485

    68. Ccg-39693

    69. Akos024464829

    70. Cefoxitin Sodium [orange Book]

    71. Ac-1303

    72. Cefoxitin Sodium [usp Impurity]

    73. Cs-4716

    74. Nc00556

    75. Cefoxitin Sodium [usp Monograph]

    76. As-56725

    77. Sodium (6r-cis)-3-((carbamoyloxy)methyl)-7-methoxy-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate

    78. C3602

    79. C-2480

    80. C08106

    81. D00913

    82. A821839

    83. (r)-4-isopropyl-5,5-diphenyl-2-oxazolidinone

    84. Q27106110

    85. Cefoxitin Sodium Salt, Antibiotic For Culture Media Use Only

    86. (6r,7s)-3-[[(aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[420]oct-2-ene-2-carboxylic Acid Sodium Salt

    87. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 3-(((aminocarbonyl)oxy)methyl)-7-methoxy-8-oxo-7-((2-thienylacetyl)amino)-, Monosodium Salt, (6r-cis)-

    88. Sodium (6r,7s)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

    2.4 Create Date
    2008-02-05
    3 Chemical and Physical Properties
    Molecular Weight 449.4 g/mol
    Molecular Formula C16H16N3NaO7S2
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count9
    Rotatable Bond Count8
    Exact Mass449.03273649 g/mol
    Monoisotopic Mass449.03273649 g/mol
    Topological Polar Surface Area205 Ų
    Heavy Atom Count29
    Formal Charge0
    Complexity750
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 4  
    Drug NameCefoxitin and dextrose in duplex container
    Active IngredientCefoxitin sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 2gm base/vial; eq 1gm base/vial
    Market StatusPrescription
    CompanyB Braun

    2 of 4  
    Drug NameMefoxin in plastic container
    Active IngredientCefoxitin sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 40mg base/ml; eq 20mg base/ml
    Market StatusPrescription
    CompanyMylan Institutional

    3 of 4  
    Drug NameCefoxitin and dextrose in duplex container
    Active IngredientCefoxitin sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 2gm base/vial; eq 1gm base/vial
    Market StatusPrescription
    CompanyB Braun

    4 of 4  
    Drug NameMefoxin in plastic container
    Active IngredientCefoxitin sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 40mg base/ml; eq 20mg base/ml
    Market StatusPrescription
    CompanyMylan Institutional

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Cephalosporins [CS]; Cephalosporin Antibacterial [EPC]