1. 104-29-0
2. 3-(4-chlorophenoxy)-1,2-propanediol
3. 3-(4-chlorophenoxy)propane-1,2-diol
4. Chlorophenesin
5. Adermykon
6. Gecophen
7. Demykon
8. Mycil
9. Chlorphenesinum
10. P-chlorophenyl Glyceryl Ether
11. Chlorphenesine
12. Clorfenesina
13. 1,2-propanediol, 3-(4-chlorophenoxy)-
14. 3-(p-chlorophenoxy)-1,2-propanediol
15. Clorfenesina [inn-spanish]
16. Chlorphenesine [inn-french]
17. Chlorphenesinum [inn-latin]
18. Glycerol Alpha-p-chlorophenyl Ether
19. P-chlorophenyl-alpha-glyceryl Ether
20. 3-(p-chlorophenoxy)propane-1,2-diol
21. Nsc 6401
22. 1,2-propanediol, 3-(p-chlorophenoxy)-
23. I670dal4sz
24. Chebi:3642
25. 2-chlorphenesin
26. Nsc-6401
27. Mfcd00021990
28. Glycerol .alpha.-p-chlorophenyl Ether
29. P-chlorophenyl-.alpha.-glyceryl Ether
30. Ncgc00160584-01
31. 1,2-propanediol, 3-(4-chlorophenoxy)- (9ci)
32. Gechophen
33. P-chlorophenyl
34. Chlorphenesin [inn:ban]
35. 3-(4-chlorophenoxy)propane-1,2-diol;3-(4-chlorophenoxy)propane-1,2-diol
36. Alpha-glyceryl Ether
37. Einecs 203-192-6
38. Unii-i670dal4sz
39. Brn 2210845
40. Ai3-24623
41. (+/-)-chlorphenesin
42. Maybridge1_000170
43. Chlorphenesin [mi]
44. Wln: Q1yq1or Dg
45. Chlorphenesin [inn]
46. Mixcom1_000324
47. 1, 3-(p-chlorophenoxy)-
48. Chlorphenesin [inci]
49. Dsstox_cid_28954
50. Dsstox_rid_83219
51. Dsstox_gsid_49028
52. Oprea1_755443
53. Schembl93836
54. Chlorphenesin [vandf]
55. 1, 3-(4-chlorophenoxy)-
56. 4-06-00-00831 (beilstein Handbook Reference)
57. Chlorphenesin [mart.]
58. Chlorphenesin [who-dd]
59. Chembl388751
60. Dtxsid0049028
61. Nsc6401
62. Hms3604n15
63. 3-p-chlorophenoxy-1,2-propanediol
64. Albb-025796
65. Hy-a0133
66. Tox21_113554
67. 4-amino-4-chlorobenzophenone
68. Ac-266
69. S6442
70. 1-(p-chlorophenoxy)-2,3-propanediol
71. Akos005203039
72. Db00856
73. Hs-0080
74. 3-(p-chlorophenoxy)-propane-1,2 Diol
75. Chlorphenesin 100 Microg/ml In Methanol
76. Bp-20218
77. Cas-104-29-0
78. Sy058281
79. C3659
80. Chlorphenesin 100 Microg/ml In Acetonitrile
81. Cs-0017448
82. Ft-0623711
83. C07928
84. D71194
85. Sr-01000944964
86. J-001139
87. Q5103226
88. Sr-01000944964-1
89. Z1348239594
| Molecular Weight | 202.63 g/mol |
|---|---|
| Molecular Formula | C9H11ClO3 |
| XLogP3 | 1.2 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 4 |
| Exact Mass | 202.0396719 g/mol |
| Monoisotopic Mass | 202.0396719 g/mol |
| Topological Polar Surface Area | 49.7 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 135 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Used, along with rest and physical therapy, to treat injuries and other painful muscular conditions. Investigated for use in trigeminal neuralgia (tic douloureux), a neuropathic disorder characterized by severe facial pain. Was investigated as a modulator of histamine release.
Chlorphenesin is a muscle relaxant. It blocks nerve impulses (or pain sensations) that are sent to the brain.
Muscle Relaxants, Central
A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358) (See all compounds classified as Muscle Relaxants, Central.)
D - Dermatologicals
D01 - Antifungals for dermatological use
D01A - Antifungals for topical use
D01AE - Other antifungals for topical use
D01AE07 - Chlorphenesin
Absorption
Rapid and complete.
Hepatic. 85% of a dose excreted within 24 hours as the glucuronide metabolite.
2.3-5 hours
The mechanism of action of chlorphenesin is not well defined, and its effects are measured mainly by subjective responses. It is known that chlorphenesin acts in the central nervous system (CNS) rather than directly on skeletal muscle.
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