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    Ciprofibrate

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    DIGITAL CONTENT

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    2D Structure
    Also known as: 52214-84-3, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid, Lipanor, Ciprofibratum, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid, Ciprofibrato
    Molecular Formula
    C13H14Cl2O3
    Molecular Weight
    289.15  g/mol
    InChI Key
    KPSRODZRAIWAKH-UHFFFAOYSA-N
    FDA UNII
    F8252JGO9S
    Ciprofibrate is a fibrate derivative with antilipidemic activity.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
    2.1.2 InChI
    InChI=1S/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)
    2.1.3 InChI Key
    KPSRODZRAIWAKH-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(C)(C(=O)O)OC1=CC=C(C=C1)C2CC2(Cl)Cl
    2.2 Other Identifiers
    2.2.1 UNII
    F8252JGO9S
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Hyperlipen

    2. Lipanor

    3. Modalim

    4. Oroxadin

    5. Win 35,833

    2.3.2 Depositor-Supplied Synonyms

    1. 52214-84-3

    2. 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropanoic Acid

    3. Lipanor

    4. Ciprofibratum

    5. 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic Acid

    6. Ciprofibrato

    7. Modalim

    8. Win 35833

    9. Win-35833

    10. Propanoic Acid, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl-

    11. Mfcd00467135

    12. 2-(p-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropionic Acid

    13. Nsc-759617

    14. F8252jgo9s

    15. Chebi:50867

    16. Propanoic Acid, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-

    17. Ncgc00164447-01

    18. 2-{[4-(2,2-dichlorocyclopropyl)phenyl]oxy}-2-methylpropanoic Acid

    19. Dsstox_cid_331

    20. Dsstox_rid_75519

    21. Dsstox_gsid_20331

    22. Ciprofibratum [inn-latin]

    23. Ciprofibrato [inn-spanish]

    24. Hiperlipen

    25. Ciprol

    26. Smr000857190

    27. Ccris 173

    28. Sr-01000075734

    29. Einecs 257-744-6

    30. Ciprofibrate (usan/inn)

    31. Brn 1984981

    32. Unii-f8252jgo9s

    33. 2-[p-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropionic Acid

    34. Ciprofibrate?

    35. Ciprofibrate [usan:inn:ban]

    36. 2-(4-(2,2-dichlorocyclopropyl)phenoxy)2-methylpropanoic Acid

    37. 2-[p-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic Acid

    38. Cas-52214-84-3

    39. Ciprofibrate- Bio-x

    40. Prestwick0_001076

    41. Prestwick1_001076

    42. Prestwick2_001076

    43. Prestwick3_001076

    44. Ciprofibrate [mi]

    45. Ciprofibrate [inn]

    46. C 0330

    47. Ciprofibrate [usan]

    48. Lopac0_000168

    49. Schembl26870

    50. Bspbio_001092

    51. Ciprofibrate [mart.]

    52. Mls002154143

    53. Mls006011758

    54. Ciprofibrate [who-dd]

    55. Win35833

    56. Spbio_002996

    57. Bpbio1_001202

    58. Chembl557555

    59. Gtpl3438

    60. Dtxsid8020331

    61. Bcpp000277

    62. Ciprofibrate [ep Impurity]

    63. Ciprofibrate For System Suitability

    64. Hms1571g14

    65. Hms2098g14

    66. Hms2235j14

    67. Hms3260b17

    68. Hms3369b22

    69. Hms3656p09

    70. Hms3715g14

    71. Pharmakon1600-01502008

    72. Ciprofibrate [ep Monograph]

    73. Bcp03728

    74. Hy-b0664

    75. Tox21_112121

    76. Tox21_201359

    77. Tox21_302840

    78. Tox21_500168

    79. Bbl010821

    80. Bdbm50371235

    81. Nsc759617

    82. S2665

    83. Stk624758

    84. Akos005557843

    85. Tox21_112121_1

    86. Ac-1018

    87. Bcp9000533

    88. Ccg-204263

    89. Db09064

    90. Ks-1201

    91. Lp00168

    92. Nsc 759617

    93. Sdccgsbi-0050156.p002

    94. Ncgc00015202-02

    95. Ncgc00015202-03

    96. Ncgc00015202-04

    97. Ncgc00015202-05

    98. Ncgc00015202-06

    99. Ncgc00015202-08

    100. Ncgc00015202-20

    101. Ncgc00015202-21

    102. Ncgc00093652-01

    103. Ncgc00093652-02

    104. Ncgc00256361-01

    105. Ncgc00258911-01

    106. Ncgc00260853-01

    107. Bd164311

    108. Bcp0726000148

    109. Ab00514032

    110. Eu-0100168

    111. Ft-0602946

    112. Sw197242-4

    113. D03521

    114. O10468

    115. Ab00514032_06

    116. 214c843

    117. A828985

    118. J-520054

    119. Q3496452

    120. Sr-01000075734-1

    121. Sr-01000075734-4

    122. Sr-01000075734-7

    123. Brd-a49358627-001-03-9

    124. Brd-a49358627-001-10-4

    125. 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropionic Acid

    126. Ciprofibrate, European Pharmacopoeia (ep) Reference Standard

    127. 2-[4-[2,2-bis(chloranyl)cyclopropyl]phenoxy]-2-methyl-propanoic Acid

    128. Ciprofibrate For System Suitability, European Pharmacopoeia (ep) Reference Standard

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 289.15 g/mol
    Molecular Formula C13H14Cl2O3
    XLogP33.4
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count4
    Exact Mass288.0319997 g/mol
    Monoisotopic Mass288.0319997 g/mol
    Topological Polar Surface Area46.5 Ų
    Heavy Atom Count18
    Formal Charge0
    Complexity333
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Peroxisome Proliferators

    A class of nongenotoxic CARCINOGENS that induce the production of hepatic PEROXISOMES and induce hepatic neoplasms after long-term administration. (See all compounds classified as Peroxisome Proliferators.)

    Hypolipidemic Agents

    Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS. (See all compounds classified as Hypolipidemic Agents.)

    4.2 ATC Code

    C10AB08

    S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

    C - Cardiovascular system

    C10 - Lipid modifying agents

    C10A - Lipid modifying agents, plain

    C10AB - Fibrates

    C10AB08 - Ciprofibrate