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2D Structure
Also known as: Oxocopper, Copper oxide (cuo), Copper monoxide, Banacobru ol, Chrome brown, Copper brown
Molecular Formula
CuO
Molecular Weight
79.55  g/mol
InChI Key
QPLDLSVMHZLSFG-UHFFFAOYSA-N

1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
oxocopper
2.1.2 InChI
InChI=1S/Cu.O
2.1.3 InChI Key
QPLDLSVMHZLSFG-UHFFFAOYSA-N
2.1.4 Canonical SMILES
O=[Cu]
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Copper Dioxide (cuo2)

2. Copper Oxide (cuo)

3. Cupric Oxide

2.2.2 Depositor-Supplied Synonyms

1. Oxocopper

2. Copper Oxide (cuo)

3. Copper Monoxide

4. Banacobru Ol

5. Chrome Brown

6. Copper Brown

7. Copper Monooxide

8. Copper(2+) Oxide

9. C.i. Pigment Black 15

10. Copper (ii) Oxide

11. Cu-o Linkage

12. C.i. 77403

13. Mfcd00010979

14. Cuo

15. Paramelaconite

16. Copacaps

17. Copporal

18. Natural Tenorite

19. Wolmanac Concentrate

20. Boliden Salt K-33

21. Caswell No. 265

22. Ci Pigment Black 15

23. Boliden-cca Wood Preservative

24. Cca Type C Wood Preservative

25. Hsdb 266

26. Osmose K-33 Wood Preservative

27. Osmose P-50 Wood Preservative

28. Osmose K-33-a Wood Preservative

29. Osmose K-33-c Wood Preservative

30. Einecs 215-269-1

31. Nsc 83537

32. Epa Pesticide Chemical Code 042401

33. Unii-v1xjq704r4

34. Ci 77403

35. Copper-oxygen

36. Farboil Super Tropical Anti-fouling 1260

37. Copper(ii)oxide

38. Copper Ii Oxide

39. Copper Oxide Ink

40. Copper Oxide, Cuo

41. Copper Oxide Powder

42. Copper-(ii) Oxide

43. Copper Oxide Dispersion

44. Copper Oxide Nanopowder

45. Cupric Oxide Nanopowder

46. Copper Oxide Nano-chains

47. Copper(ii) Oxide, Cp

48. Copper Oxide Nanoparticles

49. Copper(ii) Oxide, Powder

50. Ec 215-269-1

51. Copper(ii) Oxide, Puratronic?

52. Copper Oxide Powder, 99+% Nano

53. Nsc83537

54. Copper(ii) Oxide, Lr, >=97%

55. Copper Oxide Nanoparticles Dispersion

56. Akos015950660

57. Copper(ii) Oxide (99.995%-cu)

58. Copper Oxide Nanoparticles / Nanopowder

59. Copper(ii) Oxide, Acs Reagent, >=99.0%

60. Copper(ii) Oxide, Powder, <10 Mum, 98%

61. Cs-0016015

62. Ft-0624050

63. Chromium Silicide (crsi2) Sputtering Targets

64. Copper(ii) Oxide, >=99.0% (rt), Granular

65. Copper(ii) Oxide, 99.999% Trace Metals Basis

66. Copper(ii) Oxide, P.a., Acs Reagent, 99.0%

67. J-520121

68. Q27458610

69. Copper(ii) Oxide, Powder, 99.99% Trace Metals Basis

70. Copper(ii) Oxide, Powder, 99.995% Trace Metals Basis

71. Copper(ii) Oxide, Nanopowder, <50 Nm Particle Size (tem)

72. Copper(ii) Oxide, Puriss. P.a., >=99.0% (rt), Powder

73. Copper(ii) Oxide, Nanotubes, Diam. X L 10-12 Nm X 75-100 Nm

74. Copper(ii) Oxide, Needles, Mixture Of Cuo And Cu2o, Acs Reagent

75. Pedot Pss Poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate )

76. Copper(ii) Oxide On Alumina, 14-20 Mesh, Extent Of Labeling: 13 Wt. % Loading

2.3 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 79.55 g/mol
Molecular Formula CuO
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass78.924512 g/mol
Monoisotopic Mass78.924512 g/mol
Topological Polar Surface Area17.1 Ų
Heavy Atom Count2
Formal Charge0
Complexity2
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Trace Elements

A group of chemical elements that are needed in minute quantities for the proper growth, development, and physiology of an organism. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) (See all compounds classified as Trace Elements.)


4.2 Absorption, Distribution and Excretion

The pulmonary uptake of copper oxide /occurred/ in rats exposed to aerosols containing 50-80 mg/cu m. Animals were exposed for 15, 30, 45, or 60 minutes and killed immediately. Another group was exposed for 180 minutes and killed at 0, 3, 6, 12, 18, or 24 hours after exposure. Electron microscopic histologic examination showed that absorption of copper had occurred in animals exposed for 180 minutes. Copper oxide particles penetrated the epithelial cells of alveoli and were found in plasma 6 hours after exposure began. Copper oxide was also observed in the proximal convoluted tubules of the kidney. /Copper oxide/

USEPA; Drinking Water Criteria Document for Copper (Final Draft) p.III-3 (1985) EPA-600/X-84-190-1


VET: COPPER SOURCE. 80% COPPER CONTENT. LOW ABSORPTION RATE & HIGH FECAL EXCRETION RATE IN CATTLE & SWINE FEEDING TRIALS. IN GENERAL MONOGASTRIC ANIMALS UTILIZE /CUPRIC OXIDE/ BETTER THAN RUMINANTS. POULTRY UTILIZATION IS SOMEWHERE BETWEEN THE TWO.

Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 135


Cheviot ewes (mean live weight 50 kg) were given single doses of 0, 2.5, 5, 10, or 20 g cupric oxide particles in gelatin capsules while receiving a diet of marginal copper content based on pelleted oats. After 65 days, liver copper concentrations had increased curvilinearly in relation to dose and all ewes given 10 or 20 g cupric oxide particles showed increases of at least 13.4 mmol/kg dry matter (850 ppm). Liver copper concentrations had generally declined after 85 days but biochemical and histological evidence of copper toxicity was recorded in one ewe which had received 20 g cupric oxide particles. Despite marked variations between individual sheep, a dose of 0.1 g/kg liveweight (5 g) was considered to be safe and did not induce clinical copper toxicity in five sheep of the susceptible North Ronaldsay breed given the same basal diet.

PMID:3589168 Suttle NF; Res Vet Sci 42 (2): 219-23 (1987)


Crossbred steers, mean initial live weight 220 kg, were given a diet of barley and hay ad libitum. Each animal received a single oral does of 0, 5, 10, 20, or 40 g cupric oxide particles. A dose of 5 g cupric oxide particles increased liver copper stores for about 240 days and higher doses increased liver stores for longer but 40 g was no more effective than 20 g (85 mg/kg live weight). Variation among individuals was marked but the highest liver copper concentration recorded (7.59 mmol/kg dry matter) produced no biochemical evidence of copper toxicity. Cupric oxide particles were separated into three fractions, clumps, short rods and long; and 5 mg/kg live weight of each fraction given to steers of 173 kg mean live weight. The form of the particles did not affect either their retention in the alimentary tract or the accumulation of copper in the liver.

PMID:3589169 Suttle NF; Res Vet Sci 42 (2): 224-7 (1987)


For more Absorption, Distribution and Excretion (Complete) data for COPPER(II) OXIDE (6 total), please visit the HSDB record page.