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1. 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine
1. 675126-05-3
2. (1r,4s)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine
3. (1r,4s)-trans-norsertraline
4. Norsertraline, (1r,4s)-trans-
5. Sep-225289
6. 4d28ey0l5t
7. Dasotraline [usan:inn]
8. Unii-4d28ey0l5t
9. Dasotraline [inn]
10. Dasotraline (usan/inn)
11. Dasotraline [usan]
12. Dasotraline [who-dd]
13. Schembl263142
14. Dasotraline(sep-225289)
15. Dasotraline; Sep 225289
16. Gtpl8308
17. Chembl3301595
18. Dtxsid20217855
19. Bcp24754
20. Ex-a2622
21. Zinc2510873
22. Dasotraline(sep-225289) Free Base
23. Db12305
24. Sep-225,289
25. Ac-36184
26. Hy-12850
27. Cs-0012724
28. D10700
29. A857937
30. Q27076989
31. (1r,4s)-4-(3,4-dichloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-ylamine
32. 4beta-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalene-1alpha-amine
33. 1-naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-, (1r,4s)-
Molecular Weight | 292.2 g/mol |
---|---|
Molecular Formula | C16H15Cl2N |
XLogP3 | 4.3 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 1 |
Rotatable Bond Count | 1 |
Exact Mass | 291.0581549 g/mol |
Monoisotopic Mass | 291.0581549 g/mol |
Topological Polar Surface Area | 26 Ų |
Heavy Atom Count | 19 |
Formal Charge | 0 |
Complexity | 309 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 2 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
Dasotraline has been shown in preclinical studies to be a potent and balanced reuptake inhibitor of serotonin, norepinephrine and dopamine (SNDRI). Serotonin, norepinephrine and dopamine are neurotransmitters associated with depression. There are currently no marketed treatments for depression that inhibit reuptake of all three neurotransmitters.