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    Dihydralazine Sulfate

    ACTIVE PHARMA INGREDIENTS

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    2D Structure
    Also known as: 7327-87-9, Dihydralazine sulphate, Depressan, 1,4-dihydrazinophthalazine sulfate, Hydralazine sulfate, 1,4-dihydrazinylphthalazine sulfate
    Molecular Formula
    C8H12N6O4S
    Molecular Weight
    288.29  g/mol
    InChI Key
    BWHAMWGGORIDBK-UHFFFAOYSA-N
    FDA UNII
    1C2B1W91NK
    1,4-Dihydrazinophthalazine. An antihypertensive agent with actions and uses similar to those of HYDRALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p354)
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (4-hydrazinylphthalazin-1-yl)hydrazine;sulfuric acid
    2.1.2 InChI
    InChI=1S/C8H10N6.H2O4S/c9-11-7-5-3-1-2-4-6(5)8(12-10)14-13-7;1-5(2,3)4/h1-4H,9-10H2,(H,11,13)(H,12,14);(H2,1,2,3,4)
    2.1.3 InChI Key
    BWHAMWGGORIDBK-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=CC=C2C(=C1)C(=NN=C2NN)NN.OS(=O)(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    1C2B1W91NK
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Depressan

    2. Dihydralazine

    3. Dihydrallazine

    4. Dihydrazinophthalazin

    5. Sulfate, Dihydralazine

    2.3.2 Depositor-Supplied Synonyms

    1. 7327-87-9

    2. Dihydralazine Sulphate

    3. Depressan

    4. 1,4-dihydrazinophthalazine Sulfate

    5. Hydralazine Sulfate

    6. 1,4-dihydrazinylphthalazine Sulfate

    7. Nepresol

    8. Ophthazin

    9. 1,4-dihydrazinophthalazine Hydrogen Sulfate

    10. (4-hydrazinylphthalazin-1-yl)hydrazine;sulfuric Acid

    11. 1c2b1w91nk

    12. Ophthazin Sulfate

    13. Ccris 5386

    14. Sulfate De Dihydralazine [french]

    15. Sulfate De Dihydralazine

    16. Einecs 230-808-0

    17. Unii-1c2b1w91nk

    18. Dihydralazinsulfat

    19. Phthalazine, 1,4-dihydrazino-, Sulfate (1:1)

    20. Nepresol (tn)

    21. Dihydralazine Sulfate,(s)

    22. Dihydralazine Hydrogen Sulfate

    23. Schembl1374523

    24. Chembl2106266

    25. Dtxsid10223501

    26. Dihydralazine Sulfate [mi]

    27. Bcp11859

    28. Dihydralazine For System Suitability

    29. Hy-n7065

    30. Mfcd00035271

    31. S5030

    32. Dihydralazine Sulfate [mart.]

    33. Akos015960760

    34. Akos037643215

    35. Dihydralazine Sulfate [who-dd]

    36. Ccg-267357

    37. Cs-w012211

    38. Sb67406

    39. Ac-12152

    40. As-10957

    41. Ft-0731572

    42. (4-hydrazinylphthalazin-1-yl)hydrazine Sulfate

    43. C76337

    44. D07830

    45. 327d879

    46. A920291

    47. 1,4-dihydrazinophthalazine Hydrogen Sulphate

    48. W-104459

    49. Q27252218

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 288.29 g/mol
    Molecular Formula C8H12N6O4S
    Hydrogen Bond Donor Count6
    Hydrogen Bond Acceptor Count10
    Rotatable Bond Count2
    Exact Mass288.06407406 g/mol
    Monoisotopic Mass288.06407406 g/mol
    Topological Polar Surface Area185 Ų
    Heavy Atom Count19
    Formal Charge0
    Complexity248
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antihypertensive Agents

    Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)