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2D Structure
Also known as: 110-97-4, Bis(2-hydroxypropyl)amine, 1,1'-iminodipropan-2-ol, Bis(2-propanol)amine, 1,1'-iminodi-2-propanol, 2-propanol, 1,1'-iminobis-
Molecular Formula
C6H15NO2
Molecular Weight
133.19  g/mol
InChI Key
LVTYICIALWPMFW-UHFFFAOYSA-N
FDA UNII
0W44HYL8T5

1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-(2-hydroxypropylamino)propan-2-ol
2.1.2 InChI
InChI=1S/C6H15NO2/c1-5(8)3-7-4-6(2)9/h5-9H,3-4H2,1-2H3
2.1.3 InChI Key
LVTYICIALWPMFW-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(CNCC(C)O)O
2.2 Other Identifiers
2.2.1 UNII
0W44HYL8T5
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Bis(2-hydroxypropyl)amine

2. Diisopropanolamine Hydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 110-97-4

2. Bis(2-hydroxypropyl)amine

3. 1,1'-iminodipropan-2-ol

4. Bis(2-propanol)amine

5. 1,1'-iminodi-2-propanol

6. 2-propanol, 1,1'-iminobis-

7. Di-2-propanolamine

8. Di-isopropanolamine

9. Dipa (alcohol)

10. Dipropyl-2,2'-dihydroxy-amine

11. 1-(2-hydroxypropylamino)propan-2-ol

12. N,n-bis(2-hydroxypropyl)amine

13. 1,1'-iminobis-2-propanol

14. 2-propanol, 1,1'-iminodi-

15. Diisopropanolamin

16. 1-[(2-hydroxypropyl)amino]propan-2-ol

17. Nsc 4963

18. Nsc-4963

19. 1,1'-iminobis[2-propanol]

20. 0w44hyl8t5

21. Dsstox_cid_179

22. Dsstox_rid_75418

23. Dsstox_gsid_20179

24. 1335-54-2

25. 1,1'-iminobis(2-propanol)

26. 1,1'-azanediylbis(propan-2-ol)

27. Cas-110-97-4

28. Ccris 6234

29. Hsdb 338

30. Einecs 203-820-9

31. Di-isopropanol Amine

32. Brn 0605363

33. Unii-0w44hyl8t5

34. 2-propanol,1,1'-iminobis-

35. Dipa Alcohol

36. Diiso-propanolamine

37. Diisopropanol Amine

38. Mfcd00004531

39. Di(2-hydroxypropyl)amine

40. 2-propanol,1'-iminodi-

41. 2-propanol,1'-iminobis-

42. Bis-(2-hydroxypropyl)amine

43. Ec 203-820-9

44. Bis-(2-hydroxypropyl)-amine

45. Schembl22774

46. 3-04-00-00761 (beilstein Handbook Reference)

47. 1,1'-azanediyldipropan-2-ol

48. Di(2-hydroxy-n-propyl) Amine

49. Diisopropanolamine [ii]

50. Diisopropanolamine [mi]

51. 1,1'-imino-di(2-propanol)

52. Chembl2106303

53. Dtxsid8020179

54. 1,1'-azanediylbis Propan-2-ol

55. Diisopropanolamine [hsdb]

56. Diisopropanolamine [inci]

57. 1,1'-azanediyldi(propan-2-ol)

58. Diisopropanolamine [vandf]

59. Nsc4963

60. Chebi:143266

61. Wln: Qy1 & 1m1yq1

62. Diisopropanolamine [mart.]

63. Albb-005923

64. Amy25531

65. Tox21_201602

66. Tox21_302859

67. 2-propanol, 1,1'-iminobis-, N-(hydrogenated Tallow Alkyl) Derivs.

68. Bbl013266

69. Stk503623

70. Akos005457854

71. Dipa Low Freeze Grade 85 (salt/mix)

72. Dipa Low Freeze Grade 90 (salt/mix)

73. Ncgc00249081-01

74. Ncgc00256476-01

75. Ncgc00259151-01

76. 68153-96-8

77. Vs-03726

78. Diisopropanolamine (dl- And Meso- Mixture)

79. Bis(2-hydroxypropyl)amine, >=98.0% (t)

80. D0924

81. Q777543

82. J-660021

83. F0001-0230

84. 9afd2c98-2177-4499-8eb2-1c8ea079f21d

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 133.19 g/mol
Molecular Formula C6H15NO2
XLogP3-0.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass133.110278721 g/mol
Monoisotopic Mass133.110278721 g/mol
Topological Polar Surface Area52.5 Ų
Heavy Atom Count9
Formal Charge0
Complexity60.1
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 Absorption, Distribution and Excretion

19.5 mg/kg (14)C-DIPA in acetone /was applied dermally/ to an area of skin on the shoulder of four female Fisher 344 rats. After evaporation of the solvent /site of application remained covered for 48 hr/. At 48 hr 25% of the substance had penetrated the skin (12% excreted in the urine, 1% excreted in the feces and expired air, 12.5% remaining in the tissue and 73% was recovered from the application site and surroundings.

European Chemicals Bureau; IUCLID Dataset, diisopropanolamine (110-97-4) (2000 CD-ROM edition). Available from, as of September 19, 2005: https://esis.jrc.ec.europa.eu/


When 4 female Fischer-344 rats were injected iv with 19 mg (14)C-labelled diisopropanolamine in aqueous solution, more than 70% of the radioactivity was eliminated from the blood during the first 6 hr. About 90% of the dose was recovered from the urine within 12 hours.

Institution for Statutory Accident Insurance and Prevention in the Chemical Industry (Berufsgenossenschaft der chemischen industrie); Toxicological Evalution No. 178 Diisopropanolamine p.175 (1991)