loader
Please Wait
Applying Filters...

Renejix CDMO Partner for Small Molecule Oral Dosage Forms Renejix CDMO Partner for Small Molecule Oral Dosage Forms

X
menu

    Market Place

    Market Place

    Post Enquiry

    Post Enquiry
    menu

    Technical details about DNL343, learn more about the structure, uses, toxicity, action, side effects and more

    Client Email Product
    Menu

    DNL343

    DEVELOPMENTS

    PRICE INFORMATION

    PharmaCompass

    Biophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

    Athena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

    2D Structure
    1. Also known as: Dnl343, Dnl-343, 2278265-85-1, Fyl3y9d7sk, Schembl20734077, Schembl23358949
    Molecular Formula
    C20H19ClF3N3O4
    Molecular Weight
    457.8  g/mol
    InChI Key
    IKPNRMYDOSNVAU-UHFFFAOYSA-N
    FDA UNII
    FYL3Y9D7SK
    DNL343 is under investigation in clinical trial NCT05842941 (HEALEY ALS Platform Trial - Regimen G DNL343).
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-(4-chlorophenoxy)-N-[3-[5-[3-(trifluoromethoxy)cyclobutyl]-1,3,4-oxadiazol-2-yl]-1-bicyclo[1.1.1]pentanyl]acetamide
    2.1.2 InChI
    InChI=1S/C20H19ClF3N3O4/c21-12-1-3-13(4-2-12)29-7-15(28)25-19-8-18(9-19,10-19)17-27-26-16(30-17)11-5-14(6-11)31-20(22,23)24/h1-4,11,14H,5-10H2,(H,25,28)
    2.1.3 InChI Key
    IKPNRMYDOSNVAU-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1C(CC1OC(F)(F)F)C2=NN=C(O2)C34CC(C3)(C4)NC(=O)COC5=CC=C(C=C5)Cl
    2.2 Other Identifiers
    2.2.1 UNII
    FYL3Y9D7SK
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. Dnl343

    2. Dnl-343

    3. 2278265-85-1

    4. Fyl3y9d7sk

    5. Schembl20734077

    6. Schembl23358949

    7. Schembl24226229

    8. Gtpl12940

    9. Ikpnrmydosnvau-uhfffaoysa-n

    10. Ex-a8745

    11. Hy-149555

    12. Cs-0895874

    13. Acetamide, 2-(4-chlorophenoxy)-n-(3-(5-(cis-3-(trifluoromethoxy)cyclobutyl)-1,3,4-oxadiazol-2-yl)bicyclo(1.1.1)pent-1-yl)-

    2.4 Create Date
    2019-03-16
    3 Chemical and Physical Properties
    Molecular Weight 457.8 g/mol
    Molecular Formula C20H19ClF3N3O4
    XLogP33.7
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count9
    Rotatable Bond Count7
    Exact Mass g/mol
    Monoisotopic Mass g/mol
    Topological Polar Surface Area86.5
    Heavy Atom Count31
    Formal Charge0
    Complexity678
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    Post Enquiry
    POST ENQUIRY