Please Wait
Applying Filters...
menu
    • menu
    Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

    Virtual Booth

    Contact Supplier

    Jai Radhe Sales is your partner for all your sourcing needs.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    Egis is a Hungarian generic pharma company with 110 years history. Our activities incorporate all areas of the pharma value chain.

    Virtual Booth

    Contact Supplier

    Biophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    Menu

    Dobutamine Hydrochloride

    ACTIVE PHARMA INGREDIENTS

    DEVELOPMENTS

    INTERMEDIATES

    FINISHED DOSAGE FORMULATIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    DIGITAL CONTENT

    GLOBAL SALES INFORMATION

    MARKET PLACE

    REF. STANDARDS & IMPURITIES

    PharmaCompass
    $ API Ref.Price (USD/KG) : 563Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: 49745-95-1, Dobutamine hcl, Dobutrex, Inotrex, Dobutamine (hydrochloride), Dl-dobutamine hydrochloride
    Molecular Formula
    C18H24ClNO3
    Molecular Weight
    337.8  g/mol
    InChI Key
    BQKADKWNRWCIJL-UHFFFAOYSA-N
    FDA UNII
    0WR771DJXV
    A catecholamine derivative with specificity for BETA-1 ADRENERGIC RECEPTORS. It is commonly used as a cardiotonic agent after CARDIAC SURGERY and during DOBUTAMINE STRESS ECHOCARDIOGRAPHY.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol;hydrochloride
    2.1.2 InChI
    InChI=1S/C18H23NO3.ClH/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15;/h4-9,12-13,19-22H,2-3,10-11H2,1H3;1H
    2.1.3 InChI Key
    BQKADKWNRWCIJL-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(CCC1=CC=C(C=C1)O)NCCC2=CC(=C(C=C2)O)O.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    0WR771DJXV
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Dobucor

    2. Dobuject

    3. Dobutamin Fresenius

    4. Dobutamin Hexal

    5. Dobutamin Ratiopharm

    6. Dobutamin Solvay

    7. Dobutamin-ratiopharm

    8. Dobutamina Inibsa

    9. Dobutamina Rovi

    10. Dobutamine

    11. Dobutamine (+)-isomer

    12. Dobutamine Hydrobromide

    13. Dobutamine Lactobionate

    14. Dobutamine Phosphate (1:1) Salt, (-)-isomer

    15. Dobutamine Tartrate

    16. Dobutamine Tartrate (1:1), (r-(r*,r*))-isomer

    17. Dobutamine Tartrate (1:1), (s-(r*,r*))-isomer

    18. Dobutamine, (-)-isomer

    19. Dobutamine, Phosphate (1:1) Salt (+)-isomer

    20. Dobutrex

    21. Hydrobromide, Dobutamine

    22. Hydrochloride, Dobutamine

    23. Lactobionate, Dobutamine

    24. Lilly 81929

    25. Oxiken

    26. Posiject

    27. Tartrate, Dobutamine

    2.3.2 Depositor-Supplied Synonyms

    1. 49745-95-1

    2. Dobutamine Hcl

    3. Dobutrex

    4. Inotrex

    5. Dobutamine (hydrochloride)

    6. Dl-dobutamine Hydrochloride

    7. 52663-81-7

    8. Nsc-299583

    9. Rac Dobutamine Hydrochloride

    10. 0wr771djxv

    11. 1,2-benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, Hydrochloride (1:1)

    12. 49745-95-1 (hcl)

    13. 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol Hydrochloride

    14. 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol;hydrochloride

    15. (+-)-4-(2-((3-(p-hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol Hydrochloride

    16. Chebi:4671

    17. 4-(2-((4-(4-hydroxyphenyl)butan-2-yl)amino)ethyl)benzene-1,2-diol Hydrochloride

    18. Smr000058435

    19. Dobutamina Clorhidrato [spanish]

    20. Sr-01000075265

    21. Ly 81929

    22. Einecs 256-464-1

    23. Unii-0wr771djxv

    24. Nsc 299583

    25. Ly 46236

    26. Posiject

    27. 1,2-benzenediol, 4-(2-((3-(4-hydroxyphenyl)-1-methylpropyl)amino)ethyl)-, Hydrochloride

    28. 1,2-benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, Hydrochloride

    29. 4-(2-(4-(4-hydroxyphenyl)butan-2-ylamino)ethyl)benzene-1,2-diol Hydrochloride

    30. 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol Hydrochloride

    31. S-1000

    32. Dobutrex (tn)

    33. 1,2-benzenediol, 4-(2-((3-(4-hydroxyphenyl)-1-methylpropyl)amino)ethyl)-, Hydrochloride (1:1)

    34. Prestwick_741

    35. Mfcd00153795

    36. 1,2-benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-

    37. Dobutamine Hydrochloride In Dextrose 5%

    38. Dobutamine Hydrochloride [usan:usp:ban:jan]

    39. Schembl41609

    40. 1,2-benzenediol, 4-(2-((3-(4-hydroxyphenyl)-1-methylpropyl)amino)ethyl)-, Hydrochloride, (+-)-

    41. Mls000860012

    42. Mls001332503

    43. Mls001332504

    44. Mls002222253

    45. Regid_for_cid_65324

    46. Chembl1200418

    47. Dtxsid30964383

    48. Dobutamine Hydrochloride, >=98%

    49. Dobutamine Hydrochloride In Dextrose 5% In Plastic Container

    50. Hms1569g05

    51. Bcp13026

    52. Tox21_500365

    53. Dobutamine Hydrochloride [mi]

    54. Nsc299583

    55. Dobutamine Hydrochloride (jp17/usp)

    56. Dobutamine Hydrochloride [jan]

    57. Akos015907731

    58. Ccg-220352

    59. Ccg-221669

    60. Dobutamine Hydrochloride [usan]

    61. Ks-1050

    62. Lp00365

    63. (.+-.)-4-[2-[[3-(p-hydroxyphenyl)-1-methylpropyl]amino]ethyl]pyrocatechol Hydrochloride

    64. 4-(2-((3-(p-hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatecholhydrochloride

    65. Dobutamine Hydrochloride [mart.]

    66. Dobutamine Hydrochloride [who-dd]

    67. Ncgc00093799-01

    68. Ncgc00093799-02

    69. Ncgc00261050-01

    70. Ac-11653

    71. Hy-15746

    72. Ly-46236

    73. Db-051684

    74. D4335

    75. Eu-0100365

    76. Ft-0625557

    77. Ft-0681170

    78. Dobutamine Hydrochloride [ep Impurity]

    79. Dobutamine Hydrochloride [orange Book]

    80. D 0676

    81. D00632

    82. Dobutamine Hydrochloride [ep Monograph]

    83. Dobutamine Hydrochloride [usp Impurity]

    84. Dobutamine Hydrochloride [usp Monograph]

    85. 368d042

    86. A827836

    87. Sr-01000075265-1

    88. Sr-01000075265-3

    89. Sr-01000075265-6

    90. W-106009

    91. Q27106435

    92. Dobutamine Hydrochloride, British Pharmacopoeia (bp) Reference Standard

    93. Dobutamine Hydrochloride, European Pharmacopoeia (ep) Reference Standard

    94. 1, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, Hydrochloride, (.+-.)-

    95. 3,4-dihydroxy-n-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenethylamine Hydrochloride

    96. 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]aminoethyl-1,2-benzenediol Hydrochloride

    97. Dobutamine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    98. ( Inverted Question Mark)-4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-1,2-benzenediol Hydrochloride

    99. (+/-)-4-(2-((3-(p-hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol Hydrochloride

    100. 1,2-benzenediol, 4-(2-((3-(4-hydroxyphenyl)-1-methylpropyl)amino)ethyl)-, Hydrochloride, (+/-)-

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 337.8 g/mol
    Molecular Formula C18H24ClNO3
    Hydrogen Bond Donor Count5
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count7
    Exact Mass337.1444713 g/mol
    Monoisotopic Mass337.1444713 g/mol
    Topological Polar Surface Area72.7 Ų
    Heavy Atom Count23
    Formal Charge0
    Complexity305
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameDobutamine hydrochloride
    Drug LabelDobutamine Hydrochloride in 5% Dextrose Injection is a sterile, nonpyrogenic solution of Dobutamine Hydrochloride, USP and Dextrose, USP in Water for Injection, USP. Dobutamine hydrochloride is chemically designated as ()-4-[2-[[3-(p-hydroxyphenyl)...
    Active IngredientDobutamine hydrochloride
    Dosage FormInjectable
    RouteInjection
    Strengtheq 12.5mg base/ml
    Market StatusPrescription
    CompanyHospira; Eurohlth Intl

    2 of 2  
    Drug NameDobutamine hydrochloride
    Drug LabelDobutamine Hydrochloride in 5% Dextrose Injection is a sterile, nonpyrogenic solution of Dobutamine Hydrochloride, USP and Dextrose, USP in Water for Injection, USP. Dobutamine hydrochloride is chemically designated as ()-4-[2-[[3-(p-hydroxyphenyl)...
    Active IngredientDobutamine hydrochloride
    Dosage FormInjectable
    RouteInjection
    Strengtheq 12.5mg base/ml
    Market StatusPrescription
    CompanyHospira; Eurohlth Intl

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Sympathomimetics

    Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)

    Adrenergic beta-1 Receptor Agonists

    Compounds that bind to and activate ADRENERGIC BETA-1 RECEPTORS. (See all compounds classified as Adrenergic beta-1 Receptor Agonists.)

    Cardiotonic Agents

    Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    beta-Adrenergic Agonist [EPC]; Adrenergic beta-Agonists [MoA]