loader
Please Wait
Applying Filters...
menu
    • menu

    Technical details about Encainide, learn more about the structure, uses, toxicity, action, side effects and more

    Client Email Product
    EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

    Virtual Booth

    Contact Supplier

    Bora Pharmaceuticals- Making success more certain.

    Virtual Booth

    Contact Supplier

    Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

    Virtual Booth

    Contact Supplier

    Minakem offers CDMO services for API & HPAPI, generics, regulatory expertise, track record performance & FDA & GMP certifications.

    Virtual Booth

    Contact Supplier

    Axplora- The partner of choice for complex APIs.

    Virtual Booth

    Contact Supplier

    Fareva is a one-stop-shop for API/HPAPI, OSD & Sterile products, is USFDA, EMA and PMDA-inspected and has multiple NDA & ANDA filings.

    Virtual Booth

    Contact Supplier

    Menu

    Encainide

    ACTIVE PHARMA INGREDIENTS

    PharmaCompass
    Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: 66794-74-9, Encainide hcl, Enkaid, Encainide (hydrochloride), Encainide hydrochloride [usan], Mj 9067-1
    Molecular Formula
    C22H29ClN2O2
    Molecular Weight
    388.9  g/mol
    InChI Key
    OJIIZIWOLTYOBS-UHFFFAOYSA-N
    FDA UNII
    4CH7J36N9S
    One of the ANTI-ARRHYTHMIA AGENTS, it blocks VOLTAGE-GATED SODIUM CHANNELS and slows conduction within the His-Purkinje system and MYOCARDIUM.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-methoxy-N-[2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl]benzamide;hydrochloride
    2.1.2 InChI
    InChI=1S/C22H28N2O2.ClH/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18;/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25);1H
    2.1.3 InChI Key
    OJIIZIWOLTYOBS-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CN1CCCCC1CCC2=CC=CC=C2NC(=O)C3=CC=C(C=C3)OC.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    4CH7J36N9S
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Encainide

    2. Encainide Hydrochloride, (+-)-isomer

    3. Encainide, (+)-isomer

    4. Encainide, (-)-isomer

    5. Enkaid

    6. Mj 9067

    7. Mj-9067

    8. Mj9067

    2.3.2 Depositor-Supplied Synonyms

    1. 66794-74-9

    2. Encainide Hcl

    3. Enkaid

    4. Encainide (hydrochloride)

    5. Encainide Hydrochloride [usan]

    6. Mj 9067-1

    7. Mj-9067

    8. Encainidehydrochloride

    9. 4-methoxy-2'-(2-(1-methyl-2-piperidyl)ethyl)benzanilide Hydrochloride

    10. (+-)-2'-(2-(1-methyl-2-piperidyl)ethyl)-p-anisanilide Monohydrochloride

    11. 4ch7j36n9s

    12. Chebi:59880

    13. 4-methoxy-n-[2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl]benzamide;hydrochloride

    14. (+/-)-4-methoxy-n-[2-[2-(1-methyl-2-piperidinyl)ethyl]phenyl]benzamide Hydrochloride

    15. Mj-9067-1

    16. Encainide Hydrochloride (usan)

    17. 2-(2-{2-[(4-methoxybenzoyl)amino]phenyl}ethyl)-1-methylpiperidinium Chloride

    18. 4-methoxy-n-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide Hydrochloride

    19. Enkade; Enkaid;benzamide, 4-methoxy-n-[2-[2-(1-methyl-2-piperidinyl)ethyl]phenyl]-, Monohydrochloride (9ci); Benzamide, 4-methoxy-n-[2-[2-(1-methyl-2-piperidinyl)ethyl]phenyl]-, Monohydrochloride, (+/-)-

    20. Ncgc00185765-01

    21. Unii-4ch7j36n9s

    22. Mfcd01667688

    23. Dsstox_cid_28930

    24. Dsstox_rid_83196

    25. Dsstox_gsid_49004

    26. Mls004712064

    27. Schembl121261

    28. Chembl2106155

    29. Dtxsid2049004

    30. Encainide Hydrochloride [mi]

    31. Tox21_113498

    32. Nsc299238

    33. Akos025311581

    34. Encainide Hydrochloride [mart.]

    35. Encainide Hydrochloride [vandf]

    36. Nsc-299238

    37. Encainide Hydrochloride [who-dd]

    38. Benzamide, 4-methoxy-n-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)-, Monohydrochloride, (+-)-

    39. Hy-12531

    40. Smr002529683

    41. Cas-66794-74-9

    42. Cs-0011988

    43. D03991

    44. H11012

    45. Encainide Hydrochloride, >=98% (hplc), Powder

    46. Q27126935

    47. 4-methoxy-2' -[2-(1-methyl- 2-piperidyl)athyl]benzanilid-hydrochlorid

    48. (+/-)-2'-(2-(1-methyl-2-piperidyl)ethyl)-p-anisanilide Monohydrochloride

    49. Benzamide, 4-methoxy-n-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)-, Monohydrochloride, (+/-)-

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 388.9 g/mol
    Molecular Formula C22H29ClN2O2
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count6
    Exact Mass388.1917559 g/mol
    Monoisotopic Mass388.1917559 g/mol
    Topological Polar Surface Area41.6 Ų
    Heavy Atom Count27
    Formal Charge0
    Complexity434
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Arrhythmia Agents

    Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)

    Voltage-Gated Sodium Channel Blockers

    A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS. (See all compounds classified as Voltage-Gated Sodium Channel Blockers.)